ascolex 5mg syrup - Sodium Picosulfate (5mg) medicine

Ascolex 5mg Syrup - Uses, Price, Side Effects

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🏭 Ridhima Biocare 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is ascolex 5mg syrup used for?

Ascolex 5mg Syrup contains Sodium Picosulfate, a stimulant laxative used for short-term relief of constipation. It works by stimulating the bowel muscles to promote a bowel movement. It is typically taken at bedtime for a morning bowel movement. Always use under medical supervision.

  • Generic Name: Sodium Picosulfate
  • Manufacturer: Ridhima Biocare
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ascolex 5mg syrup Uses & Benefits

Constipation, bowel evacuation before diagnostic procedures or surgery.

Off-label uses: Hepatic encephalopathy (as part of bowel cleansing)

📋 Drug Information

Generic Name(s)Sodium Picosulfate
Brand NameAlpicno 5mg/5ml Syrup
ManufacturerRidhima Biocare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassStimulant laxatives/purgative
Route of AdministrationOral
StorageStore at room temperature (15-30°C), protect from light.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; minimal systemic absorption due to local action in colon.
DistributionMinimal systemic distribution; acts locally in the colon.
Protein BindingNot applicable due to minimal systemic absorption.
MetabolismHydrolyzed by colonic bacteria to active metabolite (bis-(p-hydroxyphenyl)-pyridyl-2-methane).
Half-LifeNot clinically relevant due to local action.
ExcretionPrimarily fecal as active metabolite.
BioavailabilityLow systemic bioavailability due to local action.
Onset of Action6-12 hours
Peak Plasma TimeNot applicable; local action.
Duration of ActionVariable; typically produces bowel movement within 6-12 hours.

How It Works

Stimulates peristalsis by acting on the colonic mucosa to increase fluid secretion and motility.

Mechanism Steps

1Oral administration reaches colon unchanged.
2Hydrolyzed by colonic bacteria to active metabolite.
3Active metabolite stimulates colonic mucosa.
4Increases fluid secretion and peristalsis.
5Results in laxation within 6-12 hours.

💡 How to Take ascolex 5mg syrup

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of ascolex 5mg syrup

✅ Common Side Effects

Abdominal cramps
Diarrhea
Nausea

🚨 Serious Side Effects

Electrolyte imbalance
Dehydration
Syncope

⚠️ Rare Side Effects

Allergic reactions
Colonic ischemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Diuretics Moderate Increased risk of electrolyte imbalance
Digoxin Moderate Increased risk of digoxin toxicity due to electrolyte disturbances
Corticosteroids Moderate Increased risk of electrolyte imbalance

🚨 Major Interactions

  • Diuretics
  • Corticosteroids

⚡ Moderate Interactions

  • Cardiac glycosides
  • Antiarrhythmics

🍷 Alcohol Interaction

No significant interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Intestinal obstruction, acute surgical abdomen, appendicitis, severe dehydration, hypersensitivity.

🤱 Lactation Safety

Safety not established; use with caution.

💊 Overdose Management

Induce vomiting or gastric lavage; monitor electrolytes and fluid balance; symptomatic treatment.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🔄 Substitutes for ascolex 5mg syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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