avosun tablet - Promethazine (25mg) medicine

Avosun Tablet - Uses, Price, Side Effects

4.5 (19 reviews)
๐Ÿญ Sun Life Sciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is avosun tablet used for?

Avosun Tablet contains Promethazine 25mg, an antihistamine used to prevent and treat nausea, vomiting, and motion sickness. It works by blocking histamine and acting on the brain's vomiting center. It is also used for allergic reactions and as a sedative.

  • Generic Name: Promethazine
  • Manufacturer: Sun Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š avosun tablet Uses & Benefits

Nausea and vomiting, Motion sickness, Allergic conditions, Sedation

Off-label uses: Insomnia, Anxiety

๐Ÿ“‹ Drug Information

Generic Name(s)Promethazine
Brand NameAvomine
ManufacturerSun Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassH1 Antihistaminics (First Generation)
Route of AdministrationOral, intramuscular, intravenous, rectal
StorageStore at room temperature (20-25ยฐC); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration achieved in 2-3 hours.
DistributionWidely distributed; crosses blood-brain barrier and placenta.
Protein BindingApproximately 93% bound to plasma proteins.
MetabolismHepatic metabolism via CYP2D6; major metabolite is promethazine sulfoxide.
Half-Life10-14 hours
ExcretionPrimarily renal as metabolites; small amount unchanged.
BioavailabilityApproximately 25% due to first-pass metabolism.
Onset of Action20-30 minutes
Peak Plasma Time2-3 hours
Duration of Action4-6 hours

How It Works

Antagonizes histamine H1 receptors; also has anticholinergic, antiemetic, and sedative effects.

Mechanism Steps

1Binds to histamine H1 receptors
2Blocks histamine-mediated effects
3Inhibits vestibular stimulation in the inner ear

๐Ÿ’ก How to Take avosun tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of avosun tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Blurred vision

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Seizures
  • Extrapyramidal symptoms
  • Neuroleptic malignant syndrome

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Leukopenia
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CNS Depressants Major Increased sedation and respiratory depression
MAO Inhibitors Major Risk of severe hypotension and extrapyramidal symptoms
Anticholinergics Moderate Additive anticholinergic effects

๐Ÿšจ Major Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines)
  • MAO inhibitors

โšก Moderate Interactions

  • Anticholinergic drugs
  • Other antihistamines

โ„น๏ธ Minor Interactions

  • CYP2D6 substrates

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

Enhanced CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to promethazine, Comatose states, CNS depression, Children <2 years (risk of respiratory depression)

๐Ÿ“Š Monitoring Parameters

CNS depression, Respiratory rate, Blood pressure

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; treat hypotension and respiratory depression.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for avosun tablet

View All

Alternative brands with exact same active ingredient (Promethazine (25mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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