apretero 125/80 kit
What is apretero 125/80 kit used for?
Aprecap 125/80 Capsule (Aprepitant) is used to treat GASTRO INTESTINAL. It contains Aprepitant (125mg) + Aprepitant (80mg), which Selective antagonist at substance P/neurokinin 1 (NK1) receptors in the brain, i. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aprepitant
- Manufacturer: Hetero Drugs Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ apretero 125/80 kit Uses & Benefits
๐ Drug Information
| Generic Name(s) | Aprepitant |
| Brand Name | Aprecap 125/80 Capsule |
| Manufacturer | Hetero Drugs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Substance P/Neurokinin 1 (NK1) Receptor Antagonist |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective antagonist at substance P/neurokinin 1 (NK1) receptors in the brain, inhibiting emetic signals
Mechanism Steps
๐ก How to Take apretero 125/80 kit
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of apretero 125/80 kit
โ Common Side Effects
- Fatigue
- Nausea
- Diarrhea
- Headache
- Hiccups
- Dizziness
๐จ Serious Side Effects
- Stevens-Johnson syndrome
- Angioedema
- Anaphylaxis
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- QT prolongation
- Seizures
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Decreased anticoagulant effect |
| Oral contraceptives | Major | Reduced contraceptive efficacy |
| Cisapride | Major | Increased risk of arrhythmias |
| Pimozide | Major | Increased risk of QT prolongation |
| Ergot alkaloids | Major | Increased ergot toxicity |
| Lovastatin | Major | Increased statin levels |
| Simvastatin | Major | Increased statin levels |
| Midazolam | Major | Increased sedation |
| Triazolam | Major | Increased sedation |
| Diltiazem | Moderate | Increased aprepitant levels |
| Ketoconazole | Moderate | Increased aprepitant levels |
| Itraconazole | Moderate | Increased aprepitant levels |
| Clarithromycin | Moderate | Increased aprepitant levels |
| Ritonavir | Moderate | Increased aprepitant levels |
| Nelfinavir | Moderate | Increased aprepitant levels |
| Rifampin | Moderate | Decreased aprepitant levels |
| Carbamazepine | Moderate | Decreased aprepitant levels |
| Phenytoin | Moderate | Decreased aprepitant levels |
| Cimetidine | Minor | Minimal interaction |
| Omeprazole | Minor | Minimal interaction |
| Paroxetine | Minor | Minimal interaction |
| Sertraline | Minor | Minimal interaction |
๐จ Major Interactions
- Warfarin
- Oral contraceptives
- Cisapride
- Pimozide
- Ergot alkaloids
- Lovastatin
- Simvastatin
- Midazolam
- Triazolam
โก Moderate Interactions
- Diltiazem
- Ketoconazole
- Itraconazole
- Clarithromycin
- Ritonavir
- Nelfinavir
- Rifampin
- Carbamazepine
- Phenytoin
โน๏ธ Minor Interactions
- Cimetidine
- Omeprazole
- Paroxetine
- Sertraline
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase levels; high-fat meal may decrease absorption
๐ท Alcohol Interaction
No significant interaction reported
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to aprepitant or any component
๐ Monitoring Parameters
Liver function tests; signs of hypersensitivity
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Supportive care; no specific antidote
โฐ Missed Dose
If missed within 1 hour, take as soon as remembered; otherwise skip and resume next dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.