Artisid 50mg Capsule - Uses, Price, Side Effects
What is artisid 50mg capsule used for?
Artisid 50mg capsule contains Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, and other inflammatory conditions. It works by blocking the production of prostaglandins, substances that cause pain and inflammation.
- Generic Name: Indomethacin
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ artisid 50mg capsule Uses & Benefits
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gouty arthritis, bursitis, tendinitis, patent ductus arteriosus in neonates.
Off-label uses: Prevention of preterm labor, closure of patent ductus arteriosus in preterm infants, treatment of Bartter syndrome.
๐ Drug Information
| Generic Name(s) | Indomethacin |
| Brand Name | Artisid 50mg Capsule |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Non-selective inhibition of cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take artisid 50mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of artisid 50mg capsule
โ Common Side Effects
- Headache
- dizziness
- nausea
- vomiting
- dyspepsia
- abdominal pain
- constipation
- diarrhea
- heartburn
๐จ Serious Side Effects
- GI bleeding
- peptic ulcer
- perforation
- renal failure
- hypertension
- heart failure
- thrombotic events
- anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hepatitis
- pancreatitis
- agranulocytosis
- aplastic anemia
- hemolytic anemia
- aseptic meningitis
- psychotic reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased risk of GI ulceration and bleeding |
| Lithium | Major | Increased lithium levels and toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect; increased renal impairment risk |
| Diuretics | Major | Reduced diuretic effect; increased risk of renal failure |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased risk of GI ulceration |
| SSRIs | Moderate | Increased bleeding risk |
| Digoxin | Moderate | Increased digoxin levels |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Antacids | Minor | Reduced absorption of indomethacin |
| Cholestyramine | Minor | Reduced absorption of indomethacin |
๐จ Major Interactions
- Warfarin
- Aspirin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
โก Moderate Interactions
- Anticoagulants
- Corticosteroids
- SSRIs
- Digoxin
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to indomethacin or other NSAIDs; history of asthma, urticaria, or allergic reactions to NSAIDs; active peptic ulcer disease; severe renal or hepatic impairment; third trimester of pregnancy; perioperative pain in CABG surgery.
๐ Monitoring Parameters
Renal function, hepatic function, blood pressure, CBC, signs of GI bleeding, serum electrolytes.
๐คฑ Lactation Safety
Excreted in breast milk; avoid use due to potential adverse effects in infant.
๐ Overdose Management
Symptomatic and supportive care; induce emesis or gastric lavage; activated charcoal; monitor for GI bleeding, renal failure, and CNS depression.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for artisid 50mg capsule
View AllAlternative brands with exact same active ingredient (Indomethacin (50mg)):
-
inmecin 50mg capsuleSterkem Pharma Pvt Ltd โน60.00 93.1% COSTLIER
-
inmecin 50mg tabletSterkem Pharma Pvt Ltd โน80.00 157.4% COSTLIER
-
inmeth suppositoriesHetero Healthcare Limited โน425.00 1267.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.