Arsin Forte 80mg/480mg Tablet - Uses, Price, Side Effects
What is arsin forte 80mg/480mg tablet used for?
Arsin Forte 80mg/480mg Tablet is a combination of Artemether and Lumefantrine, used to treat uncomplicated malaria caused by Plasmodium falciparum. Artemether rapidly reduces the parasite count, while Lumefantrine eliminates the remaining parasites, preventing relapse. It is taken twice daily for 3 days with fatty food for better absorption.
- Generic Name: Artemether + Lumefantrine
- Manufacturer: Tuttsan Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arsin forte 80mg/480mg tablet Uses & Benefits
Uncomplicated falciparum malaria, chloroquine-resistant malaria.
Off-label uses: Severe malaria (IV artemether not available), babesiosis.
๐ Drug Information
| Generic Name(s) | Artemether + Lumefantrine |
| Brand Name | Artether L |
| Manufacturer | Tuttsan Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Artemether: Produces free radicals damaging parasite membranes; Lumefantrine: Inhibits heme polymerization.
Mechanism Steps
๐ก How to Take arsin forte 80mg/480mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of arsin forte 80mg/480mg tablet
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
๐จ Serious Side Effects
- QT prolongation
- Cardiac arrhythmias
- Severe allergic reactions
- Hemolytic anemia (G6PD deficiency)
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Neurotoxicity (high doses)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| CYP3A4 inhibitors (e.g., ketoconazole) | Moderate | Increased artemether levels |
| CYP3A4 inducers (e.g., rifampin) | Moderate | Decreased artemether levels |
| Antacids | Minor | Reduced absorption of lumefantrine |
๐จ Major Interactions
- CYP3A4 inducers (rifampin, carbamazepine)
- CYP3A4 inhibitors (ketoconazole, ritonavir)
- Antiarrhythmics (amiodarone, quinidine)
โก Moderate Interactions
- Oral contraceptives
- Antipsychotics
- Macrolide antibiotics
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
๐ฝ๏ธ Food Interactions
Enhanced absorption with fatty foods; avoid grapefruit juice.
๐ท Alcohol Interaction
No significant interaction reported.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, known QT prolongation, concomitant with CYP3A4 inducers.
๐ Monitoring Parameters
ECG (QT interval), parasitemia, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Symptomatic and supportive; monitor ECG for QT prolongation.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip and resume schedule.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.