Artyfar 150mg Injection (Arteether): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, swelling of the face or throat, or a severe rash
- Fainting, chest discomfort, or a very slow or irregular heartbeat
- Confusion, seizures, or loss of consciousness
- Yellowing of the eyes or skin, dark urine, or severe tiredness
- Increasing pain, redness, or pus at the injection site
- High fever that does not come down after treatment
- Very low urine output or swelling of the body
If experiencing severe symptoms, call emergency services immediately.
What is atmal 150mg injection used for?
This medicine is an intramuscular antimalarial injection containing arteether. It is used to treat severe falciparum malaria when a patient cannot take oral medicines. It is given by a healthcare professional once daily for three days, followed by a full course of oral antimalarial therapy.
- Generic Name: Arteether
- Manufacturer: Biosans Lifecare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 atmal 150mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा आर्टीथर नामक एंटीमलेरियल इंजेक्शन है, जिसका उपयोग गंभीर और जटिल फाल्सीपेरम मलेरिया के इलाज के लिए किया जाता है। जब मरीज मलेरिया की गोलियाँ निगल नहीं पा रहा हो, बार-बार उल्टी हो रही हो, बेहोशी हो या हालत बहुत गंभीर हो, तब यह इंजेक्शन डॉक्टर या नर्स द्वारा मांसपेशी में लगाया जाता है। यह दवा मलेरिया के परजीवी को तेजी से मारती है और बुखार तथा अन्य लक्षणों को कम करने में मदद करती है। यह आमतौर पर तीन दिन तक रोज एक बार लगाई जाती है, और उसके बाद मलेरिया की गोलियों का पूरा कोर्स करना बहुत जरूरी होता है। यह दवा घर पर खुद से नहीं लगाई जाती और इसे सिर्फ अस्पताल या क्लिनिक में ही लगवाना चाहिए।
साइड इफेक्ट्स: इस दवा को सही तरीके से लगाने पर ज्यादातर लोग इसे अच्छी तरह सहन कर लेते हैं। इंजेक्शन लगाने की जगह पर दर्द, सूजन या छोटी गांठ हो सकती है। कुछ लोगों को हल्का बुखार, सिरदर्द, चक्कर, जी मिचलाना, उल्टी या पेट में असहजता हो सकती है। ये आमतौर पर एक-दो दिन में ठीक हो जाते हैं। कभी-कभी गंभीर एलर्जी हो सकती है, जिसमें चकत्ते, खुजली, चेहरे या गले में सूजन या सांस लेने में तकलीफ हो सकती है। बहुत कम मामलों में दिल की धड़कन धीमी या अनियमित हो सकती है, लीवर पर असर पड़ सकता है या खून की जांच में बदलाव दिख सकते हैं। अगर सांस लेने में दिक्कत, बेहोशी, सीने में तकलीफ, आँखों का पीला होना या गहरे रंग का पेशाब हो, तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह इंजेक्शन सिर्फ डॉक्टर या प्रशिक्षित नर्स द्वारा ही लगाया जाना चाहिए, घर पर कभी नहीं। इसे नस में नहीं, बल्कि मांसपेशी में गहरा लगाया जाता है। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दिल की धड़कन या लीवर पर असर डालने वाली दवाएं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं या आपको दिल, लीवर या किडनी की बीमारी है, तो डॉक्टर को जरूर बताएं। इंजेक्शन लगने की जगह को साफ रखें और उसे रगड़ें नहीं। इंजेक्शन के बाद मलेरिया की गोलियों का पूरा कोर्स जरूर करें, भले ही आप बिल्कुल ठीक महसूस करें। इलाज के दौरान शराब न पिएं। अगर दोबारा बुखार, बेहोशी, दौरे, सांस लेने में तकलीफ, सीने में दर्द या दिल की धड़कन बहुत धीमी लगे, तो तुरंत अस्पताल जाएं।
💊 atmal 150mg injection Uses & Benefits
[{"condition":"Severe falciparum malaria","description":"This medicine is used as initial treatment for severe or complicated Plasmodium falciparum malaria, particularly when oral therapy is not possible.","evidence":"Well-established"},{"condition":"Complicated malaria with vomiting or unconsciousness","description":"It is given by intramuscular injection when the patient cannot swallow oral antimalarials because of vomiting, altered consciousness, or severe weakness.","evidence":"Well-established"},{"condition":"Cerebral malaria","description":"Arteether is used as part of the management of cerebral malaria in hospital settings, followed by a full oral antimalarial course.","evidence":"Well-established"},{"condition":"Malaria in patients unable to take oral medicines","description":"It provides a parenteral treatment option for patients who cannot tolerate or absorb oral antimalarial drugs.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Other severe malaria species","description":"It may occasionally be used for severe non-falciparum malaria when standard treatments are unavailable or unsuitable, but this is not a routine use.","evidence":"Limited"}]
Primary treatment for: Severe falciparum malaria
Also treats: Cerebral malaria, Complicated malaria with vomiting or unconsciousness, Severe malaria in patients unable to take oral medicines
📋 Drug Information
| Generic Name(s) | Arteether |
| Brand Name | Artisun 150mg Injection |
| Manufacturer | Biosans Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial- Artemisinin and derivatives |
| Route of Administration | Intramuscular injection. This medicine is given as a deep intramuscular injection, usually into the buttock, by a trained healthcare professional |
