apkocid 40mg tablet - Pantoprazole (40mg) medicine

Apkocid 40mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Akpash Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is apkocid 40mg tablet used for?

Apkocid 40mg Tablet contains Pantoprazole, a proton pump inhibitor that reduces stomach acid production. It is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It helps relieve heartburn, acid regurgitation, and stomach pain.

  • Generic Name: Pantoprazole
  • Manufacturer: Akpash Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š apkocid 40mg tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (combination therapy), peptic ulcer disease.

Off-label uses: Stress ulcer prophylaxis in critically ill patients; prevention of NSAID-induced ulcers.

๐Ÿ“‹ Drug Information

Generic Name(s)Pantoprazole
Brand NameAciban 40 Tablet
ManufacturerAkpash Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; absorption is rapid and complete.
DistributionVolume of distribution about 0.15 L/kg; extensively distributed in tissues.
Protein BindingApproximately 98% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes.
Half-LifeAbout 1 hour (range 0.5-1.5 hours) in healthy subjects; prolonged in hepatic impairment.
ExcretionPrimarily renal (about 80% as metabolites); remainder in feces.
BioavailabilityOral bioavailability about 77%.
Onset of ActionWithin 1 hour; maximal acid suppression occurs after 2-4 days of dosing.
Peak Plasma Time2-3 hours after oral administration.
Duration of ActionAcid suppression lasts up to 24 hours after a single dose.

How It Works

Proton pump inhibitor that irreversibly inhibits H+/K+ ATPase in gastric parietal cells.

Mechanism Steps

1Pantoprazole is a prodrug that accumulates in the acidic environment of gastric parietal cell canaliculi.
2It is protonated and converted to its active form, a sulfenamide.
3The active form binds covalently to cysteine residues of the H+/K+ ATPase enzyme.

๐Ÿ’ก How to Take apkocid 40mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โŒ ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of apkocid 40mg tablet

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Constipation

๐Ÿšจ Serious Side Effects

  • Clostridium difficile-associated diarrhea
  • Fractures (hip, wrist, spine) with long-term use
  • Hypomagnesemia
  • Vitamin B12 deficiency
  • Acute interstitial nephritis
  • Cutaneous lupus erythematosus

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Pancreatitis
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate May increase INR and bleeding risk
Methotrexate Major May increase methotrexate toxicity
Ketoconazole Moderate May decrease absorption of ketoconazole

๐Ÿšจ Major Interactions

  • Clopidogrel
  • Methotrexate
  • Atazanavir
  • Rilpivirine
  • Cilostazol

โšก Moderate Interactions

  • Warfarin
  • Phenytoin
  • Diazepam
  • Digoxin
  • Iron salts
  • Mycophenolate mofetil

โ„น๏ธ Minor Interactions

  • Ketoconazole
  • Itraconazole
  • Ampicillin esters
  • Sucralfate

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not affect extent; best taken before meals.

๐Ÿท Alcohol Interaction

No direct interaction; alcohol may aggravate gastric conditions.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category B

๐Ÿšซ Contraindications

Hypersensitivity to pantoprazole or any component; co-administration with rilpivirine.

๐Ÿ“Š Monitoring Parameters

Symptoms of acid-related disorders; magnesium levels with prolonged use; bone density with long-term use.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote; hemodialysis not effective.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for apkocid 40mg tablet

View All

Alternative brands with exact same active ingredient (Pantoprazole (40mg)):

Medical Note: Always consult your doctor before switching medications.

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