arm q injection - Quinine (NA) medicine

Arm Q Injection: Complete Medicine Guide

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🏭 Sanjivani Parenteral Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for the treatment of severe malaria when used under medical supervision.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe low blood sugar with sweating, confusion, or fainting.
  • Difficulty breathing or swelling of the face, lips, or throat.
  • Chest pain, palpitations, or fainting.
  • Dark urine, yellow eyes or skin, or unusual tiredness.
  • Severe headache with blurred vision or ringing in the ears.
  • Unusual bleeding or bruising.
  • A big drop in urine output or swelling of the body.

If experiencing severe symptoms, call emergency services immediately.

What is arm q injection used for?

This medicine is an intramuscular injection of quinine used to treat severe malaria when a patient cannot take oral medicines. It is given only by a healthcare professional and works by killing malaria parasites in the blood.

  • Generic Name: Quinine
  • Manufacturer: Sanjivani Parenteral Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 arm q injection के बारे में (Hindi Summary)

उपयोग: यह दवा क्विनाइन का इंट्रामस्क्युलर इंजेक्शन है, जिसका उपयोग गंभीर मलेरिया के इलाज के लिए किया जाता है। जब मरीज मुंह से दवा नहीं ले पाता, जैसे बार-बार उल्टी होना, बेहोशी या बहुत कमजोरी, तब यह इंजेक्शन दिया जाता है। यह मलेरिया के परजीवी को खून में मारता है और बुखार, ठंड लगना और शरीर दर्द जैसे लक्षणों को कम करने में मदद करता है। यह दवा सिर्फ डॉक्टर या प्रशिक्षित नर्स द्वारा ही लगाई जाती है। घर पर खुद इंजेक्शन न लगाएं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन, जी मिचलाना, उल्टी, सिरदर्द, चक्कर आना, धुंधला दिखना और कान में घंटी बजने जैसी आवाज आना शामिल है। कुछ गंभीर दुष्प्रभाव भी हो सकते हैं, जैसे ब्लड शुगर का बहुत कम हो जाना, गंभीर एलर्जी, दिल की धड़कन में गड़बड़ी, खून की कमी, किडनी पर असर और सुनने या दिखने में गंभीर बदलाव। अगर कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा सिर्फ अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही लगाई जानी चाहिए। खुद से इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दिल की दवाएं, खून पतला करने वाली दवाएं और मधुमेह की दवाएं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर को जरूर बताएं। इलाज के दौरान शराब न लें। तब तक गाड़ी न चलाएं जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 arm q injection Uses & Benefits

[{"condition":"Severe or complicated malaria","description":"Used as an intramuscular treatment for severe malaria caused by Plasmodium falciparum when oral therapy is not possible.","evidence":"Well-established"},{"condition":"Malaria when oral treatment cannot be taken","description":"Given when a patient is vomiting, unconscious, or unable to swallow oral antimalarial medicines.","evidence":"Well-established"},{"condition":"Cerebral malaria","description":"May be used as part of management when malaria affects the brain and the patient cannot take oral medicines.","evidence":"Established"}]

Off-label uses: [{"condition":"Muscle cramps","description":"Quinine has sometimes been used for night-time leg cramps, but this is not recommended because of safety concerns and is not an approved use.","evidence":"Limited and not recommended"},{"condition":"Babesiosis","description":"Quinine has been used in combination with other medicines for babesiosis in some settings, but this is a specialist decision.","evidence":"Limited"}]

