atrest 25mg tablet - Hydroxyzine (25mg) medicine

atrest 25mg tablet

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Hydroxyzine (25mg)
🏭 Windlas Biotech Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is atrest 25mg tablet used for?

This medicine contains Hydroxyzine (25mg) and is used to treat RESPIRATORY. Antagonizes histamine H1 receptors; suppresses activity in subcortical brain regions. Always consult your doctor before use.

  • Generic Name: Hydroxyzine
  • Manufacturer: Windlas Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 atrest 25mg tablet Uses & Benefits

Pruritus, Urticaria, Anxiety, Preoperative sedation, Nausea/vomiting

Off-label uses: Insomnia, Chemotherapy-induced nausea

📋 Drug Information

Generic Name(s)Hydroxyzine
Brand NameAtarax
ManufacturerWindlas Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassH1 Antihistaminics (First Generation)
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration within 2 hours
DistributionWidely distributed; crosses blood-brain barrier
Protein Binding93%
MetabolismHepatic via CYP3A4 and CYP2D6; major metabolite cetirizine
Half-Life20 hours (range 14-25 hours)
ExcretionPrimarily renal (as metabolites)
Bioavailability80% (oral)
Onset of Action15-30 minutes
Peak Plasma Time2 hours
Duration of Action4-6 hours (antihistamine); up to 24 hours (anxiolytic)

How It Works

Antagonizes histamine H1 receptors; suppresses activity in subcortical brain regions

Mechanism Steps

1Binds to histamine H1 receptors on target cells
2Blocks histamine-mediated effects (vasodilation, bronchoconstriction, pruritus)
3Suppresses activity in subcortical brain regions (sedation, anxiolysis)
4Exhibits anticholinergic effects at higher doses

💡 How to Take atrest 25mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of atrest 25mg tablet

✅ Common Side Effects

Drowsiness
Dry mouth
Headache
Fatigue

🚨 Serious Side Effects

QT prolongation
Seizures
Urinary retention
Hypotension

⚠️ Rare Side Effects

Agranulocytosis
Hepatitis
Allergic reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

🚨 Major Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines)
  • MAOIs
  • Anticholinergics

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP2D6 inhibitors (e.g., fluoxetine)

🍷 Alcohol Interaction

Increased CNS depression; avoid concurrent use

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to hydroxyzine or cetirizine, Porphyria, Prolonged QT interval

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

🔄 Substitutes for atrest 25mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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