Azcal 1250mg/250IU Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or vomiting
- Blood in urine or painful urination
- Confusion, excessive thirst, or frequent urination
- Irregular heartbeat or palpitations
- Muscle weakness or bone pain that worsens
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is azcal 1250mg/250iu tablet used for?
This medicine is a calcium and vitamin D3 supplement used to support bone health and treat deficiency. It is taken orally, usually once daily with food, and should be used under medical supervision.
- Generic Name: Calcium + Vitamin D3
- Manufacturer: Bioman Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azcal 1250mg/250iu tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैल्शियम और विटामिन डी3 की कमी को पूरा करने के लिए दी जाती है। यह हड्डियों को मजबूत बनाने, ऑस्टियोपोरोसिस और ऑस्टियोमलेशिया के इलाज में सहायक होती है। महिलाओं में रजोनिवृत्ति के बाद हड्डियों की कमजोरी रोकने के लिए भी इसका इस्तेमाल किया जाता है। यह दवा भोजन के साथ लेनी चाहिए ताकि कैल्शियम और विटामिन डी3 का अवशोषण बेहतर हो।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कब्ज, पेट में गैस, जी मिचलाना और मुँह में चॉकलेट जैसा स्वाद शामिल हैं। कुछ लोगों को पेट में जलन या अपच हो सकती है। दुर्लभ मामलों में बहुत अधिक कैल्शियम के कारण किडनी में पथरी या रक्त में कैल्शियम बढ़ सकता है। अगर आपको लगातार उल्टी, पेट दर्द, कमजोरी या पेशाब में कमी महसूस हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के अनुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं नहीं। भोजन के साथ लेने से पेट की परेशानी कम होती है और अवशोषण बेहतर होता है। अगर आपको किडनी की बीमारी, पथरी, या हाई कैल्शियम की समस्या है तो डॉक्टर को बताएं। आयरन, थायरॉइड की दवा या कुछ एंटीबायोटिक्स के साथ इस दवा को लेने से पहले कम से कम दो घंटे का अंतर रखें। पर्याप्त पानी पिएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 azcal 1250mg/250iu tablet Uses & Benefits
[{"condition":"Calcium and vitamin D deficiency","description":"Used to correct or prevent low calcium levels when diet alone is not enough, especially in people with limited sun exposure or poor dietary intake.","evidence":"Well-established"},{"condition":"Osteoporosis adjunct therapy","description":"Supports bone mineral density when combined with other osteoporosis treatments and adequate dietary calcium.","evidence":"Well-established"},{"condition":"Osteomalacia and rickets prevention","description":"Helps prevent softening of bones caused by vitamin D deficiency, particularly in at-risk populations.","evidence":"Well-established"},{"condition":"Postmenopausal bone health","description":"Provides supplemental calcium and vitamin D to reduce bone loss after menopause.","evidence":"Well-established"},{"condition":"Chronic corticosteroid therapy support","description":"Helps offset steroid-induced bone loss by supplying bone-building minerals.","evidence":"Moderate"},{"condition":"Malabsorption-related deficiency","description":"Used in conditions such as celiac disease or post-bariatric surgery where nutrient absorption is reduced.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Premenstrual syndrome support","description":"Calcium supplementation has been studied for reducing PMS symptoms, but this specific combination is not formally approved for that purpose.","evidence":"Limited"},{"condition":"Colorectal cancer risk reduction","description":"Some observational studies suggest calcium may lower colorectal cancer risk, but evidence is not strong enough for routine recommendation.","evidence":"Limited"},{"condition":"Hypertension adjunct","description":"Adequate calcium intake may have a small effect on blood pressure, but this medicine is not a treatment for high blood pressure.","evidence":"Limited"}]
Primary treatment for: Calcium and vitamin D deficiency
Also treats: Osteoporosis, Osteomalacia, Rickets, Postmenopausal bone loss, Malabsorption syndromes
📋 Drug Information
| Generic Name(s) | Calcium + Vitamin D3 |
| Brand Name | Argical HD Tablet |
| Manufacturer | Bioman Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamin and Mineral Supplement |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container with the lid tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | The World Health Organization recommends adequate calcium and vitamin D intake for bone health, but does not specifically endorse this product. Guidelines emphasize dietary sources and supplementation in at-risk groups. |
| ICMR Guideline | The Indian Council of Medical Research recommends daily calcium and vitamin D intake for bone health. Supplementation is advised for individuals with deficiency or at risk of deficiency, as determined by a clinician. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary nutrients. Calcium is a divalent mineral that is absorbed in the small intestine and becomes the principal structural component of hydroxyapatite crystals in bone and teeth. It also participates in muscle contraction, nerve conduction, blood clotting, and hormone secretion. Vitamin D3, or cholecalciferol, is converted in the liver to 25-hydroxyvitamin D and then in the kidney to its active form, calcitriol. Calcitriol binds to vitamin D receptors in the intestine and increases the production of calcium-binding proteins, which enhances calcium absorption. It also works with parathyroid hormone to regulate calcium release from bone and reabsorption in the kidney. Together, these actions help maintain normal blood calcium levels and support bone mineralization.
