Dompan Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat, palpitations, or fainting
- Severe allergic reaction with swelling of face, lips, or throat
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent vomiting
- Signs of low magnesium such as muscle cramps, tremors, or seizures
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Uncontrollable movements of face, tongue, or limbs
If experiencing severe symptoms, call emergency services immediately.
What is anzol dp 10mg/20mg tablet used for?
This medicine is a combination of Domperidone 10 mg and Pantoprazole 20 mg used to treat acid reflux, GERD, and functional dyspepsia. It works by improving stomach emptying and reducing acid production. It is usually taken once daily before breakfast. Do not use without a prescription.
- Generic Name: Domperidone + Pantoprazole
- Manufacturer: Anant Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anzol dp 10mg/20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन 10 मिलीग्राम और पैंटोप्राजोल 20 मिलीग्राम का संयोजन है। इसका उपयोग एसिड रिफ्लक्स, गैस्ट्रोएसोफेजियल रिफ्लक्स डिजीज (GERD), अपच, और मतली जैसी समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करने और पेट खाली होने की प्रक्रिया को तेज करने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, सिरदर्द, दस्त, पेट दर्द, मतली और चक्कर आना शामिल हैं। कुछ लोगों को स्तन में कोमलता या सूजन हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि दिल की धड़कन अनियमित हो, गंभीर एलर्जी हो, या मैग्नीशियम का स्तर कम हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर नाश्ते से पहले एक बार। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। शराब से बचें क्योंकि इससे पेट की जलन और चक्कर बढ़ सकते हैं। यदि आपको दिल, लीवर, या किडनी की समस्या है तो डॉक्टर को बताएं। एंटासिड को इस दवा से 2 घंटे पहले या बाद में लें। बच्चों की पहुंच से दूर रखें।
💊 anzol dp 10mg/20mg tablet Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux symptoms such as heartburn and regurgitation by decreasing stomach acid production and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve post-meal fullness, upper abdominal bloating, and nausea when these symptoms are associated with delayed gastric emptying.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with acid-related disorders","description":"Domperidone component helps control nausea and vomiting, while pantoprazole treats the underlying acid problem.","evidence":"Moderate"},{"condition":"Gastritis with dyspeptic symptoms","description":"Used short-term to reduce acid-related inflammation and associated nausea or bloating.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in diabetic patients with delayed stomach emptying.","evidence":"Limited"},{"condition":"Refractory nausea in palliative care","description":"Domperidone component may be used off-label for nausea in palliative settings, but pantoprazole is not typically indicated for this purpose alone.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastritis, Nausea and vomiting associated with acid-related disorders
📋 Drug Information
| Generic Name(s) | Domperidone + Pantoprazole |
| Brand Name | Anleo-DSR Capsule |
| Manufacturer | Anant Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Domperidone is a peripheral dopamine D2 receptor antagonist that increases gastric and duodenal peristalsis, accelerates gastric emptying, and relaxes the pyloric sphincter. It also acts on the chemoreceptor trigger zone outside the blood-brain barrier to reduce nausea and vomiting. Pantoprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, thereby suppressing both basal and stimulated gastric acid secretion. Together, they reduce acid exposure and improve upper gastrointestinal motility.
Mechanism Steps
💡 How to Take anzol dp 10mg/20mg tablet
Strength: Immediate-release tablet containing Domperidone 10 mg and Pantoprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily before breakfast. However, the dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose. For GERD, treatment is typically continued for 4 to 8 weeks. For functional dyspepsia, shorter courses may be used. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of domperidone, especially QT prolongation and extrapyramidal symptoms. Use with caution and monitor closely. Dose adjustment may be needed based on renal and hepatic function. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance less than 30 mL/min), domperidone should be used with caution and the dose may need to be reduced. Pantoprazole does not require dose adjustment in renal impairment. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is usually needed. In severe hepatic impairment, domperidone is contraindicated, and pantoprazole should be used with caution. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Domperidone 10 mg + Pantoprazole 20 mg) per day. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anzol dp 10mg/20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Warfarin | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Major | |
| Atazanavir | Moderate | |
| Digoxin | Moderate | |
| Fluconazole | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Rifampicin | Moderate |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Methotrexate
- Warfarin
⚡ Moderate Interactions
- Atazanavir, nelfinavir
- Clopidogrel
- Digoxin
- Fluconazole
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase stomach acid, worsen reflux symptoms, and add to dizziness or drowsiness caused by domperidone. It may also increase the risk of gastrointestinal bleeding.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone, pantoprazole, or any component of the formulation","Prolactin-releasing pituitary tumor (prolactinoma)","Gastrointestinal bleeding, mechanical obstruction, or perforation","Severe hepatic impairment","Concomitant use with strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, or ritonavir","Known QT prolongation or family history of long QT syndrome","Concomitant use with QT-prolonging drugs"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease or risk factors for QT prolongation.","Avoid in patients with electrolyte disturbances (hypokalemia, hypomagnesemia) until corrected.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Long-term use of pantoprazole may increase the risk of bone fractures, hypomagnesemia, and vitamin B12 deficiency.","Use with caution in patients with liver disease; dose adjustment may be needed.","Use with caution in patients with kidney disease; dose adjustment may be needed for domperidone.","Do not use for more than 12 weeks without medical review.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Domperidone passes into breast milk and may cause side effects in the nursing infant. Pantoprazole may also pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, extrapyramidal symptoms, and QT prolongation. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be considered if taken recently. ECG monitoring is recommended. There is no specific antidote for domperidone or pantoprazole.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily before breakfast. Swallow the tablet whole with water; do not crush or chew. Avoid alcohol because it can worsen stomach irritation and increase dizziness. Do not drive or operate heavy machinery if you feel dizzy or sleepy. Inform your doctor if you have heart problems, liver disease, kidney disease, or low magnesium levels. Do not take antacids within two hours of this medicine. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of QT prolongation, electrolyte imbalances, and drug interactions. Use with caution and monitor renal and hepatic function. Dose adjustment may be needed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Both domperidone and pantoprazole should be used during pregnancy only if clearly needed. Discuss alternative treatments if necessary.
🏥 Post-Surgery Considerations
Consult your surgeon before taking this medicine after surgery. It may affect gastric motility and acid secretion, which could impact postoperative recovery. Use only if prescribed.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may increase the risk of bleeding during dental procedures if you are also on blood thinners. No specific precautions are otherwise needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid vigorous exercise immediately after meals as it can worsen reflux. Light walking after meals may aid digestion. If you experience dizziness or palpitations, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually taken once daily before breakfast, so it should not interfere with your work schedule. Inform your employer if you operate machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as irregular heartbeat, severe allergic reaction, or signs of low magnesium, seek immediate medical attention. Your doctor may taper the dose or switch to an alternative.
📅 Long-Term Use Effects
Long-term use of pantoprazole may lead to low magnesium levels, vitamin B12 deficiency, increased risk of bone fractures, and Clostridium difficile infection. Domperidone long-term use may cause breast changes and, rarely, cardiac arrhythmias. Regular monitoring and periodic review are recommended if used for more than 12 weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedOmeprazole, esomeprazole, or rabeprazole may be used instead of pantoprazole.
Evidence: Well-establishedRanitidine or famotidine may be used for milder acid suppression.
Evidence: Well-establishedMetoclopramide or domperidone alone may be used for motility disorders.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, long-term use of pantoprazole may increase the risk of infections; ensure routine vaccinations are up to date.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, continue taking it once daily before breakfast as per your new local time. Check customs regulations for carrying prescription medicines. Keep enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Domperidone starts working within 30-60 minutes to relieve nausea, while pantoprazole may take 2-4 days for full acid-suppressive effect. Symptom relief may begin within 1-2 days.
A: It is best taken on an empty stomach, at least 30 minutes before breakfast. Food may delay absorption of pantoprazole.
A: If you remember within 12 hours, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Consult your doctor before taking this medicine during pregnancy. It should be used only if clearly needed.
A: Do not stop without consulting your doctor. Abrupt discontinuation may cause rebound acid hypersecretion.
🤔 Common Patient Concerns
🔄 Substitutes for anzol dp 10mg/20mg tablet
View AllAlternative brands with exact same active ingredient:
-
pentoza d 10mg/20mg tabletZydus Cadila ₹11.25 62.5% CHEAPER
-
pantocalm d 10 mg/20 mg capsuleSun Pharmaceutical Industries Ltd ₹23.44 21.9% CHEAPER
-
Sydom D 10mg/20mg TabletCytochem Health Care India Pvt Ltd ₹25.78 14.1% CHEAPER
-
panter d tabletEthicare Pharma ₹32.81 9.4% COSTLIER
-
pancer dm 10mg/20mg capsuleMediwin Pharmaceuticals ₹33.75 12.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any stomach problem.
Fact: It is specifically for acid reflux and related conditions. It is not effective for all stomach issues and should only be used as prescribed. - Myth: It is safe to take indefinitely.
Fact: Long-term use requires medical supervision due to potential risks like low magnesium, vitamin B12 deficiency, and bone fractures. - Myth: It can be taken with alcohol without any issues.
Fact: Alcohol can worsen side effects and should be avoided. - Myth: It is safe to double the dose if symptoms are severe.
Fact: Never double the dose. Taking more than prescribed can increase the risk of serious side effects.
🔄 Alternative Options
Generic Alternatives
- Domperidone 10 mg + Pantoprazole 20 mg tablet (generic)
Brand Alternatives
- Dompan Tablet