avnac oral drops - Uses, Price, Side Effects & Substitutes
What is avnac oral drops used for?
Ascoril Flu Syrup (Chlorpheniramine Maleate + Phenylephrine) is used to treat RESPIRATORY. It contains Chlorpheniramine Maleate (2mg/ml) + Phenylephrine (2.5mg/ml), which Chlorpheniramine blocks histamine H1 receptors; Phenylephrine stimulates alpha-1. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlorpheniramine Maleate + Phenylephrine
- Manufacturer: Afive Pharma
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ avnac oral drops Uses & Benefits
Symptomatic relief of common cold, allergic rhinitis, sinusitis
Off-label uses: Not commonly used off-label
๐ Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Phenylephrine |
| Brand Name | Ascoril Flu Syrup |
| Manufacturer | Afive Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlorpheniramine blocks histamine H1 receptors; Phenylephrine stimulates alpha-1 adrenergic receptors causing vasoconstriction
Mechanism Steps
๐ก How to Take avnac oral drops
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of avnac oral drops
โ Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Nausea
- Headache
- Insomnia
๐จ Serious Side Effects
- Hypertension
- Arrhythmias
- Seizures
- Urinary retention
- Hallucinations
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis |
| Beta-blockers | Major | Reduced efficacy of both drugs |
| Tricyclic antidepressants | Major | Increased risk of hypertension and arrhythmias |
| Antihypertensives | Moderate | Reduced antihypertensive effect |
| CNS depressants | Moderate | Increased sedation |
| Sympathomimetics | Moderate | Additive pressor effects |
| Anticholinergics | Minor | Additive anticholinergic effects |
| Digoxin | Minor | Possible increased digoxin toxicity |
๐จ Major Interactions
- MAOIs
- Beta-blockers
- Tricyclic antidepressants
โก Moderate Interactions
- Antihypertensives
- CNS depressants
- Sympathomimetics
โน๏ธ Minor Interactions
- Anticholinergics
- Digoxin
๐ฝ๏ธ Food Interactions
Avoid alcohol; may increase CNS depression
๐ท Alcohol Interaction
Increased sedation and CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hypertension, coronary artery disease, MAOI use within 14 days, narrow-angle glaucoma, urinary retention
๐ Monitoring Parameters
Blood pressure, heart rate, CNS effects, urinary output
๐คฑ Lactation Safety
Use with caution; may be excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; consider activated charcoal, monitor vitals, treat arrhythmias if needed
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.