asv-zol 40 tablet - Esomeprazole (40mg) medicine

Asv-Zol 40 Tablet - Uses, Price, Side Effects

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๐Ÿญ Asvins Lifecare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is asv-zol 40 tablet used for?

Asv-Zol 40 Tablet contains Esomeprazole 40mg, a proton pump inhibitor (PPI) that reduces stomach acid production. It is used to treat acidity, heartburn, gastroesophageal reflux disease (GERD), and stomach ulcers. It works by blocking the enzyme in the stomach wall that produces acid, providing relief from symptoms and promoting healing.

  • Generic Name: Esomeprazole
  • Manufacturer: Asvins Lifecare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š asv-zol 40 tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (in combination), peptic ulcer disease, prevention of NSAID-induced ulcers.

Off-label uses: Laryngopharyngeal reflux, prevention of stress ulcers in critically ill patients, eosinophilic esophagitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Esomeprazole
Brand NameAdyom 40mg Tablet
ManufacturerAsvins Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached within 1-2 hours. Food may delay absorption but does not affect extent.
DistributionVolume of distribution approximately 16 L; extensively distributed into tissues.
Protein Binding97% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes; major metabolites are hydroxy, desmethyl, and sulfone derivatives.
Half-LifeApproximately 1-1.5 hours in healthy subjects; may be prolonged in hepatic impairment.
ExcretionApproximately 80% excreted as metabolites in urine, the remainder in feces.
BioavailabilityApproximately 64% after a single oral dose; may increase with repeated dosing.
Onset of Action1-4 hours for acid suppression.
Peak Plasma Time1-2 hours.
Duration of ActionUp to 24 hours.

How It Works

Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell.

Mechanism Steps

1Esomeprazole accumulates in the acidic environment of gastric parietal cell canaliculi.
2Protonation occurs to form the active sulfenamide metabolite.
3Active metabolite binds covalently to cysteine residues of the H+/K+-ATPase enzyme.

๐Ÿ’ก How to Take asv-zol 40 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โŒ ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of asv-zol 40 tablet

โœ… Common Side Effects

  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Constipation
  • Flatulence
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • Clostridium difficile-associated diarrhea
  • Bone fracture (hip, wrist, spine)
  • Hypomagnesemia
  • Acute interstitial nephritis
  • Cutaneous lupus erythematosus
  • Vitamin B12 deficiency (long-term)

โš ๏ธ Rare Side Effects

  • Hepatic encephalopathy
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Agranulocytosis
  • Pancreatitis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Clopidogrel Moderate Reduced antiplatelet effect
Methotrexate Major Increased methotrexate toxicity
Warfarin Moderate Increased INR and bleeding risk

๐Ÿšจ Major Interactions

  • Clopidogrel
  • Methotrexate
  • Rilpivirine
  • Atazanavir
  • Nelfinavir
  • Saquinavir
  • Erlotinib
  • Dasatinib
  • Nilotinib
  • Mycophenolate mofetil

โšก Moderate Interactions

  • Warfarin
  • Cilostazol
  • Diazepam
  • Phenytoin
  • Citalopram
  • Escitalopram
  • Ketoconazole
  • Itraconazole
  • Iron salts
  • Digoxin
  • Tacrolimus
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Sucralfate
  • Ampicillin
  • Bisphosphonates
  • Tyrosine kinase inhibitors

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; best taken on an empty stomach at least 1 hour before a meal.

๐Ÿท Alcohol Interaction

No direct interaction; alcohol may exacerbate gastric irritation.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to esomeprazole or substituted benzimidazoles; concomitant use with rilpivirine-containing products.

๐Ÿ“Š Monitoring Parameters

Symptoms of acid reflux, endoscopic healing, serum magnesium levels (with prolonged use), bone mineral density (long-term), liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised; avoid if possible.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote; hemodialysis not effective.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for asv-zol 40 tablet

View All

Alternative brands with exact same active ingredient (Esomeprazole (40mg)):

Medical Note: Always consult your doctor before switching medications.

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