Atipam 1mg Tablet - Uses, Price, Side Effects
What is atipam 1mg tablet used for?
Atipam 1mg Tablet contains Lorazepam, a benzodiazepine used to treat anxiety disorders and insomnia. It works by enhancing the effect of GABA, a natural chemical in the brain that promotes calmness and relaxation. It is typically taken 2-3 times daily as prescribed by a doctor.
- Generic Name: Lorazepam
- Manufacturer: Ind Swift Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ atipam 1mg tablet Uses & Benefits
Anxiety disorders, Insomnia (short-term), Preoperative sedation, Status epilepticus (IV), Alcohol withdrawal syndrome
Off-label uses: Chemotherapy-induced nausea and vomiting, Catatonia, Rapid eye movement sleep behavior disorder
๐ Drug Information
| Generic Name(s) | Lorazepam |
| Brand Name | Ativan |
| Manufacturer | Ind Swift Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Benzodiazepines |
| Route of Administration | Oral, intravenous, intramuscular |
| Storage | Store at room temperature (20-25ยฐC) away from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Enhances the inhibitory effect of GABA by binding to benzodiazepine receptors on GABA-A receptors, increasing chloride ion influx and hyperpolarizing neurons.
Mechanism Steps
๐ก How to Take atipam 1mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of atipam 1mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Ataxia
- Weakness
- Blurred vision
- Sedation
๐จ Serious Side Effects
- Respiratory depression
- Paradoxical reactions (e.g., agitation, aggression)
- Physical dependence and withdrawal
- Seizures (with abrupt discontinuation)
- Anterograde amnesia
โ ๏ธ Rare Side Effects
- Blood dyscrasias (e.g., agranulocytosis)
- Jaundice
- Allergic reactions
- Hypotension
- Urinary retention
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased CNS depression |
| Opioid analgesics | Major | Additive sedation and respiratory depression |
| Valproic acid | Moderate | Increased lorazepam levels |
๐จ Major Interactions
- Opioid analgesics
- Other CNS depressants (e.g., barbiturates, alcohol)
- Sodium oxybate
โก Moderate Interactions
- Antipsychotics
- Antidepressants (e.g., SSRIs, MAOIs)
- Antiepileptics (e.g., valproate)
- Antihistamines
โน๏ธ Minor Interactions
- Caffeine
- Oral contraceptives
- Smoking (may decrease efficacy)
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase absorption; high-fat meals may delay absorption.
๐ท Alcohol Interaction
Avoid alcohol; additive CNS depression and increased risk of sedation, respiratory depression, and impaired psychomotor function.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to lorazepam or any benzodiazepine, Acute narrow-angle glaucoma, Severe respiratory insufficiency, Myasthenia gravis, Sleep apnea syndrome, Severe hepatic impairment
๐ Monitoring Parameters
Respiratory rate, Blood pressure, Heart rate, Level of sedation, Liver function tests (if prolonged use), Renal function (if impaired)
๐คฑ Lactation Safety
Lorazepam is excreted in breast milk; use with caution and monitor infant for sedation and feeding d
๐ Overdose Management
Supportive care; consider flumazenil (benzodiazepine antagonist) but monitor for seizures and arrhythmias.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for atipam 1mg tablet
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Medical Note: Always consult your doctor before switching medications.