Primary treatment for: Severe malaria

Also treats: Complicated malaria, Cerebral malaria

📋 Drug Information

Generic Name(s)Quinine
Brand NameArm Q Injection
ManufacturerSanjivani Parenteral Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- others
Route of AdministrationIntramuscular injection, given by a healthcare professional into a large muscle such as the buttock or thigh
StorageStore in a cool, dry place away from direct sunlight. Do not freeze. Keep the injection in its original packaging until it is time to use it. Follow the storage instructions on the label.
Shelf LifeThe shelf life is usually 24 to 36 months from the date of manufacture, but always check the expiry date printed on the pack. Do not use the medicine after the expiry date.
WHO GuidelineThe World Health Organization recommends injectable artesunate as the first-line treatment for severe malaria. Quinine is an alternative when artesunate is not available, but it is no longer the preferred first choice. This information is for education and does not replace local guidelines.
ICMR GuidelineThe Indian Council of Medical Research guidelines for malaria treatment recommend injectable artesunate as the preferred treatment for severe malaria, with quinine as an alternative in certain situations. Always follow the latest national guidelines and your doctor's advice.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
This medicine must be given only by a trained healthcare professional in a setting with emergency support.
2
Monitor blood sugar closely because quinine can cause low blood sugar, especially in patients who are unwell.
3
Check heart rhythm with an electrocardiogram in patients with heart disease or those on other QT-prolonging medicines.
4
Watch for signs of cinchonism such as ringing in the ears, blurred vision, or severe headache, and stop the medicine if these occur.
5
Adjust the dose in patients with kidney or liver disease and in the elderly.
6
Avoid combining with other medicines that affect heart rhythm or blood clotting without careful monitoring.
7
Switch to oral antimalarial treatment as soon as the patient can take medicines by mouth.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High fever with chills and sweating
This medicine is used for severe malaria, which often causes these symptoms.
Likely Use
✅
Severe body aches and headache
Malaria can cause these symptoms, and this medicine treats the underlying infection.
Likely Use
❌
Common cold
This medicine is not used for colds or viral infections.
Not Primary
❌
Night-time leg cramps
This medicine is not recommended for leg cramps because safer treatments are available.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is given as an intramuscular injection, so it bypasses the stomach and is absorbed directly from the muscle into the bloodstream. Absorption from the injection site can vary depending on blood flow to the muscle and the injection technique.
DistributionAfter absorption, quinine spreads widely into body tissues, including the liver, lungs, kidneys, and spleen. It crosses the placenta and is also found in breast milk. It enters red blood cells, which is important because malaria parasites live there.
Protein BindingQuinine is highly bound to plasma proteins, mainly albumin and alpha-1-acid glycoprotein. The exact percentage can vary between individuals and in different disease states.
MetabolismQuinine is mainly broken down in the liver by cytochrome P450 enzymes, especially CYP3A4. Some other enzymes may also play a role. Liver disease or other medicines that affect these enzymes can change how quickly quinine is cleared from the body.
Half-LifeThe elimination half-life of quinine is usually around 8 to 12 hours in healthy adults, but it can be longer in people with liver or kidney problems and in those with severe malaria.
ExcretionQuinine and its breakdown products are mainly removed from the body through the kidneys in urine. Only a small amount is excreted in faeces. Kidney function can affect how quickly the medicine leaves the body.
BioavailabilityBioavailability is not applicable in the usual sense because this medicine is given by intramuscular injection rather than by mouth. The amount reaching the bloodstream depends on absorption from the muscle, which is usually good but can be reduced in poor blood flow.
Onset of ActionThe medicine begins to act soon after injection, but the full effect on malaria parasites takes time. Clinical improvement in fever and other symptoms usually starts within 24 to 48 hours after starting treatment.
Peak Plasma TimeAfter an intramuscular injection, peak levels in the blood are generally reached within 1 to 3 hours, depending on blood flow at the injection site.
Duration of ActionThe effect of a single dose lasts for several hours, and the medicine is usually given at regular intervals as decided by the doctor. The exact duration depends on the dose and the patient's condition.

How It Works

This medicine works inside the red blood cells where malaria parasites live. Quinine enters the parasite and interferes with the digestion of haemoglobin. The parasite normally breaks down haemoglobin to get nutrients, but quinine blocks this process and causes toxic haem molecules to build up inside the parasite. These toxic substances damage the parasite and kill it. Quinine also affects the parasite's ability to grow and multiply. Because it acts on the blood stage of the parasite, it helps control the infection and reduce symptoms of malaria.

Mechanism Steps

1
Entry into red blood cells: Quinine reaches the red blood cells where malaria parasites are present.
2
Concentration in the parasite: The medicine accumulates inside the parasite more than in surrounding healthy tissue.
3
Blocking haemoglobin digestion: Quinine interferes with the parasite's ability to break down haemoglobin for food.
4
Toxic haem build-up: Undigested haem molecules build up and damage the parasite.
5
Parasite death: The parasite is killed, which helps clear the infection from the blood.

💡 How to Take arm q injection

Strength: Intramuscular injection containing quinine. The exact strength is not specified in the available information. Always check the label and follow the doctor's instructions.

