Acemol MF Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit, or black tarry stools
- Severe or worsening abdominal pain
- Yellowing of the eyes or skin
- Very little or no urine output
- Swelling of the face, lips, or throat
- Difficulty breathing or wheezing
- Severe skin rash with blisters or peeling
- Unusual bruising or bleeding
- Extreme sleepiness or difficulty waking the child
- Fever that does not come down after 3 days of treatment
If experiencing severe symptoms, call emergency services immediately.
What is anti spas oral suspension used for?
This medicine is a pediatric oral syrup that combines mefenamic acid 50 mg and paracetamol 125 mg in each 5 mL. It is used for short-term relief of mild to moderate pain and fever in children. It should be given only as prescribed by a doctor, with food, and for a short time. Do not combine it with other paracetamol-containing medicines.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: Windlas Biotech Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anti spas oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा बच्चों में हल्के से मध्यम दर्द और बुखार के लिए इस्तेमाल की जाने वाली ओरल सिरप है। इसमें मेफेनैमिक एसिड 50 मिलीग्राम और पैरासिटामोल 125 मिलीग्राम प्रति 5 मिलीलीटर होता है। यह दांत निकलने का दर्द, कान का दर्द, गले में खराश, सिरदर्द, शरीर दर्द, टीकाकरण के बाद होने वाला बुखार और चोट के बाद के दर्द में राहत देने के लिए दी जाती है। यह दवा सूजन और बुखार को भी कम करती है। इसे डॉक्टर की सलाह के अनुसार ही देना चाहिए और खाने के साथ या खाने के तुरंत बाद देना चाहिए। इसे लंबे समय तक नहीं देना चाहिए।
साइड इफेक्ट्स: इस दवा से आमतौर पर पेट दर्द, जी मिचलाना, उल्टी, दस्त, भूख कम लगना, नींद आना, चक्कर आना और सिरदर्द हो सकता है। कभी-कभी त्वचा पर दाने या खुजली हो सकती है। बहुत कम मामलों में पेट या आंत में खून आना, गुर्दे या लिवर की समस्या, गंभीर एलर्जी या सांस लेने में तकलीफ हो सकती है। अगर बच्चे की नजर में पीलापन, काला मल, खून की उल्टी, बहुत कम पेशाब, चेहरे या गले में सूजन या सांस लेने में दिक्कत हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही दें और बोतल के साथ मिली मापने वाली चम्मच या सिरिंज का ही इस्तेमाल करें। हर बार देने से पहले बोतल को अच्छी तरह हिलाएं। इसे खाने के साथ या खाने के तुरंत बाद दें ताकि पेट में जलन न हो। बच्चे को पानी या ओआरएस देकर हाइड्रेटेड रखें। इस दवा के साथ कोई और पैरासिटामोल वाली दवा न दें। बुखार के लिए 3 दिन से ज्यादा और दर्द के लिए 5 दिन से ज्यादा बिना डॉक्टर की सलाह के इस्तेमाल न करें। 6 महीने से छोटे बच्चों को डॉक्टर की सलाह के बिना यह दवा न दें।
💊 anti spas oral suspension Uses & Benefits
[{"condition":"Mild to moderate pain with fever in children","description":"Used for short-term relief of pain and fever associated with common childhood illnesses such as viral fever, sore throat, ear pain, and body ache.","evidence":"Well-established for short-term symptomatic use"},{"condition":"Teething pain","description":"Helps reduce gum discomfort and irritability in infants and young children during teething, when prescribed by a pediatrician.","evidence":"Commonly used, short-term relief"},{"condition":"Post-immunization fever and pain","description":"May be used to ease fever and local pain after routine vaccinations, as advised by the doctor.","evidence":"Commonly used, short-term relief"},{"condition":"Post-operative or post-traumatic pain","description":"Sometimes prescribed for short-term relief of mild to moderate pain after minor procedures or injuries in children.","evidence":"Limited to short-term use under medical supervision"}]
Off-label uses: [{"condition":"Juvenile idiopathic arthritis pain flare","description":"May be used short-term for pain relief during flares, but it is not a disease-modifying treatment and must be supervised by a specialist.","evidence":"Limited; specialist supervision required"},{"condition":"Primary dysmenorrhea in adolescents","description":"Mefenamic acid is sometimes used for menstrual pain in adolescent girls, but this syrup formulation is not typically chosen for that purpose.","evidence":"Limited for this formulation"}]
Primary treatment for: Mild to moderate pain with fever in children
Also treats: Teething pain, Post-immunization fever, Sore throat with fever, Ear pain with fever, Body ache with viral fever, Post-traumatic pain
📋 Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | Windlas Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed. Do not freeze. Keep out of reach of children. |
| Shelf Life | Not established from the available information. Check the expiry date printed on the bottle and do not use after that date. |
| WHO Guideline | Not established from the available information for this specific fixed-dose combination syrup. The World Health Organization does not recommend fixed-dose combination NSAID and paracetamol syrups for routine pediatric use. Always follow the prescribing doctor's advice. |
| ICMR Guideline | Not established from the available information for this specific fixed-dose combination syrup. Indian guidelines generally advise cautious, short-term use of NSAIDs in children and avoidance of unnecessary fixed-dose combinations. Follow the treating doctor's advice. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary pathways. Mefenamic acid is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes, mainly COX-1 and COX-2, which are needed to convert arachidonic acid into prostaglandins and thromboxanes. Lower prostaglandin levels reduce pain, swelling, and fever at the site of injury or infection. Paracetamol acts mainly in the central nervous system, where it reduces prostaglandin synthesis and may also affect pain and temperature regulation pathways in the brain and spinal cord. The combination gives both anti-inflammatory and central analgesic and antipyretic effects, which is why it is used for short-term relief of pain with fever in children.