Mechanism Steps
💡 How to Take azcal 1250mg/250iu tablet
Strength: Each immediate-release tablet contains calcium 1250 mg and vitamin D3 250 IU.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably with a meal, or as directed by your doctor. The dose may be adjusted based on your calcium and vitamin D levels, dietary intake, and medical condition. Do not exceed the dose prescribed by your clinician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults often require calcium and vitamin D supplementation, but the dose should be individualized based on kidney function, dietary intake, and other medicines. Elderly patients may be more prone to constipation and hypercalcaemia, so regular monitoring is advised. |
| Renal Impairment | Patients with mild to moderate kidney impairment may need dose adjustment and monitoring of calcium and vitamin D levels. This medicine is contraindicated in severe renal impairment or kidney failure unless specifically directed by a nephrologist. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Vitamin D is metabolized in the liver, so patients with severe liver disease should use this medicine under medical supervision. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescriber's recommendation. In general, total elemental calcium intake from all sources should not exceed 2000 mg per day for adults, and vitamin D intake should not exceed the safe upper limit for your age unless medically supervised. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azcal 1250mg/250iu tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Thiazide diuretics | Major | |
| Digoxin | Major | |
| Tetracycline antibiotics | Major | |
| Fluoroquinolone antibiotics | Major | |
| Levothyroxine | Major | |
| Iron supplements | Moderate | |
| Bisphosphonates | Moderate | |
| Corticosteroids | Moderate | |
| Orlistat | Moderate | |
| Bile acid sequestrants | Moderate |
🚨 Major Interactions
- Thiazide diuretics
- Digoxin and other cardiac glycosides
- Tetracycline and doxycycline antibiotics
- Fluoroquinolone antibiotics
- Levothyroxine
⚡ Moderate Interactions
- Iron supplements
- Bisphosphonates
- Corticosteroids
- Orlistat
- Bile acid sequestrants
🍷 Alcohol Interaction
Moderate alcohol consumption is unlikely to cause a direct interaction with this medicine, but heavy or chronic alcohol use can impair calcium absorption, reduce bone density, and increase the risk of falls and fractures. It is best to limit alcohol intake while taking this medicine and to discuss your alcohol use with your doctor if you have bone health concerns.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypercalcaemia (high blood calcium levels)","Hypercalciuria (high calcium in urine)","Severe renal impairment or kidney failure","History of calcium-containing kidney stones","Vitamin D toxicity","Sarcoidosis","Hyperparathyroidism","Known allergy to any ingredient in this medicine"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose without medical advice.","Use with caution in patients with kidney disease or a history of kidney stones.","Monitor calcium levels if you are taking thiazide diuretics or digoxin.","Separate this medicine from iron, thyroid medicines, and certain antibiotics by at least two hours.","Avoid taking additional calcium or vitamin D supplements without consulting your doctor.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Keep out of reach of children.","Do not use after the expiry date printed on the pack."]
🤱 Lactation Safety
Calcium and vitamin D3 are excreted in breast milk and are considered compatible with breastfeeding when taken at recommended doses. Breastfeeding women often need higher calcium and vitamin D intake. Consult your doctor to determine the right dose for you and your baby.
💊 Overdose Management
Overdose of this medicine can cause hypercalcaemia, nausea, vomiting, confusion, excessive thirst, frequent urination, and irregular heartbeat. If you suspect an overdose, stop the medicine and seek immediate medical attention. Treatment may include stopping calcium and vitamin D intake, intravenous fluids, and medications to lower calcium levels. Do not try to treat yourself at home.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided it is not almost time for your next dose. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as directed by your doctor or pharmacist. Swallow the tablet whole with a full glass of water, preferably with food, to help absorption and reduce the chance of stomach upset. Do not crush, chew, or split the tablet unless your clinician has told you it is acceptable. Keep your intake of other calcium-containing products, such as antacids and multivitamins, in mind because total daily calcium from all sources should not exceed the safe upper limit for your age. Drink plenty of water throughout the day to help prevent constipation and kidney stone formation. Tell your doctor if you have a history of kidney stones, kidney disease, sarcoidosis, or high blood calcium. Avoid taking this medicine within two hours of iron supplements, thyroid medicines, or certain antibiotics because calcium can reduce their absorption. Do not start or stop this medicine without medical advice, especially if you are pregnant, breastfeeding, or planning a pregnancy. Store the tablets in their original container, away from moisture and direct sunlight, and keep them out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to need calcium and vitamin D supplementation, but they are also at higher risk of constipation and hypercalcaemia. Kidney function declines with age, so dose adjustment and monitoring may be necessary. Ensure adequate hydration and fall prevention measures.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss your calcium and vitamin D needs with your doctor. Adequate intake is important for both maternal and fetal bone health. Do not exceed the recommended dose unless prescribed.