1This medicine is given only by a trained healthcare professional.
2It is injected deep into a large muscle, usually the buttock or thigh.
3The injection site is cleaned before the injection.
4The medicine is not for self-administration at home.
5After the injection, you will be monitored for side effects.
6Follow all instructions given by your doctor or nurse.

Dosage Information

Adult DosageThe dose of this medicine is decided by a qualified clinician based on the severity of malaria, the patient's weight, kidney and liver function, and other medical conditions. It is given as a deep intramuscular injection at intervals set by the doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never self-administer this medicine.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine should only be given to children under the supervision of a specialist.
Elderly DosageElderly patients may need lower doses or longer intervals between doses because kidney and liver function can decline with age. The doctor will adjust the dose based on the patient's health and kidney function.
Renal ImpairmentPatients with kidney disease may need a reduced dose or longer intervals between doses because quinine is removed by the kidneys. Kidney function should be checked before and during treatment, and the dose must be individualized by a qualified clinician.
Hepatic ImpairmentPatients with liver disease may clear quinine more slowly and may need a lower dose. Liver function should be monitored, and the dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum daily dose is determined by the treating doctor based on the patient's condition and response. Do not exceed the prescribed dose. Not established from the available information for a fixed maximum.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Grapefruit and grapefruit juice
Avoid
May affect how the body processes quinine and increase side effects.
Tonic water
Avoid large amounts
Contains small amounts of quinine and could add to the effects of the medicine.
Regular meals
Eat normally if you can
Good nutrition helps recovery from malaria, but this medicine is given by injection and does not depend on food.

⏰ What to Do If You Miss a Dose

📌 You miss an appointment for your injection
→ Contact your doctor or clinic as soon as possible to reschedule.
💡 Do not try to make up for the missed dose on your own.
📌 You are late for a scheduled dose in the hospital
→ Inform the nursing staff immediately.
💡 The medical team will decide the best time for the next dose.

⚠️ Side Effects of arm q injection

✅ Common Side Effects

Injection site pain, redness, or swelling (Common)
Apply a cold pack if advised and inform the nurse or doctor if it worsens.
Nausea and vomiting (Common)
Tell the doctor if vomiting is severe or persistent, as fluids or other medicines may be needed.
Headache and dizziness (Common)
Rest and avoid driving or operating machinery until you feel normal.
Ringing in the ears (Common)
Report this to the doctor, especially if it becomes severe or affects hearing.
Blurred vision (Common)
Inform the doctor if vision changes are persistent or worsening.

🚨 Serious Side Effects

Severe low blood sugar (Uncommon but serious)
Seek immediate medical help if you feel shaky, sweaty, confused, or faint.
Severe allergic reaction (Rare)
Get emergency help right away if you have swelling of the face, lips, or throat, or difficulty breathing.
Heart rhythm problems (Rare)
Tell the doctor immediately if you feel palpitations, chest pain, or fainting.
Breakdown of red blood cells (Rare)
Seek urgent care if you notice dark urine, yellow eyes or skin, or unusual tiredness.
Kidney injury (Rare)
Report a big drop in urine output or swelling to the doctor at once.

⚠️ Rare Side Effects

Blood clotting problems
Seek medical attention for unusual bleeding or bruising.
Liver injury
Report yellowing of skin or eyes, dark urine, or severe stomach pain.
Severe skin reactions
Get emergency care for spreading rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Digoxin Major
Ritonavir Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Cimetidine Moderate
Antacids Minor
Grapefruit juice Minor
Alcohol Moderate

🚨 Major Interactions

  • Warfarin and other blood thinners
  • Medicines that prolong the QT interval on the heart tracing
  • Digoxin
  • Ritonavir and other strong CYP3A4 inhibitors

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, and rifampicin
  • Antacids and sucralfate
  • Cimetidine

🍷 Alcohol Interaction

Alcohol should be avoided while receiving this medicine. Alcohol can worsen dizziness, low blood sugar, and stomach upset, and it can put extra strain on the liver. It may also make it harder to judge how the medicine is affecting you.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to quinine or related medicines.","Blackwater fever, a condition with dark urine and breakdown of red blood cells.","Severe heart rhythm problems, especially those that prolong the QT interval.","Glucose-6-phosphate dehydrogenase deficiency, unless the doctor decides it is absolutely necessary.","Certain eye problems such as optic neuritis.","Myasthenia gravis, a muscle weakness condition."]

