anticold oral drops - Chlorpheniramine Maleate (2mg/ml) + Phenylephrine (5mg/ml) medicine

Anticold Oral Drops: Complete Medicine Guide

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🏭 Surya Pharmaceutical Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe headache or blurred vision
  • Chest pain or irregular heartbeat
  • Difficulty breathing or swelling of face, lips, or throat
  • Inability to urinate
  • Seizures or severe drowsiness
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is anticold oral drops used for?

This medicine is a combination of chlorpheniramine maleate (an antihistamine) and phenylephrine (a decongestant) used to relieve symptoms of the common cold and allergic rhinitis, such as runny nose, sneezing, and nasal congestion. It works by blocking histamine and constricting nasal blood vessels. It is for short-term use and may cause drowsiness.

  • Generic Name: Chlorpheniramine Maleate + Phenylephrine
  • Manufacturer: Surya Pharmaceutical Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anticold oral drops के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी-जुकाम और एलर्जी से होने वाले लक्षणों जैसे नाक बहना, छींक आना, नाक बंद होना और खुजली को कम करने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और फेनिलएफ्रिन दो सक्रिय तत्व हैं। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए और लंबे समय तक नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना और जी मिचलाना शामिल हैं। कभी-कभी दिल की धड़कन तेज होना, रक्तचाप बढ़ना और पेशाब करने में कठिनाई जैसे गंभीर दुष्प्रभाव भी हो सकते हैं। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के अनुसार ही लें। इसकी मात्रा से अधिक न लें। दवा लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। अगर आपको उच्च रक्तचाप, हृदय रोग, मधुमेह या थायरॉइड की समस्या है तो डॉक्टर को बताएं। 7 दिनों से अधिक इसका उपयोग न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 anticold oral drops Uses & Benefits

[{"condition":"Common cold","description":"Relieves nasal congestion, runny nose, sneezing, and itching associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, rhinorrhea, and nasal itching caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps relieve nasal congestion and pressure in sinusitis, though it does not treat the infection itself.","evidence":"Supportive"}]

Off-label uses: [{"condition":"Eustachian tube dysfunction","description":"Sometimes used to reduce congestion and improve ear pressure equalization.","evidence":"Limited"}]

Primary treatment for: Common cold and allergic rhinitis

Also treats: Sinusitis, Eustachian tube dysfunction

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate + Phenylephrine
Brand NameAscoril Flu Syrup
ManufacturerSurya Pharmaceutical Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use the dropper provided to measure the exact dose; household spoons are not accurate.
2
Take this medicine with food or milk if it upsets your stomach.
3
Avoid driving or operating machinery until you know how this medicine affects you.
4
Do not use this medicine for more than 7 days without consulting a doctor.
5
Check with your doctor before combining with other cold or allergy medicines to avoid duplicate ingredients.
6
Keep a record of your symptoms to help your doctor assess the effectiveness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine helps relieve sneezing due to allergies or cold.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Body ache
This medicine does not relieve body aches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally, but its bioavailability is limited due to first-pass metabolism in the gut and liver.
DistributionChlorpheniramine maleate is widely distributed throughout body tissues and crosses the blood-brain barrier, which contributes to its sedative effects. Phenylephrine distribution is not well characterized but is expected to distribute to vascular tissues.
Protein BindingChlorpheniramine maleate is approximately 70% bound to plasma proteins. Protein binding of phenylephrine is not established from the available information.
MetabolismChlorpheniramine maleate is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6. Phenylephrine undergoes extensive first-pass metabolism in the gut and liver, mainly by monoamine oxidase and sulfation.
Half-LifeThe elimination half-life of chlorpheniramine maleate is approximately 12 to 43 hours in adults. The elimination half-life of phenylephrine is not established from the available information.
ExcretionChlorpheniramine maleate and its metabolites are excreted primarily in the urine. Phenylephrine is excreted in the urine as metabolites and unchanged drug.
BioavailabilityThe oral bioavailability of chlorpheniramine maleate is approximately 25% to 50%. The oral bioavailability of phenylephrine is low, estimated at less than 10% due to first-pass metabolism.
Onset of ActionThe onset of action for chlorpheniramine maleate is typically within 30 to 60 minutes after oral administration. The onset of action for phenylephrine is also within 30 to 60 minutes.
Peak Plasma TimePeak plasma concentrations of chlorpheniramine maleate are reached approximately 2 to 6 hours after oral administration. Peak plasma concentrations of phenylephrine are reached within 1 to 2 hours.
Duration of ActionThe duration of action for chlorpheniramine maleate is approximately 4 to 6 hours. The duration of action for phenylephrine is approximately 4 to 6 hours.

How It Works

This medicine combines two active ingredients. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, and runny nose. Phenylephrine is an alpha-1 adrenergic receptor agonist that causes vasoconstriction in the nasal mucosa, leading to decreased swelling and congestion. The combination provides symptomatic relief of cold and allergy symptoms.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine maleate binds to H1 receptors on blood vessels and nerve endings, preventing histamine from causing vasodilation, increased permeability, and itching.
2
Alpha-1 adrenergic receptor activation: Phenylephrine stimulates alpha-1 receptors on nasal blood vessels, causing them to constrict and reduce blood flow, which decreases swelling and congestion.
3
Symptom relief: The combined actions reduce sneezing, runny nose, and nasal stuffiness, providing relief from cold and allergy symptoms.

