anilide p 100mg/500mg tablet - Nimesulide (100mg) + Paracetamol (500mg) medicine

Anilide P 100mg/500mg Tablet - Uses, Price, Side Effects

4.6 (16 reviews)
๐Ÿญ Anikem Laboratories ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is anilide p 100mg/500mg tablet used for?

Anilide P 100mg/500mg Tablet is a combination medicine containing Nimesulide and Paracetamol. It is used to relieve pain and reduce fever in conditions like headache, toothache, menstrual cramps, and musculoskeletal pain. Nimesulide works by reducing inflammation, while Paracetamol acts on the brain to lower fever and pain perception.

  • Generic Name: Nimesulide + Paracetamol
  • Manufacturer: Anikem Laboratories
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š anilide p 100mg/500mg tablet Uses & Benefits

Acute pain, fever, inflammatory conditions

Off-label uses: Dysmenorrhea, dental pain

๐Ÿ“‹ Drug Information

Generic Name(s)Nimesulide + Paracetamol
Brand NameAP 100mg/325mg Tablet
ManufacturerAnikem Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses placenta and enters breast milk
Protein BindingNimesulide: >97.5%; Paracetamol: 10-25%
MetabolismNimesulide: Hepatic via CYP2C9; Paracetamol: Hepatic via glucuronidation, sulfation, and CYP2E1
Half-LifeNimesulide: 1.8-4.7 hours; Paracetamol: 1.5-3 hours
ExcretionNimesulide: Renal (50%), fecal (29%); Paracetamol: Renal (90-100%)
BioavailabilityNimesulide: ~100%; Paracetamol: 60-90%
Onset of ActionNimesulide: 15-30 minutes; Paracetamol: 30-60 minutes
Peak Plasma TimeNimesulide: 1-3 hours; Paracetamol: 30-60 minutes
Duration of ActionNimesulide: 6-8 hours; Paracetamol: 4-6 hours

How It Works

Nimesulide selectively inhibits COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, reducing pain and fever

Mechanism Steps

1Nimesulide selectively inhibits COX-2 enzyme, reducing prostaglandin synthesis at sites of inflammation
2Paracetamol inhibits COX in the central nervous system, reducing pain and fever
3Decreased prostaglandins lead to reduced pain perception and inflammation

๐Ÿ’ก How to Take anilide p 100mg/500mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โœ… ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of anilide p 100mg/500mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Somnolence
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Gastrointestinal bleeding
  • Stevens-Johnson syndrome
  • Renal failure

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Methotrexate Major Increased methotrexate toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; avoid alcohol

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity and gastrointestinal bleeding

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, lactation, children <12 years (Nimesulide)

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, blood pressure, signs of bleeding

๐Ÿคฑ Lactation Safety

Paracetamol is safe; Nimesulide is contraindicated

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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