antazer rd 30mg/40mg tablet - Uses, Price, Side Effects & Substitutes
What is antazer rd 30mg/40mg tablet used for?
Acera-D Capsule SR (Domperidone + Rabeprazole) is used to treat Gastroesophageal reflux disease (GERD). It contains Domperidone (30mg) + Rabeprazole (40mg), which Domperidone: Blocks dopamine D2 receptors in the chemoreceptor trigger zone and . Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone + Rabeprazole
- Manufacturer: Crassula Pharmaceuticals Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 antazer rd 30mg/40mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
antazer rd 30mg/40mg tablet का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Domperidone (30mg) + Rabeprazole (40mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Domperidone + Rabeprazole |
|---|---|
| Brand Name | Acera-D Capsule SR |
| Manufacturer | Crassula Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take antazer rd 30mg/40mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture.
⚙️ How antazer rd 30mg/40mg tablet Works
Domperidone: Blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, enhancing gastric motility and emptying. Rabeprazole: Irreversibly inhibits H+/K+ ATPase (proton pump) in gastric parietal cells, reducing gastric acid secretion.
💊 antazer rd 30mg/40mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
⚠️ What are the side effects of antazer rd 30mg/40mg tablet?
✅ Common Side Effects
- Headache
- Diarrhea
- Constipation
- Abdominal pain
- Nausea
- Dry mouth
🚨 Serious Side Effects
- QT prolongation
- Ventricular arrhythmias
- Torsades de pointes
- Gynecomastia
- Galactorrhea
- Liver injury
⚠️ Rare Side Effects
- Extrapyramidal symptoms
- Hyperprolactinemia
- Interstitial nephritis
- Clostridium difficile infection
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation and arrhythmias |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Digoxin | Moderate | Increased digoxin levels |
| Antacids | Minor | Reduced absorption of rabeprazole |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- CYP2C19 inhibitors (e.g., fluconazole)
- QT-prolonging drugs (e.g., amiodarone, moxifloxacin)
⚡ Moderate Interactions
- Antacids
- Sucralfate
- Digoxin
- Methotrexate
ℹ️ Minor Interactions
- Caffeine
- Theophylline
🍽️ Food Interactions
Food may delay absorption of domperidone; rabeprazole absorption unaffected by food.
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to domperidone or rabeprazole; gastrointestinal hemorrhage, obstruction, or perforation; prolactinoma; concomitant use with QT-prolonging drugs or strong CYP3A4 inhibitors.
📊 Monitoring Parameters
ECG for QT interval; liver function tests; renal function; serum electrolytes.
🤱 Lactation Safety
Domperidone: Excreted in breast milk, may cause adverse effects; Rabeprazole: Excreted in breast milk, use with caution.
💊 Overdose Management
Symptomatic and supportive treatment; gastric lavage; monitoring of ECG for QT prolongation.
⏰ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
🛑 Myths vs. Facts about antazer rd 30mg/40mg tablet
- Myth: Generic substitutes of antazer rd 30mg/40mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Domperidone (30mg) + Rabeprazole (40mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of antazer rd 30mg/40mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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