💡 How to Take anticold oral drops

Strength: Each mL contains chlorpheniramine maleate 2 mg and phenylephrine 5 mg.

1Shake the bottle well before use.
2Use the dropper provided to measure the exact dose.
3Take orally, with or without food.
4Follow the prescribed dose and duration.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1 to 2 mL (2 to 4 mg chlorpheniramine and 5 to 10 mg phenylephrine) orally every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose for adults is 12 mL (24 mg chlorpheniramine and 60 mg phenylephrine) in divided doses. Do not exceed this limit.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals if stomach upset occurs
Reduces gastrointestinal discomfort.
Alcohol
Avoid
Increases drowsiness and cardiovascular effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anticold oral drops

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If drowsiness persists or interferes with daily activities, consult your doctor.
Dry mouth (Common (5-15%))
Sip water frequently or chew sugarless gum. If severe, consult your doctor.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid sudden movements.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Hypertensive crisis (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you develop rash, itching, swelling of face or throat, or difficulty breathing.
Urinary retention (Rare (<0.1%))
Consult a doctor if you are unable to urinate or have difficulty passing urine.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising, bleeding, or signs of infection to your doctor.
Seizures
Seek immediate medical attention if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Moderate
CNS depressants Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Beta-blockers
  • Central nervous system depressants

🍷 Alcohol Interaction

Alcohol increases the sedative effects of chlorpheniramine and may enhance the cardiovascular effects of phenylephrine. Avoid alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine maleate or phenylephrine","Severe hypertension","Coronary artery disease","Use with MAOIs","Narrow-angle glaucoma","Urinary retention"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Do not use for more than 7 days without medical advice.","Use with caution in patients with hypertension, heart disease, diabetes, or thyroid disorders.","Avoid alcohol and other CNS depressants.","Not recommended for children under 2 years of age.","Consult a doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

Chlorpheniramine maleate and phenylephrine may pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, rapid heartbeat, high blood pressure, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine, as it can increase drowsiness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, or difficulty urinating. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as drowsiness, confusion, and urinary retention. Use with caution and consider lower doses under medical supervision.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect blood pressure.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with anesthetics or other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Use a humidifier to ease nasal congestion.
💧
Avoid exposure to allergens and irritants.
🧘
Wash your hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine, especially if you experience drowsiness or dizziness. Light activity is generally safe, but listen to your body and rest if needed.

🥗 Diet Recommendations

Include warm soups and broths to soothe your throat.
Avoid cold beverages and ice cream if they worsen your symptoms.
Eat a balanced diet rich in vitamins and minerals to support immunity.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid tasks requiring alertness until you know how it affects you. It is advisable to take it at bedtime if it makes you sleepy.

🛑 When to Stop This Medicine

Stop taking this medicine if your symptoms do not improve within 7 days or if they worsen. Consult your doctor before stopping if you have been using it regularly for a longer period.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of phenylephrine can lead to rebound nasal congestion. Chlorpheniramine may cause persistent drowsiness and anticholinergic effects. Regular monitoring of blood pressure and symptoms is advised if used for more than a few days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Steam inhalation

May temporarily ease nasal stuffiness.

Evidence: Supportive

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature and avoid exposure to extreme heat or cold. If traveling across time zones, continue your regular dosing schedule as advised by your doctor. Do not pack it in checked luggage; keep it in your carry-on bag.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She started taking this medicine as prescribed for her runny nose and sneezing. Within 30 minutes, her symptoms improved significantly. She experienced mild drowsiness, so she took it at bedtime. She was advised not to drive after taking it.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while providing relief from allergy symptoms.
👤 A 50-year-old man with common cold and hypertension
He used this medicine for nasal congestion but experienced an increase in blood pressure. He consulted his doctor, who advised him to stop it and prescribed an alternative decongestant safe for hypertensive patients.
💡 Lesson: Patients with high blood pressure should use this medicine with caution and under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after oral administration.

Q: Can I take it with other cold medicines?

A: Consult your doctor before combining with other cold medicines to avoid overlapping ingredients and potential side effects.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anticold oral drops

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Anticold oral drops can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take anticold oral drops for extended periods.
    Fact: Prolonged use can lead to rebound congestion and other side effects. It should be used short-term.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine maleate + phenylephrine oral drops

📊 Comparison with Similar Medicines

[{"medicine":"Chlorpheniramine + phenylephrine","sedation":"High","blood_pressure_effect":"Moderate","onset":"30-60 min"},{"medicine":"Cetirizine + phenylephrine","sedation":"Low","blood_pressure_effect":"Moderate","onset":"30-60 min"},{"medicine":"Loratadine + phenylephrine","sedation":"Low","blood_pressure_effect":"Moderate","onset":"1-3 hours"}]

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