avacan 80mg tablet - Uses, Price, Side Effects & Substitutes
What is avacan 80mg tablet used for?
Antispasmin DS 80mg Tablet (Drotaverine) is used to treat GASTRO INTESTINAL. It contains Drotaverine (80mg), which Inhibits phosphodiesterase-4 (PDE4), increasing cAMP, leading to smooth muscle r. Always consult your doctor before use. Take as prescribed.
- Generic Name: Drotaverine
- Manufacturer: Khandelwal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ avacan 80mg tablet Uses & Benefits
Smooth muscle spasms in GI disorders, biliary colic, renal colic, dysmenorrhea.
Off-label uses: Premature labor (not FDA approved).
๐ Drug Information
| Generic Name(s) | Drotaverine |
| Brand Name | Antispasmin DS 80mg Tablet |
| Manufacturer | Khandelwal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Phosphodiesterase-IV inhibitors (Smooth Muscle Relaxant) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits phosphodiesterase-4 (PDE4), increasing cAMP, leading to smooth muscle relaxation.
Mechanism Steps
๐ก How to Take avacan 80mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of avacan 80mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dizziness
- Headache
- Dry mouth
๐จ Serious Side Effects
- Hypotension
- Arrhythmias
- Allergic reactions
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Leukopenia
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Levodopa | Major | Reduced efficacy of levodopa |
| Tricyclic antidepressants | Major | Increased anticholinergic effects |
| Antihypertensives | Moderate | Additive hypotensive effect |
| Other anticholinergics | Moderate | Increased anticholinergic side effects |
| Cimetidine | Minor | Possible increased drotaverine levels |
| Ranitidine | Minor | Possible increased drotaverine levels |
๐จ Major Interactions
- Levodopa
- Tricyclic antidepressants
โก Moderate Interactions
- Antihypertensives
- Other anticholinergics
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase risk of hypotension and dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to drotaverine, severe hepatic or renal impairment, porphyria.
๐ Monitoring Parameters
Blood pressure, liver function tests in long-term use.
๐คฑ Lactation Safety
Caution advised; excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive treatment; no specific antidote.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for avacan 80mg tablet
View AllAlternative brands with exact same active ingredient (Drotaverine (80mg)):
-
dropain 80mg tabletEthix Healthcare โน3.75 91.3% CHEAPER
-
drozen 80mg injectionVentus Pharmaceuticals Pvt Ltd โน13.13 69.5% CHEAPER
-
dguta 80mg injectionPharmacon Healthcare โน13.13 69.5% CHEAPER
-
mudot 80mg injectionMepfarma India Pvt Ltd โน14.00 67.4% CHEAPER
-
drovera 80mg injectionManeesh Pharmaceuticals Ltd โน17.25 59.9% CHEAPER
-
stayhappi drotaverine 80mg tabletSarvagunaushdhi Pvt Ltd โน20.00 53.5% CHEAPER
-
dotamin 80mg injectionProtech Telelinks โน26.25 39% CHEAPER
-
drotaspa 80mg tabletShreya Life Sciences Pvt Ltd โน28.43 33.9% CHEAPER
-
dito 80mg tabletLifecom Pharmaceuticals Pvt Ltd โน29.90 30.5% CHEAPER
-
inorine 80mg tabletInd Swift Laboratories Ltd โน29.90 30.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.