Anogyl-F Tablet - Uses, Price, Side Effects
What is anogyl-f tablet used for?
Anogyl-F Tablet is a combination of Furazolidone and Metronidazole used to treat diarrhea and dysentery caused by bacterial or protozoal infections. Furazolidone works by inhibiting bacterial enzymes, while Metronidazole kills parasites and anaerobic bacteria, together stopping the infection and relieving symptoms.
- Generic Name: Furazolidone + Metronidazole
- Manufacturer: Anoco Pharmaceuticals India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ anogyl-f tablet Uses & Benefits
Diarrhea, dysentery, giardiasis, amebiasis, bacterial enteritis
Off-label uses: Helicobacter pylori eradication (in combination), Tropical sprue
๐ Drug Information
| Generic Name(s) | Furazolidone + Metronidazole |
| Brand Name | Aristogyl-F Oral Suspension |
| Manufacturer | Anoco Pharmaceuticals India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibacterial, Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store below 30ยฐC, protect from light, do not freeze |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Furazolidone: inhibits bacterial monoamine oxidase and disrupts bacterial DNA synthesis; Metronidazole: undergoes reduction by bacterial nitroreductases, forming toxic metabolites that damage DNA
Mechanism Steps
๐ก How to Take anogyl-f tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of anogyl-f tablet
โ Common Side Effects
- Nausea
- Vomiting
- Metallic taste
- Anorexia
- Diarrhea
- Headache
๐จ Serious Side Effects
- Peripheral neuropathy
- Seizures
- Leukopenia
- Hepatitis
- Disulfiram-like reaction with alcohol
โ ๏ธ Rare Side Effects
- Pancreatitis
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Carcinogenicity (animal studies)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Disulfiram-like reaction (nausea, vomiting, headache) |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Phenytoin | Moderate | Increased phenytoin levels |
๐จ Major Interactions
- Disulfiram
- Warfarin
- Alcohol
- MAOIs
- Linezolid
โก Moderate Interactions
- Phenytoin
- Lithium
- Cyclosporine
- Fluorouracil
โน๏ธ Minor Interactions
- Cimetidine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Avoid tyramine-rich foods (aged cheese, cured meats) due to MAOI effect of furazolidone
๐ท Alcohol Interaction
Disulfiram-like reaction (nausea, vomiting, headache) with metronidazole; avoid alcohol during and 48 hours after therapy
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to nitroimidazoles or furazolidone; concurrent use of alcohol or disulfiram; MAOI therapy within 14 days; pregnancy (first trimester) unless essential
๐ Monitoring Parameters
CBC, liver function tests, neurological symptoms (peripheral neuropathy)
๐คฑ Lactation Safety
Metronidazole excreted in breast milk; avoid breastfeeding during therapy and for 24 hours after las
๐ Overdose Management
Gastric lavage, symptomatic and supportive treatment; no specific antidote
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose