ariof oz 200mg/500mg tablet - Ofloxacin (200mg) + Ornidazole (500mg) medicine

Ariof OZ 200mg/500mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Ariane Biotech ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is ariof oz 200mg/500mg tablet used for?

Ariof OZ 200mg/500mg Tablet is a combination antibiotic used to treat diarrhea and dysentery caused by bacterial or parasitic infections. It contains Ofloxacin, which kills bacteria, and Ornidazole, which kills parasites, working together to stop the infection and relieve symptoms like loose stools and abdominal pain.

  • Generic Name: Ofloxacin + Ornidazole
  • Manufacturer: Ariane Biotech
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š ariof oz 200mg/500mg tablet Uses & Benefits

Gastrointestinal infections, diarrhea, dysentery, intra-abdominal infections

Off-label uses: Pelvic inflammatory disease, prostatitis

๐Ÿ“‹ Drug Information

Generic Name(s)Ofloxacin + Ornidazole
Brand NameAssault Novo 200 mg/500 mg Tablet
ManufacturerAriane Biotech
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntibiotic + Antiprotozoal
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract
DistributionDistributes widely into body tissues and fluids
Protein BindingOfloxacin: 20-25%; Ornidazole: <15%
MetabolismOfloxacin: Hepatic (minimal); Ornidazole: Hepatic via CYP450
Half-LifeOfloxacin: 4-5 hours; Ornidazole: 12-14 hours
ExcretionOfloxacin: Renal (80-90% unchanged); Ornidazole: Renal (60-70% as metabolites)
BioavailabilityOfloxacin: 98%; Ornidazole: 90%
Onset of ActionWithin 1-2 hours
Peak Plasma TimeOfloxacin: 1-2 hours; Ornidazole: 2-4 hours
Duration of ActionUp to 24 hours

How It Works

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; Ornidazole disrupts DNA structure in anaerobic organisms

Mechanism Steps

1Ofloxacin enters bacterial cell and inhibits DNA gyrase and topoisomerase IV
2Inhibition prevents DNA supercoiling and replication
3Ornidazole enters anaerobic organisms and is reduced by bacterial nitroreductases

๐Ÿ’ก How to Take ariof oz 200mg/500mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ariof oz 200mg/500mg tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Metallic taste

๐Ÿšจ Serious Side Effects

  • Tendon rupture
  • Peripheral neuropathy
  • QT prolongation
  • Seizures
  • Clostridium difficile colitis

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Insulin Moderate Hypoglycemia risk
NSAIDs Moderate Increased CNS side effects

๐Ÿšจ Major Interactions

  • Warfarin
  • Antidiabetic agents
  • QT-prolonging drugs

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antacids containing magnesium or aluminum

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

Avoid dairy products, antacids, and iron supplements within 2 hours of dosing

๐Ÿท Alcohol Interaction

Avoid alcohol; may cause disulfiram-like reaction with Ornidazole

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to fluoroquinolones or nitroimidazoles, epilepsy, history of tendon disorders with quinolones, pregnancy, lactation

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood glucose, ECG for QT prolongation

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote; hemodialysis may help

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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