arth 60mg injection - Artesunate (60mg) medicine

Arth 60mg Injection - Uses, Price, Side Effects

4.7 (12 reviews)

Artesunate (60mg)

🏭 Plus India 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is arth 60mg injection used for?

Arth 60mg Injection contains Artesunate, an antimalarial used for severe malaria. It works by killing the malaria parasite in the blood. It is administered intravenously or intramuscularly under medical supervision.

Generic Name: Artesunate
Manufacturer: Plus India
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 arth 60mg injection Uses & Benefits

Severe malaria (IV/IM); uncomplicated malaria (oral combination therapy); multidrug-resistant malaria.

Off-label uses: Babesiosis (in combination with other agents); some autoimmune diseases (investigational).

📋 Drug Information

Generic Name(s)	Artesunate
Brand Name	Azunate
Manufacturer	Plus India
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI MALARIALS
Action Class	Antimalarial- Artemisinin and derivatives
Route of Administration	Intravenous, intramuscular, oral.
Storage	Store at room temperature (20-25°C); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular or intravenous administration; oral absorption is rapid but with high first-pass metabolism.

DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.

Protein BindingApproximately 81-93% bound to plasma proteins.

MetabolismPrimarily hydrolyzed to dihydroartemisinin (active metabolite) by esterases in the liver and blood.

Half-LifeArtesunate: ~2-3 minutes; Dihydroartemisinin: ~45-60 minutes.

ExcretionPrimarily via urine (as metabolites); small amount in feces.

BioavailabilityIntravenous: 100%; Intramuscular: ~85-90%; Oral: ~40-60% due to first-pass metabolism.

Onset of ActionRapid (within 30 minutes for IV/IM).

Peak Plasma TimeArtesunate: 5-15 minutes; Dihydroartemisinin: 1-2 hours.

Duration of ActionShort; requires multiple doses.

How It Works

Artesunate is a prodrug that is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.

Mechanism Steps

1Artesunate is administered and rapidly converted to dihydroartemisinin (DHA) by esterases.

2DHA enters the parasite and interacts with heme (from hemoglobin digestion).

3The iron in heme cleaves the endoperoxide bridge of DHA, generating free radicals.

💡 How to Take arth 60mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of arth 60mg injection

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Headache
Dizziness
Fever

🚨 Serious Side Effects

Severe allergic reactions
Hemolytic anemia
QT prolongation
Seizures

⚠️ Rare Side Effects

Neurotoxicity (ataxia, tremors)
Hepatitis
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Mefloquine	Moderate	Increased risk of QT prolongation
Warfarin	Major	Increased anticoagulant effect

🚨 Major Interactions

Mefloquine
Rifampin
Carbamazepine
Phenytoin

⚡ Moderate Interactions

Warfarin
Anticoagulants
Antiplatelet agents

ℹ️ Minor Interactions

Grapefruit juice
Cimetidine

🍽️ Food Interactions

No significant food interactions; absorption may be slightly delayed with high-fat meals.

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to artesunate or any component; first trimester of pregnancy (unless no alternative).

📊 Monitoring Parameters

Parasitemia levels, complete blood count, liver function tests, ECG if co-administered with QT-prolonging drugs.

🤱 Lactation Safety

Excreted in breast milk in small amounts; caution advised.

💊 Overdose Management

Supportive care; no specific antidote. Monitor for neurotoxicity (rare).

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for arth 60mg injection

View All

Alternative brands with exact same active ingredient (Artesunate (60mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026