Mechanism Steps
💡 How to Take anti spas oral suspension
Strength: Oral syrup containing mefenamic acid 50 mg and paracetamol 125 mg in each 5 mL.
Dosage Information
| Adult Dosage | This syrup formulation is mainly intended for children. Adults should not use this pediatric syrup unless a doctor specifically prescribes it, because the strength per 5 mL is low for adult needs. If an adult is prescribed this medicine, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Adults should not exceed the prescribed dose and should not use it for more than a few days without medical review. |
| Pediatric Dosage | Pediatric dosing must be determined by a qualified pediatrician based on the child's age, weight, and clinical condition. This syrup contains mefenamic acid 50 mg and paracetamol 125 mg in each 5 mL. Do not calculate the dose yourself. Use the measuring cup or oral syringe supplied with the bottle. Do not give this medicine to children under 6 months of age unless a pediatrician specifically prescribes it. Do not exceed the prescribed frequency or duration. |
| Elderly Dosage | This pediatric syrup is not intended for elderly patients. If an elderly person is prescribed this medicine, the dose must be individualized by a qualified clinician because older adults have a higher risk of stomach bleeding, kidney problems, and liver injury. Elderly patients should use the lowest effective dose for the shortest possible time. |
| Renal Impairment | Use with caution in children with kidney disease. The dose must be individualized by a qualified clinician based on kidney function. Avoid use in severe kidney disease. Keep the child well hydrated and monitor urine output. |
| Hepatic Impairment | Use with caution in children with liver disease. The dose must be individualized by a qualified clinician based on liver function. Avoid use in severe liver disease. Do not combine with other paracetamol-containing medicines. |
| Maximum Daily Dose | The maximum daily dose must be determined by the prescribing doctor based on the child's age, weight, and clinical condition. Do not exceed the prescribed dose. For paracetamol, the total daily dose from all sources should not exceed the doctor's recommended limit. For mefenamic acid, the total daily dose should not exceed the doctor's recommended limit. Never give more than the prescribed number of doses in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anti spas oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other paracetamol products | Major | |
| Warfarin | Major | |
| Ibuprofen or other NSAIDs | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Carbamazepine | Moderate |
🚨 Major Interactions
- Other paracetamol-containing products
- Warfarin and other anticoagulants
- Other NSAIDs such as ibuprofen, naproxen, or aspirin
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and angiotensin receptor blockers
- Diuretics such as furosemide
- Corticosteroids
- Selective serotonin reuptake inhibitors
- Carbamazepine and phenytoin
🍷 Alcohol Interaction
Alcohol should not be given to children, and it should be avoided by adolescents or adults taking this medicine. Alcohol increases the risk of stomach bleeding from mefenamic acid and raises the risk of liver injury from paracetamol. If a teenager or adult is taking this medicine, they should not drink alcohol until the course is finished and the doctor says it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to mefenamic acid, paracetamol, or any other ingredient in this medicine","Active stomach or intestinal ulcer or history of NSAID-related bleeding","Severe kidney disease","Severe liver disease","Asthma, urticaria, or allergic reaction triggered by aspirin or other NSAIDs","Children under 6 months of age unless specifically prescribed by a pediatrician","Dehydration or shock","Bleeding disorders or active bleeding","Use before or after heart bypass surgery"]
⚠️ Warnings & Precautions
["Do not give this medicine for more than 3 days for fever or more than 5 days for pain without medical advice.","Do not combine with any other paracetamol-containing medicine.","Give with food or milk to reduce stomach upset.","Keep the child well hydrated.","Avoid in children with kidney or liver disease unless a doctor approves.","Stop and seek medical help if the child has signs of stomach bleeding, allergic reaction, or liver problems.","Do not use in children who have asthma triggered by NSAIDs.","Use the measuring device supplied with the bottle, not a household spoon.","Store out of reach of children."]
