apixator 2.5 tablet

4.5 (17 reviews)

Apixaban (2.5mg)

🏭 Torrent Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is apixator 2.5 tablet used for?

Apigat 2.5 Tablet (Apixaban) is used to treat BLOOD RELATED. It contains Apixaban (2.5mg), which Direct, selective, reversible inhibition of free and clot-bound factor Xa, there. Always consult your doctor before use. Take as prescribed.

Generic Name: Apixaban
Manufacturer: Torrent Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 apixator 2.5 tablet Uses & Benefits

Prevention of stroke and systemic embolism in nonvalvular atrial fibrillation; treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE); prophylaxis of DVT following hip or knee replacement surgery.

Off-label uses: Anticoagulation in patients with heparin-induced thrombocytopenia (HIT); thromboprophylaxis in cancer patients; use in pediatric patients (limited data).

📋 Drug Information

Generic Name(s)	Apixaban
Brand Name	Apigat 2.5 Tablet
Manufacturer	Torrent Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	BLOOD RELATED
Action Class	Oral Factor Xa Inhibitors
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); excursions permitted to 15-30°C (59-86°F). Protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; absolute bioavailability is approximately 50% for doses up to 10 mg.

DistributionVolume of distribution is about 21 L; plasma protein binding is approximately 87%.

Protein Binding87%

MetabolismMetabolized primarily via CYP3A4/5, with minor contributions from CYP1A2, CYP2C8, CYP2C9, CYP2C19, and CYP2J2; also undergoes O-demethylation and hydroxylation.

Half-LifeApproximately 12 hours (range 8-15 hours) in healthy subjects; prolonged in renal impairment.

Excretion25% excreted unchanged in urine; 55% as metabolites in feces; 27% in urine as metabolites.

BioavailabilityApproximately 50%

Onset of ActionRapid; peak effect within 3-4 hours.

Peak Plasma Time3-4 hours

Duration of Action12 hours (twice-daily dosing maintains therapeutic levels)

How It Works

Direct, selective, reversible inhibition of free and clot-bound factor Xa, thereby reducing thrombin generation and thrombus formation.

Mechanism Steps

1Apixaban binds directly to the active site of factor Xa (both free and clot-bound).

2Inhibition of factor Xa prevents conversion of prothrombin to thrombin.

3Reduced thrombin levels decrease fibrin formation and platelet activation.

💡 How to Take apixator 2.5 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of apixator 2.5 tablet

✅ Common Side Effects

Bleeding (e.g., epistaxis, contusion, hematuria, gingival bleeding)
Anemia
Nausea

🚨 Serious Side Effects

Major bleeding (intracranial, gastrointestinal, retroperitoneal)
Spinal/epidural hematoma with neuraxial anesthesia
Thrombocytopenia

⚠️ Rare Side Effects

Hypersensitivity reactions (rash, urticaria, anaphylaxis)
Hepatotoxicity
Jaundice

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Rifampin	Major	Decreased apixaban exposure and efficacy
Ketoconazole	Major	Increased apixaban exposure and bleeding risk
Warfarin	Major	Increased bleeding risk
Aspirin	Major	Increased bleeding risk
Clopidogrel	Major	Increased bleeding risk
Amiodarone	Moderate	Increased apixaban exposure
Diltiazem	Moderate	Increased apixaban exposure
Digoxin	Minor	No significant interaction

🚨 Major Interactions

Rifampin
Phenytoin
Carbamazepine
Phenobarbital
St. John's Wort
Ketoconazole
Itraconazole
Ritonavir
Clarithromycin
Warfarin
Heparin
Enoxaparin
Aspirin
Clopidogrel
Prasugrel
Ticagrelor
NSAIDs
SSRIs
SNRIs

⚡ Moderate Interactions

Amiodarone
Diltiazem
Verapamil
Quinidine
Dronedarone
Fluconazole
Cyclosporine
Tacrolimus
Lopinavir
Atazanavir
Indinavir
Nelfinavir
Saquinavir
Boceprevir
Telaprevir
Cobicistat

ℹ️ Minor Interactions

Digoxin
Atorvastatin
Omeprazole
Famotidine
Aluminum hydroxide
Naproxen

🍽️ Food Interactions

No significant food interactions; can be taken with or without food.

🍷 Alcohol Interaction

Alcohol may increase bleeding risk; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Active pathological bleeding; severe hypersensitivity to apixaban; severe hepatic impairment (Child-Pugh C); concomitant treatment with strong CYP3A4 and P-gp inducers; mechanical prosthetic heart valves; antiphospholipid syndrome (triple positive).

📊 Monitoring Parameters

Assess renal function (CrCl) before and during therapy; monitor for signs of bleeding; no routine coagulation monitoring required.

🤱 Lactation Safety

Not recommended; apixaban is excreted in rat milk, unknown in human milk; discontinue drug or nursin

💊 Overdose Management

Activated charcoal may reduce absorption; no specific antidote; consider prothrombin complex concentrate (PCC) or recombinant factor VIIa; hemodialysis not effective.

⏰ Missed Dose

If missed dose, take as soon as remembered on same day; do not double dose next day; resume regular schedule.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for apixator 2.5 tablet

View All

Alternative brands with exact same active ingredient (Apixaban (2.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.