artivarin 60mg injection - Artesunate (60mg) medicine

Artivarin 60mg Injection - Uses, Price, Side Effects

4.3 (14 reviews)
Artesunate (60mg)
๐Ÿญ German Remedies ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is artivarin 60mg injection used for?

Artivarin 60mg Injection contains Artesunate, an antimalarial used for severe malaria. It works by killing the malaria parasite in the blood. It is given as an injection in a hospital setting for rapid action. Always use under medical supervision.

  • Generic Name: Artesunate
  • Manufacturer: German Remedies
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š artivarin 60mg injection Uses & Benefits

Severe malaria (IV/IM); uncomplicated malaria (oral combination therapy); multidrug-resistant malaria.

Off-label uses: Babesiosis (in combination with other agents); some autoimmune diseases (investigational).

๐Ÿ“‹ Drug Information

Generic Name(s)Artesunate
Brand NameAzunate
ManufacturerGerman Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationIntravenous, intramuscular, oral.
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular or intravenous administration; oral absorption is rapid but with high first-pass metabolism.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 81-93% bound to plasma proteins.
MetabolismPrimarily hydrolyzed to dihydroartemisinin (active metabolite) by esterases in the liver and blood.
Half-LifeArtesunate: ~2-3 minutes; Dihydroartemisinin: ~45-60 minutes.
ExcretionPrimarily via urine (as metabolites); small amount in feces.
BioavailabilityIntravenous: 100%; Intramuscular: ~85-90%; Oral: ~40-60% due to first-pass metabolism.
Onset of ActionRapid (within 30 minutes for IV/IM).
Peak Plasma TimeArtesunate: 5-15 minutes; Dihydroartemisinin: 1-2 hours.
Duration of ActionShort; requires multiple doses.

How It Works

Artesunate is a prodrug that is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.

Mechanism Steps

1Artesunate is administered and rapidly converted to dihydroartemisinin (DHA) by esterases.
2DHA enters the parasite and interacts with heme (from hemoglobin digestion).
3The iron in heme cleaves the endoperoxide bridge of DHA, generating free radicals.

๐Ÿ’ก How to Take artivarin 60mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of artivarin 60mg injection

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Dizziness
  • Fever

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions
  • Hemolytic anemia
  • QT prolongation
  • Seizures

โš ๏ธ Rare Side Effects

  • Neurotoxicity (ataxia, tremors)
  • Hepatitis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Mefloquine Moderate Increased risk of seizures
Warfarin Major Decreased anticoagulant effect

๐Ÿšจ Major Interactions

  • Mefloquine
  • Rifampin
  • Carbamazepine
  • Phenytoin

โšก Moderate Interactions

  • Warfarin
  • Anticoagulants
  • Antiplatelet agents

โ„น๏ธ Minor Interactions

  • Grapefruit juice
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; absorption may be slightly delayed with high-fat meals.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to artesunate or any component; first trimester of pregnancy (unless no alternative).

๐Ÿ“Š Monitoring Parameters

Parasitemia levels, complete blood count, liver function tests, ECG if co-administered with QT-prolonging drugs.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote. Monitor for neurotoxicity (rare).

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for artivarin 60mg injection

View All

Alternative brands with exact same active ingredient (Artesunate (60mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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