🤱 Lactation Safety
Mefenamic acid passes into breast milk in small amounts, and paracetamol also passes into breast milk in small amounts. Short-term use may be considered by a doctor if clearly needed, but breastfeeding mothers should not use this medicine without medical advice. Watch the baby for drowsiness, poor feeding, or rash if the doctor approves its use.
💊 Overdose Management
Overdose of this medicine can cause serious liver injury from paracetamol and stomach or kidney problems from mefenamic acid. If you think a child has taken too much, do not wait for symptoms. Contact a poison control center or take the child to the nearest emergency department immediately. Bring the bottle or packaging with you. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not try to make the child vomit unless a doctor tells you to.
⏰ Missed Dose
If you miss a dose, give it as soon as you remember, unless it is almost time for the next dose. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give a double dose to make up for a missed one. If you are unsure, contact the child's doctor or pharmacist.
Additional Safety Advice
Give this medicine exactly as prescribed by the child's doctor, using the measuring cup or oral syringe that comes with the bottle. Shake the bottle well before each dose. Give it with or just after food to reduce stomach upset. Do not give any other medicine that contains paracetamol at the same time, because the total paracetamol dose can become unsafe for the liver. Keep the child well hydrated with water or oral rehydration solution. Do not use this medicine for more than 3 days for fever or more than 5 days for pain unless the doctor advises otherwise. Do not give this medicine to children under 6 months of age unless a pediatrician specifically prescribes it. Store the bottle tightly closed at room temperature, away from direct sunlight and out of reach of children. If the child has kidney disease, liver disease, asthma, stomach ulcers, or a bleeding disorder, tell the doctor before giving this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This pediatric syrup is not intended for elderly patients. If an elderly person is prescribed this medicine, they should use the lowest effective dose for the shortest possible time because older adults have a higher risk of stomach bleeding, kidney problems, and liver injury. They should also be monitored for interactions with blood thinners, blood pressure medicines, and other pain relievers.
🤰 Pregnancy Planning (TTC)
This medicine is not intended for use during pregnancy planning. Women who are trying to conceive should avoid NSAIDs such as mefenamic acid because they may interfere with ovulation and are best avoided around conception. Paracetamol may be used during pregnancy only when clearly needed and advised by a doctor. If you are planning pregnancy and need pain or fever relief, consult your doctor for a safer option.
🏥 Post-Surgery Considerations
This medicine may be prescribed for short-term pain relief after minor surgery in children, but it should only be used under medical supervision. After major surgery, pain management should be directed by the surgical team. Inform the surgeon and anesthesiologist about all medicines the child is taking, including this one, before any procedure. Do not use this medicine to self-treat post-surgical pain without medical advice.
🦷 Dental Procedures
This medicine may be used for short-term pain relief after dental procedures such as tooth extraction or fillings in children, if prescribed by the dentist or doctor. Inform the dentist about all medicines the child is taking. Do not give this medicine before a dental procedure unless the dentist advises it. For dental pain, treating the underlying cause is more important than repeated pain relief.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Children should rest during fever and acute pain. Once the fever settles and the child feels better, gentle play and normal activity can resume. Avoid strenuous sports or heavy physical activity while the child is taking this medicine, especially if they feel dizzy or sleepy. If the child has a muscle or joint injury, follow the doctor's advice about returning to activity.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is mainly used in children, so it does not directly affect adult work life. Parents may need to stay home to care for a sick child. The medicine can cause sleepiness or dizziness in some children, so they should avoid activities that need full alertness, such as cycling, swimming, or playing contact sports, until the effect wears off. Adolescents taking this medicine should avoid driving or operating machinery if they feel sleepy or dizzy.
