artzom 60mg injection - Uses, Price, Side Effects & Substitutes
What is artzom 60mg injection used for?
Azunate (Artesunate) is used to treat ANTI MALARIALS. It contains Artesunate (60mg), which Artesunate is a prodrug that is converted to dihydroartemisinin, which generates. Always consult your doctor before use. Take as prescribed.
- Generic Name: Artesunate
- Manufacturer: Zoom Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ artzom 60mg injection Uses & Benefits
Severe malaria (IV/IM); uncomplicated malaria (oral combination therapy); multidrug-resistant malaria.
Off-label uses: Babesiosis (in combination with other agents); some autoimmune diseases (investigational).
๐ Drug Information
| Generic Name(s) | Artesunate |
| Brand Name | Azunate |
| Manufacturer | Zoom Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial- Artemisinin and derivatives |
| Route of Administration | Intravenous, intramuscular, oral. |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Artesunate is a prodrug that is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.
Mechanism Steps
๐ก How to Take artzom 60mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of artzom 60mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Headache
- Dizziness
- Fever
๐จ Serious Side Effects
- Severe allergic reactions
- Hemolytic anemia
- QT prolongation
- Seizures
โ ๏ธ Rare Side Effects
- Neurotoxicity (ataxia, tremors)
- Hepatitis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Mefloquine | Major | Increased risk of seizures and QT prolongation |
| Rifampin | Major | Reduced artesunate efficacy due to enzyme induction |
| Carbamazepine | Major | Decreased artesunate levels |
| Phenytoin | Major | Decreased artesunate levels |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Grapefruit juice | Minor | Possible slight increase in artesunate levels |
๐จ Major Interactions
- Mefloquine
- Rifampin
- Carbamazepine
- Phenytoin
โก Moderate Interactions
- Warfarin
- Anticoagulants
- Antiplatelet agents
โน๏ธ Minor Interactions
- Grapefruit juice
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions; absorption may be slightly delayed with high-fat meals.
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to artesunate or any component; first trimester of pregnancy (unless no alternative).
๐ Monitoring Parameters
Parasitemia levels, complete blood count, liver function tests, ECG if co-administered with QT-prolonging drugs.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; caution advised.
๐ Overdose Management
Supportive care; no specific antidote. Monitor for neurotoxicity (rare).
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for artzom 60mg injection
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Medical Note: Always consult your doctor before switching medications.