anti spas 10mg/250mg tablet - Dicyclomine (10mg) + Mefenamic Acid (250mg) medicine

Anti Spas 10mg/250mg Tablet - Uses, Price, Side Effects

4.7 (16 reviews)
๐Ÿญ Windlas Biotech Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is anti spas 10mg/250mg tablet used for?

Anti Spas 10mg/250mg Tablet is a combination medicine used to treat abdominal pain and cramps due to conditions like irritable bowel syndrome. Dicyclomine relaxes intestinal muscles, while Mefenamic Acid reduces pain and inflammation. It works by blocking muscle contractions and inhibiting prostaglandin synthesis.

  • Generic Name: Dicyclomine + Mefenamic Acid
  • Manufacturer: Windlas Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š anti spas 10mg/250mg tablet Uses & Benefits

Treatment of abdominal cramps, dysmenorrhea, and other smooth muscle spasms associated with pain

Off-label uses: Renal colic, biliary colic, migraine (limited evidence)

๐Ÿ“‹ Drug Information

Generic Name(s)Dicyclomine + Mefenamic Acid
Brand NameAlmefkem Spas 10mg/250mg Tablet
ManufacturerWindlas Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAntispasmodic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses placenta and enters breast milk
Protein BindingDicyclomine: ~90%; Mefenamic Acid: >90%
MetabolismDicyclomine: Hepatic; Mefenamic Acid: Hepatic via CYP2C9
Half-LifeDicyclomine: 1.8-2.5 hours; Mefenamic Acid: 2-4 hours
ExcretionDicyclomine: Urine and feces; Mefenamic Acid: Urine (primarily as metabolites) and feces
BioavailabilityDicyclomine: ~67%; Mefenamic Acid: ~90%
Onset of ActionDicyclomine: 1-2 hours; Mefenamic Acid: 1-2 hours
Peak Plasma TimeDicyclomine: 1-1.5 hours; Mefenamic Acid: 2-4 hours
Duration of ActionDicyclomine: 4-6 hours; Mefenamic Acid: 6-8 hours

How It Works

Dicyclomine: Antimuscarinic, relaxes smooth muscle; Mefenamic Acid: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis

Mechanism Steps

1Dicyclomine blocks muscarinic acetylcholine receptors on smooth muscle cells, reducing parasympathetic tone and causing relaxation.
2Mefenamic acid inhibits cyclooxygenase (COX-1 and COX-2) enzymes, decreasing conversion of arachidonic acid to prostaglandins.
3Reduced prostaglandins lead to decreased pain, inflammation, and fever.

๐Ÿ’ก How to Take anti spas 10mg/250mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of anti spas 10mg/250mg tablet

โœ… Common Side Effects

  • Dizziness
  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Drowsiness
  • Blurred vision

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Pancreatitis
  • Interstitial nephritis
  • Aseptic meningitis
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels and toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โšก Moderate Interactions

  • Antihypertensives
  • SSRIs
  • Antidiabetic agents
  • Digoxin
  • Phenytoin
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; avoid alcohol

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, active GI bleeding, peptic ulcer disease, severe renal/hepatic impairment, history of asthma, third trimester pregnancy, children <6 months

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of GI bleeding, blood pressure

๐Ÿคฑ Lactation Safety

Use with caution; may pass into breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; induce emesis or gastric lavage; monitor for CNS depression, seizures, arrhythmias

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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