🛑 When to Stop This Medicine
Stop this medicine when the child's fever and pain have settled, or after the number of days advised by the doctor, whichever is earlier. Do not stop or continue on your own beyond the prescribed duration. If the child develops any red-flag symptoms such as blood in stool, severe stomach pain, yellow eyes, or difficulty breathing, stop the medicine and seek medical help immediately. Always consult the doctor before stopping if the child is on a longer prescribed course.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of mefenamic acid can increase the risk of stomach ulcers, gastrointestinal bleeding, kidney problems, and liver injury. Long-term paracetamol use above the recommended dose can cause liver damage. If a child needs pain or fever relief for more than a few days, the doctor should reassess the underlying cause and consider other treatments. Regular monitoring of kidney and liver function may be needed if long-term use is unavoidable.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A single-ingredient paracetamol syrup may be enough for mild fever and pain, with fewer stomach side effects.
Evidence: Well-establishedAn alternative NSAID syrup that may be used for fever, pain, and inflammation if the child can take it safely.
Evidence: Well-establishedSponging with lukewarm water, light clothing, and good hydration can help comfort a child with fever.
Evidence: Supportive careNon-medicine methods can help soothe teething discomfort and reduce the need for pain medicines.
Evidence: Supportive care💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may be used for short-term relief of fever and pain after routine vaccinations, as advised by the doctor. It does not replace vaccination and does not affect the vaccine's ability to build immunity when used appropriately. Do not give this medicine before vaccination unless the doctor specifically advises it. Follow the national immunization schedule and consult the pediatrician about fever management after each vaccine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless the label says so
✅ DO
Keep the bottle tightly closed in its original carton
❌ DON'T
Do not transfer the syrup to another container
✅ DO
Keep away from direct sunlight and heat
❌ DON'T
Do not store in a hot car or near a stove
✅ DO
Keep out of reach of children
❌ DON'T
Do not leave the bottle open or within a child's reach
✅ DO
Check the expiry date before each use
❌ DON'T
Do not use expired or discolored syrup
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original bottle with the label and the measuring device. Keep a copy of the child's prescription with you, especially for international travel. Store the bottle at room temperature and protect it from direct sunlight and extreme heat. Do not leave it in a hot car or in checked luggage. If you are crossing time zones, continue giving the medicine at the intervals prescribed by the doctor, but do not give extra doses to make up for time changes. Check the expiry date before use, and do not use the medicine if it has changed color or has particles in it.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief and fever reduction usually begin within 30 to 60 minutes after giving the dose. The full effect is usually seen within 1 to 4 hours.
A: Yes. Giving this medicine with food or milk reduces the chance of stomach upset.
A: Do not give any other paracetamol-containing medicine with this syrup, because the total paracetamol dose can become unsafe for the liver. Ask the doctor before adding any other medicine.
A: Use it only for the duration advised by the doctor, usually no more than 3 days for fever and 5 days for pain. If symptoms continue, contact the doctor.
A: If the child vomits within 15 to 30 minutes of a dose, contact the doctor or pharmacist for advice. Do not repeat the dose on your own.
A: It should not be given to children under 6 months of age unless a pediatrician specifically prescribes it.
🤔 Common Patient Concerns
🔄 Substitutes for anti spas oral suspension
View AllAlternative brands with exact same active ingredient:
-
fevel m syrupNovique Life Sciences ₹25.31 61.1% CHEAPER
-
mefpra syrupImmuna Life Sciences ₹25.31 61.1% CHEAPER
-
paragos m oral suspensionSegos Biocare ₹26.25 59.6% CHEAPER
-
ufipar m oral suspensionZeeford Life Sciences ₹26.53 59.2% CHEAPER
-
aike oral suspensionGlacia Life Care ₹26.58 59.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be given for any fever without a doctor's advice.
Fact: This medicine contains an NSAID and paracetamol, so it should only be used when prescribed by a doctor for the right indication and duration. - Myth: More syrup means faster fever relief.
Fact: Giving more than the prescribed dose can cause serious liver, kidney, and stomach problems. Always follow the prescribed dose. - Myth: It is safe to combine this medicine with other paracetamol syrups.
Fact: Combining paracetamol-containing medicines can lead to a dangerous total paracetamol dose and liver injury. - Myth: This medicine can be used for weeks for teething pain.
Fact: It should only be used short-term. Long-term use increases the risk of stomach, kidney, and liver problems. - Myth: This medicine is safe for newborns.
Fact: It should not be given to children under 6 months of age unless a pediatrician specifically prescribes it.
🔄 Alternative Options
Generic Alternatives
- Mefenamic acid and paracetamol oral suspension
Brand Alternatives
- Acemol MF Syrup