Aprazol 0.5mg Tablet - Uses, Price, Side Effects
What is aprazol 0.5mg tablet used for?
Aprazol 0.5mg Tablet contains Lansoprazole, a proton pump inhibitor that reduces stomach acid production. It is used to treat gastroesophageal reflux disease (GERD), gastric ulcers, and other acid-related conditions. It works by blocking the enzyme in the stomach wall that produces acid, providing relief from heartburn and promoting healing of the esophagus.
- Generic Name: Lansoprazole
- Manufacturer: Drakt Pharmaceutical Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aprazol 0.5mg tablet Uses & Benefits
- Gastroesophageal reflux disease (GERD), peptic ulcer disease, Zollinger-Ellison syndrome, erosive esophagitis, H.
- pylori eradication (combination therapy).
Off-label uses: Stress ulcer prophylaxis, dyspepsia, Barrett's esophagus.
๐ Drug Information
| Generic Name(s) | Lansoprazole |
| Brand Name | Aprazol 0.5mg Tablet |
| Manufacturer | Drakt Pharmaceutical Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton pump inhibitors |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme (proton pump) in gastric parietal cells.
Mechanism Steps
๐ก How to Take aprazol 0.5mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of aprazol 0.5mg tablet
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Constipation
- Flatulence
๐จ Serious Side Effects
- Clostridium difficile-associated diarrhea
- Fractures (hip, wrist, spine)
- Hypomagnesemia
- Vitamin B12 deficiency
- Cutaneous lupus erythematosus
โ ๏ธ Rare Side Effects
- Interstitial nephritis
- Hepatotoxicity
- Pancreatitis
- Stevens-Johnson syndrome
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Clopidogrel | Major | Reduced antiplatelet effect |
| Methotrexate | Major | Increased methotrexate toxicity |
| Cilostazol | Major | Increased cilostazol levels |
| Diazepam | Moderate | Increased diazepam levels |
| Phenytoin | Moderate | Increased phenytoin levels |
| Theophylline | Moderate | Increased theophylline levels |
| Tacrolimus | Moderate | Increased tacrolimus levels |
| Sucralfate | Minor | Reduced absorption of lansoprazole |
| Antacids | Minor | Reduced absorption of lansoprazole |
| Digoxin | Minor | Possible increased digoxin levels |
๐จ Major Interactions
- Warfarin
- Clopidogrel
- Methotrexate
- Cilostazol
โก Moderate Interactions
- Diazepam
- Phenytoin
- Theophylline
- Tacrolimus
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Digoxin
๐ฝ๏ธ Food Interactions
Food may delay absorption; best taken before meals.
๐ท Alcohol Interaction
No significant interaction; alcohol may worsen gastric irritation.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to lansoprazole or any component; concomitant use with rilpivirine.
๐ Monitoring Parameters
Symptoms of GI conditions; liver function tests; magnesium levels (long-term use).
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Supportive care; no specific antidote; hemodialysis not effective.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose.