apitase syrup - Cyproheptadine (2mg) + Tricholine Citrate (275mg) medicine

Apitase Syrup - Uses, Price, Side Effects

4.8 (14 reviews)
๐Ÿญ Allentis Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is apitase syrup used for?

Apitase Syrup is a combination of Cyproheptadine (2mg) and Tricholine Citrate (275mg). Cyproheptadine is an antihistamine that stimulates appetite, while Tricholine Citrate supports liver function. It is used to increase appetite and improve digestion.

  • Generic Name: Cyproheptadine + Tricholine Citrate
  • Manufacturer: Allentis Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š apitase syrup Uses & Benefits

Appetite stimulation, weight gain, allergic conditions, liver support

Off-label uses: Migraine prophylaxis, pruritus, serotonin syndrome adjunct

๐Ÿ“‹ Drug Information

Generic Name(s)Cyproheptadine + Tricholine Citrate
Brand NameAptimust Syrup
ManufacturerAllentis Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassAppetite Stimulant, Antihistamine, Hepatoprotective
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract
DistributionDistributed throughout body, crosses blood-brain barrier
Protein BindingCyproheptadine: 96-99%
MetabolismCyproheptadine: Hepatic via CYP450; Tricholine Citrate: Metabolized to choline and citrate
Half-LifeCyproheptadine: 16 hours; Tricholine Citrate: Not well defined
ExcretionCyproheptadine: Renal (bile and feces); Tricholine Citrate: Renal
BioavailabilityCyproheptadine: ~50%
Onset of Action1-2 hours
Peak Plasma TimeCyproheptadine: 6-9 hours
Duration of Action8-12 hours

How It Works

Cyproheptadine blocks histamine H1 receptors and serotonin 5-HT2 receptors, stimulating appetite; Tricholine Citrate provides choline for liver function and acts as a lipotropic agent.

Mechanism Steps

1Cyproheptadine competitively blocks histamine H1 receptors in the hypothalamus, reducing histamine-mediated appetite suppression.
2Cyproheptadine blocks serotonin 5-HT2 receptors, which are involved in satiety signaling, thereby increasing appetite.
3Tricholine Citrate dissociates into choline and citrate; choline is used for synthesis of acetylcholine and phospholipids, supporting liver function.

๐Ÿ’ก How to Take apitase syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of apitase syrup

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Increased appetite
  • Weight gain

๐Ÿšจ Serious Side Effects

  • Seizures
  • Hallucinations
  • Urinary retention
  • Blurred vision
  • Tachycardia

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Hemolytic anemia
  • Thrombocytopenia
  • Cholestatic jaundice

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of serotonin syndrome
Alcohol Moderate Increased sedation
Anticholinergics Moderate Additive anticholinergic effects

๐Ÿšจ Major Interactions

  • MAOIs
  • CNS depressants
  • Anticholinergics

โšก Moderate Interactions

  • Antihypertensives
  • SSRIs
  • Alcohol

โ„น๏ธ Minor Interactions

  • Antacids
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase cyproheptadine levels

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, narrow-angle glaucoma, urinary retention, severe hypertension, concurrent MAOI use

๐Ÿ“Š Monitoring Parameters

Appetite, weight, liver function tests, sedation level

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid or use with caution

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; for anticholinergic symptoms, physostigmine may be used

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

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