⚠️ Warnings & Precautions

["This medicine must be given only by a healthcare professional.","Use with caution in patients with heart disease, kidney disease, or liver disease.","Monitor blood sugar closely because quinine can cause low blood sugar.","Avoid in patients with a history of blood disorders unless clearly needed.","Do not use for night-time leg cramps because safer treatments are available.","Tell your doctor about all other medicines you are taking to avoid interactions.","Avoid alcohol during treatment.","Use with caution in elderly patients who may be more sensitive to side effects."]

🤱 Lactation Safety

Quinine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding when used at normal doses, but the baby should be watched for signs of irritability or low blood sugar. Always consult the doctor before use during breastfeeding.

💊 Overdose Management

Overdose of this medicine is a medical emergency. Symptoms may include severe headache, ringing in the ears, blurred vision, confusion, irregular heartbeat, low blood sugar, and seizures. If an overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include monitoring of heart rhythm, blood sugar, and vital signs, along with medicines to control symptoms. There is no specific antidote, so early hospital care is essential.

⏰ Missed Dose

Because this medicine is given by a healthcare professional, missed doses are managed by the treating team. If you miss an appointment for your injection, contact your doctor or clinic as soon as possible to reschedule. Do not try to make up for a missed dose on your own. The doctor will decide the best way to continue your treatment.

Additional Safety Advice

General Safety

This medicine must be given only by a trained healthcare professional in a setting where emergency equipment and medicines are available. Never attempt to inject this medicine yourself. Tell your doctor about all your other medicines, especially heart medicines, blood thinners, diabetes medicines, and other antimalarials, because this medicine can interact with them. Inform the doctor if you are pregnant, planning pregnancy, or breastfeeding. Blood sugar, heart rhythm, blood counts, and kidney function may need to be checked during treatment. Avoid alcohol while receiving this medicine. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments so that your response to treatment can be monitored properly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially low blood sugar, heart rhythm problems, and dizziness. Kidney and liver function may be reduced with age, so the dose may need to be adjusted. Close monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, talk to your doctor before receiving this medicine. Quinine can be used in pregnancy for severe malaria when needed, but the decision should be made by a doctor who can weigh the risks and benefits for you and your baby.

🏥 Post-Surgery Considerations

If you have recently had surgery, tell your doctor before receiving this medicine. Quinine can affect blood sugar and heart rhythm, which may be important after surgery. Your doctor will decide if any dose adjustment or extra monitoring is needed.

🦷 Dental Procedures

Tell your dentist if you are receiving this medicine, especially if you are taking other medicines or have heart problems. Quinine can interact with some medicines used during dental procedures, so your dentist may need to take extra precautions.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest while recovering from malaria.
🥗
Drink clean water and fluids to stay hydrated.
😴
Eat a balanced diet with fruits and vegetables to help your body recover.
💧
Avoid alcohol during treatment.
🧘
Use mosquito nets and repellents to prevent malaria in the future.
🌞
Take all follow-up appointments seriously.

🏋️ Exercise Considerations

Avoid heavy exercise while you are recovering from severe malaria. Rest is important until your strength returns. Light activity can be started gradually as you feel better, but ask your doctor before starting any strenuous exercise.

🥗 Diet Recommendations

Drink plenty of fluids to prevent dehydration.
Eat light, easily digestible meals if you feel nauseated.
Include fruits and vegetables rich in vitamins.
Avoid alcohol during treatment.
Avoid grapefruit and grapefruit juice.

💼 Impact on Daily Work & Life

This medicine is given in a hospital or clinic, and you may need to stay for monitoring. You should not drive or operate heavy machinery until you know how the medicine affects you. Most people need time off work to recover from severe malaria. Follow your doctor's advice about when to return to normal activities.

🛑 When to Stop This Medicine

Do not stop this medicine on your own. The doctor will decide when to stop based on your response to treatment and your ability to take oral medicines. If you develop serious side effects, the doctor may stop the medicine and switch to another treatment. Always consult your doctor before stopping.