🏥 Post-Surgery Considerations
After surgery, especially orthopedic surgery, your doctor may recommend calcium and vitamin D supplementation to support bone healing. Follow your surgeon's instructions and do not self-medicate. Inform your surgical team about all supplements you are taking.
🦷 Dental Procedures
This medicine does not typically interfere with dental procedures. However, inform your dentist about all medicines and supplements you take. Adequate calcium and vitamin D are important for jawbone health and dental implant healing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular weight-bearing and muscle-strengthening exercises are beneficial for bone health while taking this medicine. However, if you have osteoporosis or are at risk of fractures, avoid high-impact activities and sudden twisting movements. Consult your doctor or physiotherapist before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or muscle weakness from low calcium or other causes, avoid driving until you feel well. Take it with food to minimize stomach upset that could affect your workday.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience side effects such as severe constipation, nausea, or signs of hypercalcaemia, contact your doctor. Your doctor may adjust the dose or recommend stopping based on your calcium and vitamin D levels and overall health.
📅 Long-Term Use Effects
Long-term use of this medicine at recommended doses is generally safe and helps maintain bone health. However, excessive intake over long periods can lead to hypercalcaemia, kidney stones, and soft tissue calcification. Regular monitoring of calcium and vitamin D levels, kidney function, and bone density is advised for people on long-term therapy. Your doctor may adjust the dose based on your test results and clinical condition.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing intake of dairy, leafy greens, fortified foods, and safe sun exposure can help maintain levels.
Evidence: Well-establishedRegular exercise helps maintain bone density and complements supplementation.
Evidence: Well-establishedCalcium citrate may be better absorbed in people with low stomach acid.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive routine vaccinations while taking this supplement. If you have any concerns, discuss them with your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking your dose at the same time relative to your meals. Check customs regulations for nutritional supplements before you travel. Keep enough supply for your entire trip and carry it in your hand luggage if possible.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine works gradually. It may take several weeks to months to correct calcium and vitamin D levels and see improvements in bone health. Follow your doctor's advice for monitoring.
A: It is best taken with food to improve absorption and reduce stomach upset. Taking it on an empty stomach may increase the risk of nausea and constipation.
A: If you remember within a few hours, take the missed dose. If it is almost time for your next dose, skip it and continue with your regular schedule. Do not double dose.
A: Do not take additional calcium or vitamin D supplements without consulting your doctor, as excessive intake can be harmful.
A: People with kidney disease should use this medicine only under medical supervision because calcium and vitamin D can affect kidney function and calcium levels.
🤔 Common Patient Concerns
🔄 Substitutes for azcal 1250mg/250iu tablet
View AllAlternative brands with exact same active ingredient:
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cypacal forte tabletCyper Drugs & Pharmaceuticals Pvt Ltd ₹18.00 21.7% CHEAPER
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knob d 1250mg/250iu tabletCambist Biotech Pvt Ltd ₹27.00 17.4% COSTLIER
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kandy tabletBiosans Lifecare ₹35.00 52.2% COSTLIER
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Refocal D 1250mg/250IU TabletPlenus Pharmaceuticals Pvt Ltd ₹39.75 72.8% COSTLIER
-
calport 1250mg/250iu tabletAlports Healthcare Pvt Ltd ₹61.50 167.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Calcium supplements can be taken at any time without food.
Fact: Calcium is better absorbed when taken with food, and vitamin D3 needs dietary fat for optimal absorption. - Myth: More calcium always means stronger bones.
Fact: Excessive calcium can cause side effects and does not provide extra benefit beyond the recommended intake. - Myth: This medicine can replace a healthy diet.
Fact: Supplements are meant to complement, not replace, a balanced diet rich in calcium and vitamin D. - Myth: Calcium supplements cause kidney stones in everyone.
Fact: Kidney stones are a rare risk mainly in people with a history of stones or excessive intake.
🔄 Alternative Options
Generic Alternatives
- Calcium carbonate + Vitamin D3 tablets
- Calcium citrate + Vitamin D3 tablets
Brand Alternatives
- Shelcal 500
- Calcirol
- Uprise D3
- Gemcal
- Ostocalcium