Arte Plus AB 150mg Injection - Uses, Price, Side Effects
What is arte plus ab 150mg injection used for?
Arte Plus AB 150mg Injection contains Arteether, an antimalarial drug used to treat severe falciparum malaria. It works by killing the malaria parasite in the blood. It is administered by a healthcare professional and is effective against chloroquine-resistant strains. Common side effects include injection site pain, headache, and nausea.
- Generic Name: Arteether
- Manufacturer: Zydus Cadila
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arte plus ab 150mg injection Uses & Benefits
Treatment of uncomplicated and severe falciparum malaria; chloroquine-resistant malaria.
Off-label uses: Babesiosis (limited evidence); autoimmune diseases (not recommended).
๐ Drug Information
| Generic Name(s) | Arteether |
| Brand Name | Artisun 150mg Injection |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial- Artemisinin and derivatives |
| Route of Administration | Intramuscular injection only. |
| Storage | Store at 20-25ยฐC; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Arteether is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.
Mechanism Steps
๐ก How to Take arte plus ab 150mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of arte plus ab 150mg injection
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Vomiting
- Abdominal pain
- Injection site pain
๐จ Serious Side Effects
- QTc prolongation
- Severe hemolysis (in G6PD deficiency)
- Hepatotoxicity
- Allergic reactions
โ ๏ธ Rare Side Effects
- Neurotoxicity (ataxia, tremors)
- Hemolytic anemia
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Mefloquine | Major | Increased risk of QT prolongation |
| Halofantrine | Major | Increased risk of cardiotoxicity |
| Warfarin | Moderate | Altered anticoagulant effect |
๐จ Major Interactions
- Mefloquine
- Quinine
- Halofantrine
โก Moderate Interactions
- CYP2A6 inhibitors (e.g., ketoconazole)
- CYP2A6 inducers (e.g., rifampin)
โน๏ธ Minor Interactions
- Anticoagulants (e.g., warfarin)
- Antiepileptics (e.g., carbamazepine)
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to arteether or artemisinin derivatives; severe hepatic impairment.
๐ Monitoring Parameters
Parasite count, hemoglobin, liver function tests, ECG if co-administered with cardiotoxic drugs.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised; discontinue breastfeeding or drug.
๐ Overdose Management
Symptomatic and supportive treatment; no specific antidote; monitor ECG and liver function.
โฐ Missed Dose
Administer as soon as remembered; do not double dose; maintain dosing interval.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for arte plus ab 150mg injection
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Medical Note: Always consult your doctor before switching medications.