Bandy-Plus Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face or throat, difficulty breathing.
- Neurological symptoms: confusion, seizures, loss of coordination.
- Signs of liver problems: yellowing of skin or eyes, dark urine, severe abdominal pain.
- Signs of bone marrow suppression: unusual bruising or bleeding, frequent infections.
- Persistent vomiting or diarrhoea leading to dehydration.
- Blood in stool or vomit.
If experiencing severe symptoms, call emergency services immediately.
What is appben 6mg/400mg tablet used for?
This medicine is a combination of Ivermectin and Albendazole used to treat intestinal worm infections. It works by paralysing and killing the worms, which are then expelled from the body. It is usually taken as a single dose with food.
- Generic Name: Ivermectin (6mg) + Albendazole (400mg)
- Manufacturer: Santiago Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 appben 6mg/400mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इवरमेक्टिन और अल्बेंडाजोल का संयोजन है, जिसका उपयोग आंतों के कीड़ों के संक्रमण के इलाज के लिए किया जाता है। यह कीड़ों को लकवा मारकर और मारकर शरीर से बाहर निकालने में मदद करती है। यह आमतौर पर खाने के साथ एक खुराक के रूप में ली जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दौरे, या यकृत की समस्या हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। शराब का सेवन न करें। यकृत या गुर्दे की बीमारी हो तो डॉक्टर को बताएं। चक्कर आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 appben 6mg/400mg tablet Uses & Benefits
[{"condition":"Intestinal worm infections (e.g., ascariasis, hookworm, strongyloidiasis)","description":"This medicine is used to treat a variety of intestinal nematode infections by paralysing and killing the worms, which are then passed in the stool.","evidence":"Well-established"},{"condition":"Scabies","description":"Ivermectin in this combination is effective against scabies mites, and albendazole may provide additional antiparasitic coverage.","evidence":"Moderate"},{"condition":"Lymphatic filariasis","description":"Used in mass drug administration programmes to reduce transmission, though the combination may be used in specific cases.","evidence":"Established for ivermectin alone; combination evidence limited"}]
Off-label uses: [{"condition":"Rosacea","description":"Ivermectin has been used off-label for rosacea due to its anti-inflammatory and anti-parasitic effects, but the combination with albendazole is not standard.","evidence":"Limited"},{"condition":"Head lice","description":"Ivermectin may be used off-label for head lice, but albendazole is not typically included.","evidence":"Limited"}]
Primary treatment for: Intestinal worm infections
Also treats: Scabies, Lymphatic filariasis
📋 Drug Information
| Generic Name(s) | Ivermectin (6mg) + Albendazole (400mg) |
| Brand Name | appben 6mg/400mg tablet |
| Manufacturer | Santiago Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Ivermectin and albendazole are included in the WHO Model List of Essential Medicines for the treatment of soil-transmitted helminthiases and other parasitic infections. However, the fixed-dose combination is not specifically recommended by WHO for all indications. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two anthelmintics with complementary mechanisms. Ivermectin binds to glutamate-gated chloride channels in the nerve and muscle cells of parasites, causing hyperpolarisation and paralysis. Albendazole binds to tubulin, inhibiting microtubule polymerisation, which disrupts glucose uptake and energy metabolism in the parasites, leading to their death. Together, they provide a broad spectrum of activity against various nematodes and some ectoparasites.
Mechanism Steps
💡 How to Take appben 6mg/400mg tablet
Strength: Tablet containing Ivermectin 6 mg and Albendazole 400 mg.
Dosage Information
| Adult Dosage | The usual adult dose for intestinal worm infections is one tablet (Ivermectin 6 mg + Albendazole 400 mg) orally as a single dose, or as directed by the physician. For some infections, repeated doses may be required. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced liver or kidney function; dose adjustment may be necessary. Consult your doctor. |
| Renal Impairment | No specific dose adjustment guidelines are available. Use with caution in patients with renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be required. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended dose is one tablet per day, but this may vary based on the indication. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of appben 6mg/400mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| CNS depressants | Major | |
| CYP3A4 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- CNS depressants (e.g., benzodiazepines, opioids)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and CNS side effects such as dizziness and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ivermectin or albendazole.","Pregnancy, especially during the first trimester.","Children under 15 kg (or as specified by the manufacturer).","Concurrent use with live vaccines.","Severe liver disease."]
⚠️ Warnings & Precautions
["Use with caution in patients with liver or kidney impairment.","Avoid in patients with a history of seizures.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use in patients with onchocerciasis who also have loiasis, as it may cause severe adverse reactions.","Not recommended for children under 15 kg.","Avoid alcohol during treatment."]
🤱 Lactation Safety
Ivermectin is excreted in breast milk in low amounts. Albendazole and its metabolites are also excreted in breast milk. The safety in nursing infants is not well established. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhoea, dizziness, and in severe cases, neurological symptoms. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not self-medicate or share it with others. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. If you have liver or kidney disease, your doctor may need to adjust the dose or monitor you more closely. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced liver or kidney function, requiring dose adjustment and closer monitoring. They may also be more susceptible to side effects such as dizziness and confusion.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the first trimester. If you are planning pregnancy, consult your doctor for alternative treatments and preconception counselling.
🏥 Post-Surgery Considerations
There are no specific restrictions, but inform your surgeon if you are taking this medicine before surgery. It may interact with anaesthetics or other medications.
🦷 Dental Procedures
No specific precautions are needed for dental procedures, but inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue after taking this medicine, avoid strenuous exercise until you feel normal.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually taken as a single dose, so impact on work life is minimal.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not typically recommended unless under medical supervision for specific conditions. Prolonged use may lead to liver enzyme elevations, bone marrow suppression, and neurological effects. Regular monitoring of liver function and blood counts may be advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another anthelmintic that may be used for similar infections.
Evidence: Well-establishedUsed for certain intestinal worms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with albendazole-containing products due to potential reduced immune response. Consult your doctor regarding vaccination schedules.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it as prescribed; for single-dose regimens, timing is not critical. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The medicine starts working within hours, but it may take a few days to see improvement in symptoms as the worms are expelled.
A: Yes, taking it with food improves absorption and reduces stomach upset.
A: It is not recommended for children under 15 kg. Consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any stomach problem.
Fact: It is specifically for parasitic worm infections and should not be used for general stomach issues. - Myth: It is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Ivermectin 6 mg + Albendazole 400 mg tablets from other manufacturers
Brand Alternatives
- Bandy-Plus Tablet