ancold syrup - Paracetamol (125mg/5ml) + Pseudoephedrine (15mg/5ml) medicine

Ancold Syrup: Complete Medicine Guide

No reviews yet
🏭 Anant Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is ancold syrup used for?

This medicine is a combination of paracetamol and pseudoephedrine used for temporary relief of nasal congestion, headache, and fever due to cold or allergies. It works by reducing pain and fever and shrinking nasal blood vessels.

  • Generic Name: Paracetamol + Pseudoephedrine
  • Manufacturer: Anant Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ancold syrup के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और स्यूडोएफेड्रिन का संयोजन है, जिसका उपयोग सर्दी, एलर्जी या साइनसाइटिस के कारण होने वाली नाक की भीड़, सिरदर्द और बुखार से राहत के लिए किया जाता है। यह दर्द और बुखार को कम करने और नाक के रक्त वाहिकाओं को सिकोड़ने में मदद करती है।

साइड इफेक्ट्स: सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, जी मिचलाना और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दिल की धड़कन तेज होना और पेशाब में कठिनाई हो सकती है।

सुरक्षा सलाह: दवा की खुराक से अधिक न लें। इस दवा के साथ शराब न पिएं। बिना डॉक्टर की सलाह के 5-7 दिनों से अधिक उपयोग न करें। अन्य दवाओं में पैरासिटामोल की मात्रा की जाँच करें। उच्च रक्तचाप, हृदय रोग, मधुमेह या थायरॉइड विकार वाले रोगियों में सावधानी बरतें। बच्चों की पहुँच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ancold syrup Uses & Benefits

[{"condition":"Common cold with nasal congestion","description":"Relieves nasal stuffiness, headache, and fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces nasal congestion and sinus pressure in allergic rhinitis.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Provides symptomatic relief of sinus congestion and pain.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold

Also treats: Allergic rhinitis, Sinusitis

📋 Drug Information

Generic Name(s)Paracetamol + Pseudoephedrine
Brand NameActifed Plus Tablet
ManufacturerAnant Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAnalgesic, Antipyretic, Decongestant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine contains paracetamol which reduces fever.
Likely Use
✅
Headache
This medicine contains paracetamol which relieves headache.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and completely absorbed from the gastrointestinal tract. Pseudoephedrine is also well absorbed from the gastrointestinal tract.
DistributionParacetamol distributes widely into body tissues. Pseudoephedrine distributes into body tissues and crosses the blood-brain barrier.
Protein BindingParacetamol: 10-25%; Pseudoephedrine: Not established from the available information.
MetabolismParacetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction via CYP2E1 to N-acetyl-p-benzoquinone imine (NAPQI). Pseudoephedrine undergoes minimal hepatic metabolism.
Half-LifeParacetamol: 2-3 hours; Pseudoephedrine: 3-6 hours.
ExcretionParacetamol metabolites are excreted in urine. Pseudoephedrine is excreted largely unchanged in urine.
BioavailabilityParacetamol: 80-100%; Pseudoephedrine: Not established from the available information.
Onset of ActionParacetamol: 30-60 minutes; Pseudoephedrine: 15-30 minutes.
Peak Plasma TimeParacetamol: 0.5-2 hours; Pseudoephedrine: 1-2 hours.
Duration of ActionParacetamol: 4-6 hours; Pseudoephedrine: 4-6 hours.

How It Works

Paracetamol acts centrally to inhibit prostaglandin synthesis, thereby reducing pain and fever. Pseudoephedrine is a sympathomimetic amine that directly stimulates alpha-adrenergic receptors in the nasal mucosa, causing vasoconstriction and reduced nasal congestion.

Mechanism Steps

1
Paracetamol central action: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain and fever.
2
Pseudoephedrine alpha-adrenergic stimulation: Pseudoephedrine binds to alpha-adrenergic receptors on nasal blood vessels, causing vasoconstriction.
3
Reduced nasal congestion: Vasoconstriction decreases blood flow to the nasal mucosa, reducing swelling and congestion.

💡 How to Take ancold syrup

Strength: Each 5 ml contains Paracetamol 125 mg and Pseudoephedrine 15 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally with or without food.
4Follow the prescribed dose and duration.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 10 ml (2 teaspoons) every 4-6 hours as needed, not to exceed 4 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of pseudoephedrine and paracetamol. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseParacetamol: 4 grams per day; Pseudoephedrine: 240 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ancold syrup

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.
Restlessness (Common (5-10%))
Avoid taking close to bedtime. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or trouble breathing.
Palpitations (Rare (<0.1%))
Consult a doctor if you feel rapid, pounding, or irregular heartbeat.
Difficulty in urination (Rare (<0.1%))
Consult a doctor if you have trouble passing urine.

⚠️ Rare Side Effects

Liver damage (paracetamol overdose)
Seek immediate medical attention if you experience yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Beta-blockers Major
Tricyclic antidepressants Moderate
Digoxin Moderate
Antihistamines Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Beta-blockers

⚡ Moderate Interactions

  • Tricyclic antidepressants
  • Digoxin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase the risk of liver damage from paracetamol and enhance drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe hypertension","Coronary artery disease","Hyperthyroidism","Concurrent use of MAOIs","Severe liver disease","Known hypersensitivity to any component"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose.","Avoid alcohol.","Use with caution in patients with cardiovascular disease, diabetes, or thyroid disorders.","May cause drowsiness; avoid driving or operating machinery.","Do not use for more than 5-7 days without consulting a doctor.","Keep out of reach of children."]

🤱 Lactation Safety

Paracetamol is considered safe during breastfeeding. Pseudoephedrine may pass into breast milk and can cause irritability in the infant. Consult your doctor before use.

💊 Overdose Management

Seek immediate medical attention. Overdose can cause severe liver damage from paracetamol and serious cardiovascular effects from pseudoephedrine. Treatment is supportive and may include activated charcoal, acetylcysteine for paracetamol toxicity, and management of hypertension.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose. Avoid alcohol while taking this medicine. Do not use for more than 5-7 days without consulting a doctor. Check other medications for paracetamol content to avoid overdose. Use with caution in patients with high blood pressure, heart disease, diabetes, or thyroid disorders. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of pseudoephedrine and paracetamol. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy or are pregnant. Paracetamol is generally considered safe, but pseudoephedrine should be used with caution.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

This medicine may cause drowsiness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine if symptoms persist beyond 7 days or if you experience any serious side effects. Consult your doctor before stopping if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of pseudoephedrine can lead to rebound congestion, and excessive paracetamol can cause liver damage. Regular monitoring of liver function may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Steam inhalation

May provide temporary relief from nasal congestion.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule accordingly, but do not exceed the maximum daily dose. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with common cold and nasal congestion
He took this medicine as directed and experienced significant relief from congestion and headache within 30 minutes. He was advised to take it with food to avoid stomach upset.
💡 Lesson: Taking this medicine with food improves tolerability and ensures better symptom relief.
👤 A 28-year-old woman with allergic rhinitis
She used this medicine for seasonal allergies and found relief from nasal stuffiness and sneezing. She was cautioned not to exceed the recommended dose and to avoid driving due to drowsiness.
💡 Lesson: Adhering to the prescribed dose and being aware of potential drowsiness is important for safety.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking a dose.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce the risk of stomach upset.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ancold syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It can be used for long-term nasal congestion.
    Fact: It is intended for short-term use only. Prolonged use can cause rebound congestion.
  • Myth: It is safe to take with other paracetamol-containing products.
    Fact: Taking multiple paracetamol products can lead to overdose and liver damage.

📊 Comparison with Similar Medicines

[]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory