arma mf tablet - Drotaverine (80mg) + Mefenamic Acid (250mg) medicine

Arma MF Tablet - Uses, Price, Side Effects

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๐Ÿญ Archmed Biotech Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is arma mf tablet used for?

Arma MF Tablet is a combination medicine containing Drotaverine (80mg) and Mefenamic Acid (250mg). It is used to relieve abdominal pain and cramps caused by gastrointestinal spasms, menstrual cramps, and other smooth muscle spasms. Drotaverine relaxes the muscles, while Mefenamic Acid reduces pain and inflammation. Take it as prescribed, usually with food to avoid stomach upset.

  • Generic Name: Drotaverine + Mefenamic Acid
  • Manufacturer: Archmed Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š arma mf tablet Uses & Benefits

Smooth muscle spasms associated with GI, biliary, or urinary tract disorders; dysmenorrhea

Off-label uses: Renal colic, biliary colic, migraine (limited evidence)

๐Ÿ“‹ Drug Information

Generic Name(s)Drotaverine + Mefenamic Acid
Brand NameAlmefkem-D Tablet
ManufacturerArchmed Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributed widely in body tissues
Protein BindingDrotaverine: 95-98%; Mefenamic Acid: 90-98%
MetabolismDrotaverine: Hepatic; Mefenamic Acid: Hepatic (CYP2C9)
Half-LifeDrotaverine: 7-12 hours; Mefenamic Acid: 2-4 hours
ExcretionDrotaverine: Renal and fecal; Mefenamic Acid: Renal (primarily) and fecal
BioavailabilityDrotaverine: ~100%; Mefenamic Acid: ~90%
Onset of ActionDrotaverine: 30-60 min; Mefenamic Acid: 1-2 hours
Peak Plasma TimeDrotaverine: 1-2 hours; Mefenamic Acid: 2-4 hours
Duration of ActionDrotaverine: 4-6 hours; Mefenamic Acid: 6-8 hours

How It Works

Drotaverine inhibits phosphodiesterase IV, causing smooth muscle relaxation; Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Drotaverine inhibits phosphodiesterase IV, increasing cAMP levels in smooth muscle cells.
2Increased cAMP leads to relaxation of smooth muscle via activation of protein kinase A.
3Mefenamic acid inhibits cyclooxygenase (COX-1 and COX-2) enzymes.

๐Ÿ’ก How to Take arma mf tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of arma mf tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Drowsiness
  • Dry mouth
  • Diarrhea
  • Constipation

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Bone marrow suppression

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Hepatic necrosis
  • Agranulocytosis
  • Thrombocytopenia
  • Aplastic anemia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium toxicity risk
ACE inhibitors Minor Reduced antihypertensive effect

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • ACE inhibitors
  • Diuretics

โšก Moderate Interactions

  • Anticoagulants
  • Antiplatelets
  • Corticosteroids
  • SSRIs
  • Alcohol

โ„น๏ธ Minor Interactions

  • Antacids
  • Digoxin
  • Phenytoin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; avoid high-fat meals.

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, asthma, history of NSAID-induced reactions, third trimester pregnancy

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, blood pressure, signs of GI bleeding

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; monitor for CNS depression, seizures, renal failure

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

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