Ariba L 75mg/20mg Capsule - Uses, Price, Side Effects
What is ariba l 75mg/20mg capsule used for?
Ariba L 75mg/20mg Capsule is a combination of Levosulpiride (75mg) and Rabeprazole (20mg) used to treat gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and functional dyspepsia. Levosulpiride improves gastric motility and emptying, while Rabeprazole reduces stomach acid production, providing relief from heartburn, bloating, and discomfort.
- Generic Name: Levosulpiride + Rabeprazole
- Manufacturer: Grapple Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ ariba l 75mg/20mg capsule Uses & Benefits
Gastroesophageal reflux disease (GERD); dyspepsia; gastroparesis; irritable bowel syndrome with constipation
Off-label uses: Diabetic gastroparesis; functional dyspepsia; cyclic vomiting syndrome
๐ Drug Information
| Generic Name(s) | Levosulpiride + Rabeprazole |
| Brand Name | Acera-L Capsule SR |
| Manufacturer | Grapple Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral (sustained release capsule) |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levosulpiride: Dopamine D2 receptor antagonist in GI tract, enhancing motility; Rabeprazole: Irreversible inhibition of H+/K+ ATPase in gastric parietal cells, reducing acid secretion
Mechanism Steps
๐ก How to Take ariba l 75mg/20mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of ariba l 75mg/20mg capsule
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Dizziness
- Constipation
๐จ Serious Side Effects
- QT prolongation
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- Clostridium difficile infection
- Fractures (long-term)
โ ๏ธ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Interstitial nephritis
- Lupus erythematosus
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Ketoconazole | Moderate | Increased rabeprazole levels |
| Methotrexate | Major | Increased methotrexate toxicity |
๐จ Major Interactions
- Warfarin
- Clopidogrel
- Methotrexate
- Cilostazol
- Atazanavir
โก Moderate Interactions
- Diazepam
- Phenytoin
- Digoxin
- Ketoconazole
- Iron salts
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Vitamin B12
๐ฝ๏ธ Food Interactions
Food may delay absorption of both components; avoid high-fat meals
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of GI side effects
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components; GI hemorrhage; mechanical obstruction; perforation; pheochromocytoma; concomitant use with neuroleptics
๐ Monitoring Parameters
Liver function tests; renal function; ECG (QT interval); serum electrolytes; magnesium levels
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Supportive care; activated charcoal; monitor ECG for QT prolongation
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.