azilma 40 tablet - Azilsartan medoxomil (40mg) medicine

Azilma 40 Tablet - Uses, Price, Side Effects

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๐Ÿญ Rapross Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is azilma 40 tablet used for?

Azilma 40 Tablet contains Azilsartan medoxomil 40mg, an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension). It works by relaxing blood vessels, allowing blood to flow more smoothly and lowering blood pressure. It is typically taken once daily, with or without food.

  • Generic Name: Azilsartan medoxomil
  • Manufacturer: Rapross Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š azilma 40 tablet Uses & Benefits

Hypertension (alone or in combination with other antihypertensives).

Off-label uses: Diabetic nephropathy, heart failure (limited data).

๐Ÿ“‹ Drug Information

Generic Name(s)Azilsartan medoxomil
Brand NameAbel 40 Tablet
ManufacturerRapross Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin receptor blockers(ARB)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached in 1.5-3 hours.
DistributionExtensively distributed; volume of distribution approximately 16 L.
Protein Binding>99% bound to plasma proteins, primarily albumin.
MetabolismMetabolized primarily via CYP2C9 to inactive metabolites; also undergoes glucuronidation.
Half-LifeApproximately 11 hours.
Excretion55% via feces, 42% via urine.
BioavailabilityApproximately 60%.
Onset of ActionWithin 2 weeks of therapy.
Peak Plasma Time1.5-3 hours.
Duration of Action24 hours.

How It Works

Selective angiotensin II receptor blocker (ARB) that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II.

Mechanism Steps

1Azilsartan medoxomil is a prodrug that is hydrolyzed to azilsartan during absorption.
2Azilsartan selectively binds to the angiotensin II type 1 (AT1) receptor.
3Blockade of AT1 receptor prevents angiotensin II-mediated vasoconstriction.

๐Ÿ’ก How to Take azilma 40 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of azilma 40 tablet

โœ… Common Side Effects

  • Dizziness
  • Diarrhea
  • Fatigue
  • Upper respiratory tract infection

๐Ÿšจ Serious Side Effects

  • Hypotension
  • Hyperkalemia
  • Renal impairment
  • Angioedema

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Neutropenia
  • Anaphylactic reaction

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Lithium Moderate Increased lithium levels and toxicity risk
NSAIDs Moderate Reduced antihypertensive effect; increased renal risk
Potassium-sparing diuretics Major Increased risk of hyperkalemia

๐Ÿšจ Major Interactions

  • NSAIDs
  • Lithium
  • Potassium-sparing diuretics
  • ACE inhibitors

โšก Moderate Interactions

  • Antidiabetic agents
  • Digoxin
  • Warfarin

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

May potentiate hypotensive effects; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to azilsartan; concomitant use with aliskiren in patients with diabetes; severe hepatic impairment; pregnancy.

๐Ÿ“Š Monitoring Parameters

Blood pressure, renal function, serum potassium, liver enzymes.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in animal milk, unknown in humans.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; hypotension may be managed with IV fluids and vasopressors.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for azilma 40 tablet

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Alternative brands with exact same active ingredient (Azilsartan medoxomil (40mg)):

Medical Note: Always consult your doctor before switching medications.

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