asginase 10000iu injection
What is asginase 10000iu injection used for?
Asginase (Asparaginase) is used to treat ANTI NEOPLASTICS. It contains Asparaginase (10000IU), which Depletes extracellular asparagine by catalyzing its conversion to aspartic acid . Always consult your doctor before use. Take as prescribed.
- Generic Name: Asparaginase
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ asginase 10000iu injection Uses & Benefits
Acute lymphoblastic leukemia (ALL), especially in combination chemotherapy.
Off-label uses: Some lymphomas, acute myeloid leukemia (limited data).
๐ Drug Information
| Generic Name(s) | Asparaginase |
| Brand Name | Asginase |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Anticancer-others |
| Route of Administration | Intravenous or intramuscular injection. |
| Storage | Store at 2-8ยฐC; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Depletes extracellular asparagine by catalyzing its conversion to aspartic acid and ammonia, inhibiting protein synthesis in leukemic cells.
Mechanism Steps
๐ก How to Take asginase 10000iu injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of asginase 10000iu injection
โ Common Side Effects
- Nausea
- Vomiting
- Fever
- Chills
- Anorexia
๐จ Serious Side Effects
- Pancreatitis
- Thrombosis
- Hemorrhage
- Hepatotoxicity
- Allergic reactions
โ ๏ธ Rare Side Effects
- Hyperglycemia
- Seizures
- Encephalopathy
- Renal failure
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased toxicity |
| Vincristine | Major | Increased neurotoxicity |
| Prednisone | Major | Increased hyperglycemia |
| Warfarin | Moderate | Altered anticoagulation |
| Heparin | Moderate | Increased bleeding risk |
| Oral contraceptives | Moderate | Reduced efficacy |
| Allopurinol | Minor | Increased uric acid levels |
| Loop diuretics | Minor | Electrolyte imbalance |
๐จ Major Interactions
- Methotrexate
- Vincristine
- Prednisone
โก Moderate Interactions
- Warfarin
- Heparin
- Oral contraceptives
โน๏ธ Minor Interactions
- Allopurinol
- Loop diuretics
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to increased hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to asparaginase, pancreatitis, history of thrombosis or bleeding disorders.
๐ Monitoring Parameters
Liver function tests, serum amylase, coagulation profile, blood glucose, uric acid.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor for pancreatitis, coagulopathy, and hepatotoxicity.
โฐ Missed Dose
Administer as soon as possible; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for asginase 10000iu injection
View AllAlternative brands with exact same active ingredient (Asparaginase (10000IU)):
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l-aspase 10000iu injectionMiracalus Pharma Pvt Ltd โน1,500.00 4.1% CHEAPER
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oncoginase 10000iu injectionChandra Bhagat Pharma Pvt Ltd โน1,529.00 2.2% CHEAPER
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asparshil 10000iu injectionShilpa Medicare Ltd โน1,582.00 1.2% COSTLIER
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onconase 10000iu injectionUnited Biotech Pvt Ltd โน1,595.00 2% COSTLIER
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bionase 10000iu injectionBiochem Pharmaceutical Industries โน1,680.66 7.5% COSTLIER
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l ginase 10000iu injectionGetwell Oncology Pvt Ltd โน1,788.00 14.3% COSTLIER
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lagicad 10000iu injectionCadila Pharmaceuticals Ltd โน1,793.12 14.7% COSTLIER
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celginase 10000iu injectionCelon Laboratories Ltd โน1,800.00 15.1% COSTLIER
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l-aspatero 10000iu injectionHetero Drugs Ltd โน1,800.00 15.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.