apxaban 2.5 tablet - Uses, Price, Side Effects & Substitutes
What is apxaban 2.5 tablet used for?
Apigat 2.5 Tablet (Apixaban) is used to treat BLOOD RELATED. It contains Apixaban (2.5mg), which Direct, selective, reversible inhibition of free and clot-bound factor Xa, there. Always consult your doctor before use. Take as prescribed.
- Generic Name: Apixaban
- Manufacturer: Care Formulation Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ apxaban 2.5 tablet Uses & Benefits
Prevention of stroke and systemic embolism in nonvalvular atrial fibrillation; treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE); prophylaxis of DVT following hip or knee replacement surgery.
Off-label uses: Anticoagulation in patients with heparin-induced thrombocytopenia (HIT); thromboprophylaxis in cancer patients; use in pediatric patients (limited data).
๐ Drug Information
| Generic Name(s) | Apixaban |
| Brand Name | Apigat 2.5 Tablet |
| Manufacturer | Care Formulation Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Oral Factor Xa Inhibitors |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); excursions permitted to 15-30ยฐC (59-86ยฐF). Protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Direct, selective, reversible inhibition of free and clot-bound factor Xa, thereby reducing thrombin generation and thrombus formation.
Mechanism Steps
๐ก How to Take apxaban 2.5 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of apxaban 2.5 tablet
โ Common Side Effects
- Bleeding (e.g., epistaxis, contusion, hematuria, gingival bleeding)
- Anemia
- Nausea
๐จ Serious Side Effects
- Major bleeding (intracranial, gastrointestinal, retroperitoneal)
- Spinal/epidural hematoma with neuraxial anesthesia
- Thrombocytopenia
โ ๏ธ Rare Side Effects
- Hypersensitivity reactions (rash, urticaria, anaphylaxis)
- Hepatotoxicity
- Jaundice
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Rifampin | Major | Decreased apixaban exposure and efficacy |
| Ketoconazole | Major | Increased apixaban exposure and bleeding risk |
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| Amiodarone | Moderate | Increased apixaban exposure |
| Diltiazem | Moderate | Increased apixaban exposure |
| Digoxin | Minor | No significant interaction |
๐จ Major Interactions
- Rifampin
- Phenytoin
- Carbamazepine
- Phenobarbital
- St. John's Wort
- Ketoconazole
- Itraconazole
- Ritonavir
- Clarithromycin
- Warfarin
- Heparin
- Enoxaparin
- Aspirin
- Clopidogrel
- Prasugrel
- Ticagrelor
- NSAIDs
- SSRIs
- SNRIs
โก Moderate Interactions
- Amiodarone
- Diltiazem
- Verapamil
- Quinidine
- Dronedarone
- Fluconazole
- Cyclosporine
- Tacrolimus
- Lopinavir
- Atazanavir
- Indinavir
- Nelfinavir
- Saquinavir
- Boceprevir
- Telaprevir
- Cobicistat
โน๏ธ Minor Interactions
- Digoxin
- Atorvastatin
- Omeprazole
- Famotidine
- Aluminum hydroxide
- Naproxen
๐ฝ๏ธ Food Interactions
No significant food interactions; can be taken with or without food.
๐ท Alcohol Interaction
Alcohol may increase bleeding risk; avoid excessive alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active pathological bleeding; severe hypersensitivity to apixaban; severe hepatic impairment (Child-Pugh C); concomitant treatment with strong CYP3A4 and P-gp inducers; mechanical prosthetic heart valves; antiphospholipid syndrome (triple positive).
๐ Monitoring Parameters
Assess renal function (CrCl) before and during therapy; monitor for signs of bleeding; no routine coagulation monitoring required.
๐คฑ Lactation Safety
Not recommended; apixaban is excreted in rat milk, unknown in human milk; discontinue drug or nursin
๐ Overdose Management
Activated charcoal may reduce absorption; no specific antidote; consider prothrombin complex concentrate (PCC) or recombinant factor VIIa; hemodialysis not effective.
โฐ Missed Dose
If missed dose, take as soon as remembered on same day; do not double dose next day; resume regular schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for apxaban 2.5 tablet
View AllAlternative brands with exact same active ingredient (Apixaban (2.5mg)):
-
Apixabid 2.5 TabletIndoco Remedies Ltd โน102.00 68.8% CHEAPER
-
prepixa 2.5 tabletEmcure Pharmaceuticals Ltd โน120.00 63.3% CHEAPER
-
pixaflo 2.5mg tabletLupin Ltd โน127.50 61% CHEAPER
-
apixator 2.5 tabletTorrent Pharmaceuticals Ltd โน149.39 54.3% CHEAPER
-
paxiba 2.5 tabletGlenmark Pharmaceuticals Ltd โน150.00 54.2% CHEAPER
-
zuvixa 2.5mg tabletZuventus Healthcare Ltd โน164.85 49.6% CHEAPER
-
apivas 2.5 tabletMicro Labs Ltd โน167.80 48.7% CHEAPER
-
apigy 2.5 tabletCipla Ltd โน170.10 48% CHEAPER
-
xapilis 2.5 tabletAbbott โน210.00 35.8% CHEAPER
-
eliquis 2.5mg tabletPfizer Ltd โน435.00 33% COSTLIER
Medical Note: Always consult your doctor before switching medications.