amikop 500mg injection
What is amikop 500mg injection used for?
This medicine contains Amikacin (500mg) and is used to treat OPHTHAL. Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis.. Always consult your doctor before use.
- Generic Name: Amikacin
- Manufacturer: Kopran Ltd
- Form: Allopathy
- Pregnancy Category: Category D
- Prescription Required: Yes
💊 amikop 500mg injection Uses & Benefits
Serious Gram-negative infections (sepsis, pneumonia, complicated UTI, intra-abdominal infections); adjunct in tuberculosis; neonatal sepsis.
Off-label uses: Brucellosis, Plague, Tularemia
📋 Drug Information
| Generic Name(s) | Amikacin |
| Brand Name | Amikacin Sulphate 500mg Injection |
| Manufacturer | Kopran Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Aminoglycosides |
| Route of Administration | Intramuscular, Intravenous |
| Storage | Store at 20-25°C; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis.
Mechanism Steps
💡 How to Take amikop 500mg injection
Follow your doctor's prescription exactly.
⚠️ Side Effects of amikop 500mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade, respiratory depression |
| Cisplatin | Major | Increased nephrotoxicity and ototoxicity |
| Loop diuretics | Major | Increased ototoxicity |
| Vancomycin | Major | Increased nephrotoxicity |
| Penicillins | Moderate | Synergistic antibacterial effect |
| NSAIDs | Moderate | Increased nephrotoxicity risk |
🚨 Major Interactions
- Neuromuscular blocking agents
- Other aminoglycosides
- Cisplatin
- Loop diuretics
- Vancomycin
⚡ Moderate Interactions
- Penicillins (synergy)
- Cephalosporins
- NSAIDs
- Methoxyflurane
🍷 Alcohol Interaction
No known interaction.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to amikacin or other aminoglycosides; myasthenia gravis; pre-existing severe renal impairment.
🤱 Lactation Safety
Caution; small amounts excreted in breast milk; monitor infant for diarrhea, candidiasis.
💊 Overdose Management
Supportive care; hemodialysis may enhance elimination; monitor renal function and hearing.
⏰ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.
🔄 Substitutes for amikop 500mg injection
View AllAlternative brands with exact same active ingredient:
-
micin injectionFDC Ltd ₹8.75 8.5% CHEAPER
-
cachmik 500mg injectionCachet Pharmaceuticals Pvt Ltd ₹10.62 11.1% COSTLIER
-
zoftamic 500mg injectionElder Pharmaceuticals Ltd ₹10.62 11.1% COSTLIER
-
amipic 500mg injectionPCI Pharmaceuticals ₹11.25 17.7% COSTLIER
-
amikacin sulphate 500mg injectionSun Pharmaceutical Industries Ltd ₹11.87 24.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.