📅 Long-Term Use Effects

Long-term use of this medicine is not common because it is usually given for a short period during severe malaria. However, repeated or prolonged use can increase the risk of heart rhythm problems, blood disorders, and nerve or eye problems. Regular monitoring of blood sugar, heart rhythm, blood counts, and kidney and liver function may be needed if treatment is prolonged. Always follow your doctor's advice about the duration of treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Injectable artesunate

The preferred first-line treatment for severe malaria in many guidelines.

Evidence: Well-established
Oral antimalarial medicines

Used once the patient can take medicines by mouth.

Evidence: Well-established
Supportive care

Includes fluids, blood sugar control, and treatment of complications.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions known for this medicine. However, if you are due for any vaccines, tell your doctor that you are receiving this medicine. Malaria itself can affect your immune system, so vaccination plans may need to be discussed with your doctor.

📦 Storage Guide

✅ DO

Store in a cool, dry place away from direct sunlight.

❌ DON'T

Do not freeze the injection.

✅ DO

Keep in the original packaging until use.

❌ DON'T

Do not transfer to unmarked containers.

✅ DO

Check the expiry date before use.

❌ DON'T

Do not use if the solution is discoloured or contains particles.

✈️ Traveling with This Medicine

If you are travelling and need this medicine, carry it in its original packaging with a copy of your prescription. This medicine is usually given in a hospital or clinic, so plan your travel around your treatment schedule. Store it in a cool, dry place away from direct sunlight during travel. Check the rules of your destination country about carrying prescription medicines, and carry a doctor's letter if needed. Do not pack it in checked luggage if you need it during the journey.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe malaria who could not take oral medicines
He was admitted with high fever, chills, and vomiting. He was given this medicine as an intramuscular injection by the hospital team. His fever started coming down within two days, and he was switched to oral antimalarial tablets when he could eat and drink normally.
💡 Lesson: This medicine is used for severe malaria when oral treatment is not possible, and it works best when given early under medical supervision.
👤 A 50-year-old woman with malaria and low blood sugar
She received this medicine for severe malaria. During treatment, her blood sugar dropped, and she felt sweaty and confused. The medical team checked her blood sugar regularly and treated the low sugar promptly. She recovered well after the dose was adjusted.
💡 Lesson: Blood sugar should be monitored during treatment with this medicine because it can cause low blood sugar.

💬 Questions Patients Often Ask

Q: How is this medicine given?

A: This medicine is given as a deep intramuscular injection by a trained healthcare professional, usually in a hospital or clinic.

Q: How long does it take to work?

A: Fever and other symptoms usually start improving within 24 to 48 hours after starting treatment, but the full course must be completed as advised.

Q: Can I take this medicine if I am pregnant?

A: It may be used in pregnancy for severe malaria under close medical supervision. Your doctor will decide if the benefits outweigh the risks.

Q: What are the serious side effects I should watch for?

A: Watch for severe low blood sugar, allergic reactions, heart rhythm problems, dark urine, yellow eyes or skin, and unusual bleeding. Seek immediate medical help if any of these occur.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long will I need this injection?
  • Will this medicine affect my blood sugar?
  • Can I take this medicine with my heart medicines?
  • Is this medicine safe in pregnancy?
  • What should I do if I miss a dose?

🔄 Substitutes for arm q injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for night-time leg cramps.
    Fact: This medicine is not recommended for leg cramps because safer treatments are available and it can cause serious side effects.
  • Myth: This medicine can be self-injected at home.
    Fact: This medicine must only be given by a trained healthcare professional in a medical setting.
  • Myth: This medicine is the first choice for all types of malaria.
    Fact: It is used mainly for severe malaria when oral treatment is not possible. Other medicines are preferred for uncomplicated malaria.

🔄 Alternative Options

Generic Alternatives

  • Quinine injection

Brand Alternatives

  • Arm Q Injection

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Cinchona alkaloid antimalarial","route":"Intramuscular","main_use":"Severe malaria","note":"Alternative when artesunate is not available."},{"medicine":"Artesunate injection","class":"Artemisinin antimalarial","route":"Intravenous or intramuscular","main_use":"Severe malaria","note":"Preferred first-line treatment for severe malaria."},{"medicine":"Artemether injection","class":"Artemisinin antimalarial","route":"Intramuscular","main_use":"Severe malaria","note":"Used when artesunate is not available."}]

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