| Storage | Store in a cool, dry place, protected from light. Do not freeze. Keep the injection vial or ampoule in its original packaging until use. Follow the storage instructions printed on the pack. |
| Shelf Life | Not established from the available information. Always check the expiry date on the pack before use. |
| WHO Guideline | Not established from the available information. Treatment of severe malaria should follow current national and international guidelines, and the choice of medicine should be made by a qualified clinician. |
| ICMR Guideline | Not established from the available information. In India, severe malaria treatment should follow the latest national guidelines and institutional protocols. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Arteether is an artemisinin derivative that kills malaria parasites rapidly. Inside the parasite, it is activated by iron and heme to form reactive free radicals and reactive oxygen species. These reactive molecules damage parasite proteins, membranes, and essential organelles, including the parasite's digestive vacuole and mitochondria. This leads to rapid destruction of the blood-stage parasites and reduces the parasite burden quickly. Arteether is most active against the asexual blood stages of Plasmodium falciparum, which are responsible for the symptoms and complications of malaria.
Mechanism Steps
💡 How to Take atmal 150mg injection
Strength: Arteether 75 mg/ml intramuscular injection, supplied as a 150 mg dose (2 ml of 75 mg/ml) in the pack described.
Dosage Information
| Adult Dosage | The usual adult dose is 150 mg given as a deep intramuscular injection once daily for three days, but the exact dose and duration must be individualized by a qualified clinician based on the severity of malaria, body weight, kidney and liver function, and response to treatment. This medicine is always followed by a full course of oral antimalarial therapy. Do not self-administer this injection. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine may be used in children with severe malaria only under specialist supervision, with the dose determined by the child's weight and clinical condition. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially effects on the heart and liver. The dose must be individualized by a qualified clinician, and heart rhythm and liver function should be monitored more closely. |
| Renal Impairment | Specific dose adjustments for kidney disease are not established from the available information. Because severe malaria itself can affect the kidneys, kidney function should be checked and the dose decided by a qualified clinician. |
| Hepatic Impairment | This medicine is metabolized in the liver, so patients with liver disease may need closer monitoring. Specific dose adjustments are not established from the available information. The treating doctor will decide the dose based on liver function and clinical condition. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. The dose must be determined by a qualified clinician based on the patient's condition. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of atmal 150mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Mefloquine | Major | |
| Lumefantrine | Major | |
| QT-prolonging drugs | Major | |
| Rifampicin | Moderate | |
| Ketoconazole | Moderate | |
| Paracetamol | Moderate | |
| Warfarin | Moderate | |
| Other liver-affecting medicines | Moderate | |
| Oral antimalarials | Minor | |
| Vitamin supplements | Minor |
🚨 Major Interactions
- Mefloquine
- Lumefantrine
- Drugs that prolong QT interval (for example, certain antiarrhythmics, antipsychotics, and antibiotics)
- Strong inhibitors or inducers of liver enzymes (for example, ketoconazole, rifampicin)
⚡ Moderate Interactions
- Paracetamol
- Other liver-affecting medicines
- Anticoagulants such as warfarin
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine. Alcohol can increase the risk of liver problems, worsen dizziness and nausea, and may interfere with your ability to recover from severe malaria. It can also make it harder to judge your condition if side effects occur.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to arteether or any other artemisinin derivative","Use for mild malaria that can be treated with oral medicines","Self-administration outside a healthcare setting","Use without a follow-up oral antimalarial course","Use in patients with certain severe heart rhythm problems unless the doctor decides it is absolutely necessary"]
⚠️ Warnings & Precautions
