aspofag 40mg injection - Uses, Price, Side Effects & Substitutes
What is aspofag 40mg injection used for?
Adyom 40mg Tablet (Esomeprazole) is used to treat GASTRO INTESTINAL. It contains Esomeprazole (40mg), which Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion b. Always consult your doctor before use. Take as prescribed.
- Generic Name: Esomeprazole
- Manufacturer: Aspo Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aspofag 40mg injection Uses & Benefits
Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (in combination), peptic ulcer disease, prevention of NSAID-induced ulcers.
Off-label uses: Laryngopharyngeal reflux, prevention of stress ulcers in critically ill patients, eosinophilic esophagitis.
๐ Drug Information
| Generic Name(s) | Esomeprazole |
| Brand Name | Adyom 40mg Tablet |
| Manufacturer | Aspo Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton pump inhibitors |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell.
Mechanism Steps
๐ก How to Take aspofag 40mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aspofag 40mg injection
โ Common Side Effects
- Headache
- Abdominal pain
- Nausea
- Diarrhea
- Constipation
- Flatulence
- Dry mouth
๐จ Serious Side Effects
- Clostridium difficile-associated diarrhea
- Bone fracture (hip, wrist, spine)
- Hypomagnesemia
- Acute interstitial nephritis
- Cutaneous lupus erythematosus
- Vitamin B12 deficiency (long-term)
โ ๏ธ Rare Side Effects
- Hepatic encephalopathy
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Agranulocytosis
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Clopidogrel | Major | Reduced clopidogrel activation and antiplatelet effect |
| Methotrexate | Major | Increased methotrexate levels and toxicity |
| Rilpivirine | Major | Decreased rilpivirine absorption and efficacy |
| Atazanavir | Major | Decreased atazanavir absorption |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Cilostazol | Moderate | Increased cilostazol levels |
| Diazepam | Moderate | Increased diazepam levels |
| Phenytoin | Moderate | Increased phenytoin levels |
| Citalopram | Moderate | Increased citalopram levels |
| Ketoconazole | Moderate | Decreased ketoconazole absorption |
| Iron salts | Moderate | Decreased iron absorption |
| Digoxin | Moderate | Increased digoxin levels |
| Sucralfate | Minor | Decreased esomeprazole absorption |
| Ampicillin | Minor | Decreased ampicillin absorption |
๐จ Major Interactions
- Clopidogrel
- Methotrexate
- Rilpivirine
- Atazanavir
- Nelfinavir
- Saquinavir
- Erlotinib
- Dasatinib
- Nilotinib
- Mycophenolate mofetil
โก Moderate Interactions
- Warfarin
- Cilostazol
- Diazepam
- Phenytoin
- Citalopram
- Escitalopram
- Ketoconazole
- Itraconazole
- Iron salts
- Digoxin
- Tacrolimus
- Cyclosporine
โน๏ธ Minor Interactions
- Sucralfate
- Ampicillin
- Bisphosphonates
- Tyrosine kinase inhibitors
๐ฝ๏ธ Food Interactions
Food may delay absorption; best taken on an empty stomach at least 1 hour before a meal.
๐ท Alcohol Interaction
No direct interaction; alcohol may exacerbate gastric irritation.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to esomeprazole or substituted benzimidazoles; concomitant use with rilpivirine-containing products.
๐ Monitoring Parameters
Symptoms of acid reflux, endoscopic healing, serum magnesium levels (with prolonged use), bone mineral density (long-term), liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised; avoid if possible.
๐ Overdose Management
Supportive care; no specific antidote; hemodialysis not effective.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for aspofag 40mg injection
View AllAlternative brands with exact same active ingredient (Esomeprazole (40mg)):
-
esomez 40mg tabletDr Reddy's Laboratories Ltd โน8.08 92.5% CHEAPER
-
eszole tabletOlcare Laboratories โน13.47 87.5% CHEAPER
-
ezimoz s 40mg tabletDR Best pharmaceuticals Pvt Ltd โน17.81 83.5% CHEAPER
-
esotrax 40mg tabletCadila Pharmaceuticals Ltd โน19.92 81.5% CHEAPER
-
davaindia esomeprazole 40mg tabletDavaindia Generic Pharmacy โน20.00 81.4% CHEAPER
-
eszone 40mg tabletZeelab Pharmacy Pvt Ltd โน22.50 79.1% CHEAPER
-
somifiz 40 mg tabletMankind Pharma Ltd โน23.23 78.5% CHEAPER
-
espearl 40mg tabletRichie Laboratories Ltd โน25.31 76.5% CHEAPER
-
ecorest 40mg tabletCentaur Pharmaceuticals Pvt Ltd โน25.33 76.5% CHEAPER
-
albesom 40mg tabletSanify Healthcare Pvt Ltd โน26.58 75.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.