aronim d 10mg/100mg tablet - Dicyclomine (10mg) + Nimesulide (100mg) medicine

aronim d 10mg/100mg tablet

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๐Ÿญ Alpha Aromatic Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 5, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 05, 2026

What is aronim d 10mg/100mg tablet used for?

Avospas 20mg/100mg Tablet (Dicyclomine + Nimesulide) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (10mg) + Nimesulide (100mg), which Dicyclomine: Antimuscarinic; Nimesulide: COX-2 selective inhibition. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Dicyclomine + Nimesulide
  • Manufacturer: Alpha Aromatic Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š aronim d 10mg/100mg tablet Uses & Benefits

Irritable bowel syndrome, dysmenorrhea, gastrointestinal spasms

Off-label uses: Not well established

๐Ÿ“‹ Drug Information

Generic Name(s)Dicyclomine + Nimesulide
Brand NameAvospas 20mg/100mg Tablet
ManufacturerAlpha Aromatic Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protected from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingDicyclomine: ~90%; Nimesulide: >99%
MetabolismHepatic (CYP2C9 for nimesulide)
Half-LifeDicyclomine: 2-4 hours; Nimesulide: 2-5 hours
ExcretionRenal (urine) and fecal
BioavailabilityDicyclomine: ~70%; Nimesulide: ~100%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours

How It Works

Dicyclomine: Antimuscarinic; Nimesulide: COX-2 selective inhibition

Mechanism Steps

1Dicyclomine blocks muscarinic receptors in GI smooth muscle, reducing spasms
2Nimesulide selectively inhibits COX-2 enzyme, decreasing prostaglandin synthesis
3Reduced prostaglandins lead to decreased inflammation and pain

๐Ÿ’ก How to Take aronim d 10mg/100mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aronim d 10mg/100mg tablet

โœ… Common Side Effects

  • Dry mouth
  • Dizziness
  • Drowsiness
  • Nausea
  • Diarrhea
  • Abdominal pain

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Anaphylaxis
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Pancreatitis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulcer risk
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Corticosteroids Moderate Increased GI ulcer risk
SSRIs Moderate Increased bleeding risk
Antacids Minor Reduced absorption of nimesulide
Cimetidine Minor Increased nimesulide levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Anticoagulants
  • Aspirin

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • SSRIs

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Avoid high-fat meals; may delay absorption

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, pregnancy (third trimester), history of asthma, children <12 years

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, GI symptoms, blood pressure

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, symptomatic treatment

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 05, 2026

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