["This medicine must be given only by a trained healthcare professional as a deep intramuscular injection.","Do not inject into a vein or into the wrong site, as this can cause serious problems.","Tell your doctor about all other medicines, especially those that affect heart rhythm or the liver.","Use with caution in patients with heart, liver, or kidney disease.","Complete the full oral antimalarial course after the injections to prevent relapse.","Avoid alcohol during treatment.","Report any unusual symptoms such as fainting, chest discomfort, confusion, or yellowing of the eyes immediately."]
🤱 Lactation Safety
It is not known whether arteether passes into breast milk in significant amounts. Because this medicine is given for severe malaria, breastfeeding decisions should be made by the treating doctor. In many cases, breastfeeding may continue while the mother receives treatment under medical supervision.
💊 Overdose Management
Overdose with this medicine is unlikely when it is given by a healthcare professional. If too much is given by mistake, the patient should be monitored in a hospital for heart rhythm changes, low blood pressure, and other symptoms. Treatment is supportive and may include close cardiac monitoring and standard emergency care. There is no specific antidote established from the available information.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or clinic, a missed dose is uncommon. If a scheduled injection is missed, contact the treating doctor or hospital as soon as possible. Do not try to make up for the missed injection at home. The doctor will decide the best way to continue the treatment schedule.
Additional Safety Advice
This medicine must be given only by a qualified doctor or nurse as a deep intramuscular injection, never at home and never into a vein. Tell your doctor about all your other medicines, especially heart rhythm medicines, antimalarials such as mefloquine or lumefantrine, and drugs that affect the liver. Inform the doctor if you are pregnant, breastfeeding, or have heart, liver, or kidney disease. Do not rub or massage the injection site, and keep the area clean and dry. Complete the full course of oral antimalarial medicine prescribed after the injections, even if you feel completely well, because stopping early can allow the malaria to return. Avoid alcohol during treatment. Return to the hospital immediately if you develop fever again, confusion, fits, breathing difficulty, chest pain, or a very slow heartbeat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine on the heart and liver. They should be monitored closely during treatment, and the dose should be decided by a qualified clinician based on their overall health and organ function.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss malaria prevention with your doctor before you conceive. If you develop severe malaria during pregnancy, this medicine may be used only when a doctor decides that the benefit clearly outweighs the risk. Untreated severe malaria is dangerous for both mother and baby, so do not delay treatment.
🏥 Post-Surgery Considerations
If you have recently had surgery and develop severe malaria, this medicine may be used under close medical supervision. Inform the surgeon and the treating doctor about all medicines you are taking, and follow their advice about monitoring and follow-up.
🦷 Dental Procedures
Tell your dentist about your recent malaria treatment and any medicines you are taking. There is no specific interaction between this medicine and common dental procedures, but your overall health should be stable before any planned dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid heavy exercise and strenuous activity during treatment for severe malaria. Rest is important while your body recovers. Once your doctor says you are well enough, you can slowly return to your normal activities. Stop and rest if you feel dizzy, breathless, or very tired.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Severe malaria and its treatment can keep you away from work for one to two weeks. You may feel weak and tired for some days after the injections. Do not drive or operate heavy machines until you feel fully alert and your doctor approves. Ask your employer for sick leave and follow your doctor's advice about when to return to work.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. The injection course is short and is decided by your doctor. After the injections, you must complete the full oral antimalarial course even if you feel completely well. If you develop serious side effects such as breathing difficulty, fainting, or yellowing of the eyes, stop and seek immediate medical help. Always consult your doctor before stopping any medicine.
📅 Long-Term Use Effects
This medicine is usually given for a short course of three days, so long-term effects are uncommon. Rarely, temporary changes in liver enzymes or blood cell counts may occur. Patients who have had severe malaria need follow-up to check for anemia, kidney problems, and other complications of the disease itself. If you notice ongoing tiredness, yellowing of the eyes, or repeated fever, see your doctor for a full check-up.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another artemisinin derivative often preferred for severe malaria in many guidelines.
Evidence: Well-establishedAn intramuscular artemisinin derivative used for severe malaria.
Evidence: Well-establishedAn older treatment used when artemisinins are not available, with careful monitoring.
Evidence: Well-establishedUsing nets, repellents, and eliminating stagnant water helps prevent malaria.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. However, if you are very ill with severe malaria, vaccination may be postponed until you recover. Discuss the timing of any vaccines with your doctor.
📦 Storage Guide
✅ DO
Store in a cool, dry place protected from light
❌ DON'T
Do not freeze the injection
✅ DO
Keep the vial or ampoule in its original packaging
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Check the expiry date before use
❌ DON'T
Do not use if the solution is cloudy or has particles
✅ DO
Keep out of reach of children
❌ DON'T
Do not store in a hot or damp place
✈️ Traveling with This Medicine
If you are travelling after treatment for severe malaria, carry a copy of your prescription and discharge summary. Keep any remaining oral antimalarial medicines in their original packaging with the pharmacy label. Store the medicines in a cool, dry place and protect them from direct sunlight. If you are travelling to another country, check the local rules about carrying prescription medicines and carry a doctor's letter if needed. Do not stop the oral course during travel, and plan follow-up blood tests as advised by your doctor.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The medicine starts working within hours. Fever and other symptoms usually improve within 24 to 48 hours, but the full course must be completed.
A: No. This medicine is an injection that must be given only by a trained healthcare professional in a hospital or clinic.
A: You must complete a full course of oral antimalarial medicine prescribed by your doctor to prevent the malaria from returning.
A: It should be used in pregnancy only when a doctor decides that the benefit clearly outweighs the risk, especially in severe malaria where untreated disease is dangerous.
A: No. This medicine treats severe malaria. It does not prevent malaria. Prevention requires avoiding mosquito bites and taking preventive medicines when advised.
🤔 Common Patient Concerns
🔄 Substitutes for atmal 150mg injection
View AllAlternative brands with exact same active ingredient:
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falcimether injectionIntas Pharmaceuticals Ltd ₹12.60 82.5% CHEAPER
-
mosther 75mg injectionLinnet Life Sciences ₹23.44 67.4% CHEAPER
-
Stanther 150mg InjectionStandard Remedies Pvt Ltd ₹24.68 65.7% CHEAPER
-
laristar 150mg injectionBaltic Pharmaceuticals ₹42.19 41.4% CHEAPER
-
depther 75mg/ml injectionDaksh Pharma Pvt Ltd ₹45.00 37.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home like a tablet.
Fact: This medicine is an injection that must be given only by a trained healthcare professional in a hospital or clinic. - Myth: Once the fever settles, no further treatment is needed.
Fact: A full course of oral antimalarial medicine must be completed after the injections to prevent the malaria from returning. - Myth: This medicine prevents malaria.
Fact: This medicine treats severe malaria. It does not prevent malaria. Prevention requires avoiding mosquito bites and taking preventive medicines when advised. - Myth: More injections mean faster recovery.
Fact: The number of injections is decided by the doctor based on the severity of illness. Extra doses can be harmful.
🔄 Alternative Options
Generic Alternatives
- Arteether injection
- Artesunate injection
- Artemether injection
Brand Alternatives
- Artyfar 150mg injection