avcaine oral gel - Oxetacaine (10mg/5ml) + Aluminium Hydroxide (0.291gm/5ml) medicine

avcaine oral gel - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Avilius Neutracare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is avcaine oral gel used for?

Acicaine Oral Gel (Oxetacaine + Aluminium Hydroxide) is used to treat GASTRO INTESTINAL. It contains Oxetacaine (10mg/5ml) + Aluminium Hydroxide (0.291gm/5ml), which Aluminium hydroxide neutralizes gastric acid; oxetacaine provides local anesthet. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Oxetacaine + Aluminium Hydroxide
  • Manufacturer: Avilius Neutracare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š avcaine oral gel Uses & Benefits

Symptomatic relief of hyperacidity, heartburn, gastroesophageal reflux disease, peptic ulcer

Off-label uses: Stress ulcer prophylaxis, Prevention of aspiration pneumonitis

๐Ÿ“‹ Drug Information

Generic Name(s)Oxetacaine + Aluminium Hydroxide
Brand NameAcicaine Oral Gel
ManufacturerAvilius Neutracare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntacid + Local Anesthetic
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from freezing
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionPoorly absorbed from gastrointestinal tract
DistributionMinimal systemic distribution; acts locally in GI tract
Protein BindingNot applicable (minimal systemic absorption)
MetabolismNot metabolized significantly
Half-LifeNot applicable
ExcretionPrimarily fecal
BioavailabilityNegligible systemic bioavailability
Onset of ActionRapid (within minutes)
Peak Plasma TimeNot applicable
Duration of Action1-2 hours

How It Works

Aluminium hydroxide neutralizes gastric acid; oxetacaine provides local anesthetic effect on gastric mucosa

Mechanism Steps

1Aluminium hydroxide reacts with gastric acid to form aluminium chloride and water, raising pH
2Oxetacaine stabilizes neuronal membranes by blocking sodium channels, reducing pain sensation
3Combined effect reduces acidity and provides local analgesia

๐Ÿ’ก How to Take avcaine oral gel

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of avcaine oral gel

โœ… Common Side Effects

  • Constipation
  • Nausea
  • Vomiting
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Hypophosphatemia
  • Osteomalacia (long-term high doses)
  • Aluminium toxicity (renal impairment)

โš ๏ธ Rare Side Effects

  • Metabolic alkalosis
  • Hypomagnesemia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tetracyclines Major Reduced absorption of tetracycline
Iron supplements Major Reduced iron absorption
Fluoroquinolones Major Reduced absorption of quinolones
Digoxin Major Reduced digoxin absorption

๐Ÿšจ Major Interactions

  • Tetracyclines
  • Iron supplements
  • Fluoroquinolones
  • Digoxin

โšก Moderate Interactions

  • Sodium polystyrene sulfonate
  • Mycophenolate mofetil

โ„น๏ธ Minor Interactions

  • Vitamin D analogues
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

Dairy products may reduce efficacy

๐Ÿท Alcohol Interaction

May increase gastric irritation

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe renal impairment (aluminium accumulation)

๐Ÿ“Š Monitoring Parameters

Serum phosphate, aluminium levels (long-term use), renal function

๐Ÿคฑ Lactation Safety

Generally considered safe; minimal systemic absorption

๐Ÿ’Š Overdose Management

Gastric lavage, supportive measures; monitor electrolytes

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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