appben syrup
What is appben syrup used for?
ABD Plus Tablet (Ivermectin + Albendazole) is used to treat ANTI INFECTIVES. It contains Ivermectin (6mg) + Albendazole (400mg), which Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ivermectin + Albendazole
- Manufacturer: Santiago Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ appben syrup Uses & Benefits
Filariasis, strongyloidiasis, ascariasis, hookworm, trichuriasis, enterobiasis
Off-label uses: Scabies, lice, cutaneous larva migrans
๐ Drug Information
| Generic Name(s) | Ivermectin + Albendazole |
| Brand Name | ABD Plus Tablet |
| Manufacturer | Santiago Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells, causing hyperpolarization and paralysis; Albendazole: inhibits tubulin polymerization, disrupting microtubule formation and glucose uptake
Mechanism Steps
๐ก How to Take appben syrup
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of appben syrup
โ Common Side Effects
- Nausea
- vomiting
- diarrhea
- abdominal pain
- headache
- dizziness
๐จ Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- agranulocytosis
- seizures
โ ๏ธ Rare Side Effects
- Alopecia
- acute renal failure
- pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Theophylline | Major | Increased theophylline toxicity |
| Ketoconazole | Major | Increased ivermectin/albendazole levels |
| Rifampin | Moderate | Decreased albendazole levels |
| Grapefruit juice | Minor | Altered metabolism |
๐จ Major Interactions
- Warfarin
- Theophylline
- CYP3A4 inhibitors (e.g., ketoconazole)
โก Moderate Interactions
- CYP3A4 inducers (e.g., rifampin)
- P-glycoprotein inhibitors
โน๏ธ Minor Interactions
- Grapefruit juice
๐ฝ๏ธ Food Interactions
Fatty meal increases absorption of albendazole; avoid grapefruit juice
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, pregnancy, lactation, hepatic impairment
๐ Monitoring Parameters
Liver function tests, renal function, blood counts
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage if recent
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.