Ativak 500mg Injection - Uses, Price, Side Effects
What is ativak 500mg injection used for?
Ativak 500mg Injection contains Amikacin, an aminoglycoside antibiotic used to treat serious bacterial infections such as septicemia, respiratory tract infections, urinary tract infections, and intra-abdominal infections. It works by binding to bacterial ribosomes, inhibiting protein synthesis, and causing bacterial cell death. It is typically administered intravenously or intramuscularly under medical supervision.
- Generic Name: Amikacin
- Manufacturer: H & Care Incorp
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ ativak 500mg injection Uses & Benefits
Serious Gram-negative infections (sepsis, pneumonia, complicated UTI, intra-abdominal infections); adjunct in tuberculosis; neonatal sepsis.
Off-label uses: Brucellosis, Plague, Tularemia
๐ Drug Information
| Generic Name(s) | Amikacin |
| Brand Name | Amikacin Sulphate 500mg Injection |
| Manufacturer | H & Care Incorp |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Aminoglycosides |
| Route of Administration | Intramuscular, Intravenous |
| Storage | Store at 20-25ยฐC; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis.
Mechanism Steps
๐ก How to Take ativak 500mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of ativak 500mg injection
โ Common Side Effects
- Nephrotoxicity
- Ototoxicity (vestibular and cochlear)
- Nausea
- Vomiting
- Rash
๐จ Serious Side Effects
- Acute renal failure
- Irreversible hearing loss
- Neuromuscular blockade
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Superinfection
- Clostridium difficile colitis
- Hypomagnesemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | Increased risk of nephrotoxicity and ototoxicity |
| Furosemide | Major | Increased risk of ototoxicity |
| Cisplatin | Major | Increased risk of nephrotoxicity and ototoxicity |
| Vancomycin | Moderate | Increased risk of nephrotoxicity |
| Neuromuscular blocking agents | Moderate | Enhanced neuromuscular blockade |
๐จ Major Interactions
- Neuromuscular blocking agents
- Other aminoglycosides
- Cisplatin
- Loop diuretics
- Vancomycin
โก Moderate Interactions
- Penicillins (synergy)
- Cephalosporins
- NSAIDs
- Methoxyflurane
โน๏ธ Minor Interactions
- Dimercaprol
- Indomethacin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amikacin or other aminoglycosides; myasthenia gravis; pre-existing severe renal impairment.
๐ Monitoring Parameters
Renal function (serum creatinine, BUN), urine output, audiometry, serum drug levels (peak and trough).
๐คฑ Lactation Safety
Caution; small amounts excreted in breast milk; monitor infant for diarrhea, candidiasis.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination; monitor renal function and hearing.
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for ativak 500mg injection
View AllAlternative brands with exact same active ingredient (Amikacin (500mg)):
-
micin injectionFDC Ltd โน8.75 86.9% CHEAPER
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amikop 500mg injectionKopran Ltd โน9.56 85.7% CHEAPER
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cachmik 500mg injectionCachet Pharmaceuticals Pvt Ltd โน10.62 84.1% CHEAPER
-
zoftamic 500mg injectionElder Pharmaceuticals Ltd โน10.62 84.1% CHEAPER
-
amipic 500mg injectionPCI Pharmaceuticals โน11.25 83.2% CHEAPER
-
amikacin sulphate 500mg injectionSun Pharmaceutical Industries Ltd โน11.87 82.3% CHEAPER
-
m cin 500mg injectionParenteral Drugs India Ltd โน12.02 82.1% CHEAPER
-
unimika 500mg injectionTorrent Pharmaceuticals Ltd โน14.15 78.9% CHEAPER
-
amtop 500mg injectionInd Swift Laboratories Ltd โน15.00 77.6% CHEAPER
-
amikas 500mg injectionChandra Bhagat Pharma Pvt Ltd โน15.00 77.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.