anifer syrup - Iron Hydroxide Polymaltose (50mg) medicine

Anifer Syrup: Comprehensive Guide to Uses, Dosage, and Safety

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🏭 Smilax Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Iron supplementation is generally considered safe and often necessary during pregnancy to prevent and treat iron deficiency anemia. This medicine should be used under the supervision of a healthcare provider who can determine the appropriate dose based on the mother's iron status. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for the treatment of iron deficiency anemia.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Difficulty breathing or swelling of face, lips, or throat
  • High fever with rash
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is anifer syrup used for?

This medicine is an oral iron supplement used to treat and prevent iron deficiency anemia. It contains iron hydroxide polymaltose complex, which replenishes iron stores and supports red blood cell production. It is generally well tolerated and should be taken as prescribed by a doctor.

  • Generic Name: Iron Hydroxide Polymaltose
  • Manufacturer: Smilax Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anifer syrup के बारे में (Hindi Summary)

उपयोग: यह दवा आयरन की कमी से होने वाले एनीमिया (खून की कमी) के इलाज और रोकथाम के लिए दी जाती है। यह शरीर में आयरन की मात्रा बढ़ाकर लाल रक्त कोशिकाओं के निर्माण में मदद करती है, जिससे थकान, कमजोरी और पीलापन जैसे लक्षणों में सुधार होता है। यह गर्भवती महिलाओं, बच्चों और उन लोगों के लिए फायदेमंद है जिनमें आयरन की कमी है। इस दवा को डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे मतली, कब्ज, दस्त, पेट में असहजता, या मुँह में धातु जैसा स्वाद। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। मल का रंग काला हो सकता है, जो सामान्य है और चिंता की बात नहीं है। यदि आपको गंभीर एलर्जी, सांस लेने में कठिनाई, या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इसे डॉक्टर के बताए अनुसार ही लें, खुद से मात्रा न बढ़ाएं। इसे भोजन के साथ या तुरंत बाद लें ताकि पेट में जलन न हो। एंटासिड, कैल्शियम सप्लीमेंट, और कुछ एंटीबायोटिक्स के साथ इस दवा को न लें, क्योंकि इससे आयरन का अवशोषण कम हो सकता है। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। नियमित रूप से खून की जांच कराते रहें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 anifer syrup Uses & Benefits

[{"condition":"Iron deficiency anemia","description":"This medicine is used to treat iron deficiency anemia by replenishing iron stores and supporting red blood cell production.","evidence":"Well-established"},{"condition":"Prevention of iron deficiency","description":"This medicine may be prescribed to prevent iron deficiency in individuals at high risk, such as pregnant women, vegetarians, and those with chronic blood loss.","evidence":"Well-established"},{"condition":"Anemia of chronic disease","description":"This medicine can be used as part of the management of anemia associated with chronic conditions like kidney disease or inflammatory disorders, under medical supervision.","evidence":"Moderate"},{"condition":"Post-hemorrhagic anemia","description":"This medicine helps restore iron levels after significant blood loss due to surgery, trauma, or heavy menstrual bleeding.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Restless legs syndrome","description":"Iron supplementation may be used off-label to alleviate symptoms of restless legs syndrome in patients with low ferritin levels, but this should only be done under medical supervision.","evidence":"Limited"},{"condition":"Fatigue without anemia","description":"Some healthcare providers may prescribe iron supplements for unexplained fatigue even when anemia is not present, but evidence for this practice is limited.","evidence":"Limited"}]

Primary treatment for: Iron deficiency anemia

Also treats: Anemia of chronic disease, Post-hemorrhagic anemia, Nutritional iron deficiency

📋 Drug Information

Generic Name(s)Iron Hydroxide Polymaltose
Brand NameAnifer Syrup
ManufacturerSmilax Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassHaemopoetic agents
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineThe World Health Organization recommends iron supplementation for the prevention and treatment of iron deficiency anemia in at-risk populations, including pregnant women and young children. However, specific dosing should be individualized.
ICMR GuidelineThe Indian Council of Medical Research recommends iron and folic acid supplementation for the prevention and treatment of anemia in India, particularly for women of reproductive age and children. This medicine may be used as part of such programs under medical supervision.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid taking this medicine with tea, coffee, or dairy products as they can reduce iron absorption.
3
Separate this medicine from antacids, calcium supplements, and certain antibiotics by at least 2 hours.
4
Dark stools are a common and harmless effect of iron supplements; do not be alarmed.
5
Complete the full course as prescribed, even if you start feeling better, to replenish iron stores.
6
Keep this medicine out of reach of children to prevent accidental overdose.
7
Inform your doctor if you experience severe constipation or diarrhea that does not improve.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fatigue and weakness
This medicine is commonly prescribed for fatigue due to iron deficiency.
Likely Use
✅
Pale skin
This medicine helps improve hemoglobin levels, which can improve skin color.
Likely Use
✅
Shortness of breath
Iron deficiency anemia can cause shortness of breath; this medicine may help.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThe iron hydroxide polymaltose complex in this medicine is absorbed in the small intestine. The absorption is regulated by the body's iron needs, with higher absorption when iron stores are low and lower absorption when stores are adequate. This medicine is designed to provide a gradual release of iron, which may enhance tolerability.
DistributionAfter absorption, iron is transported in the blood bound to transferrin and distributed to various tissues, particularly the bone marrow, liver, spleen, and muscles. It is incorporated into haemoglobin, myoglobin, and enzymes.
Protein BindingIron in the bloodstream is bound to transferrin, a plasma protein that transports iron to tissues. The polymaltose complex itself does not bind to plasma proteins.
MetabolismIron is not metabolized in the traditional sense; instead, it is stored and recycled in the body. The polymaltose component is likely broken down and excreted.
Half-LifeNot established from the available information.
ExcretionIron is primarily excreted through the feces, urine, and sweat, but the body tightly regulates iron balance, and most iron is recycled. Unabsorbed iron from this medicine is excreted in the stool.
BioavailabilityThe bioavailability of iron from iron hydroxide polymaltose complex is generally lower than that of ferrous salts, but it is designed to be better tolerated. Bioavailability is influenced by individual iron status and other dietary factors.
Onset of ActionImprovement in symptoms of anemia such as fatigue and weakness may begin within a few weeks of starting this medicine, but normalization of hemoglobin levels typically takes several weeks to months.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effects of this medicine are sustained as long as it is taken regularly. It may take several months to replenish iron stores completely.

How It Works

This medicine works by providing a stable complex of iron hydroxide polymaltose, which is absorbed in the small intestine and transported to the bone marrow and other tissues. Once inside the body, the iron is released from the polymaltose complex and incorporated into haemoglobin, myoglobin, and various enzymes. This process helps to increase the oxygen-carrying capacity of the blood and supports essential metabolic functions. The polymaltose component allows for gradual release of iron, which improves tolerability and reduces the risk of gastrointestinal irritation compared to conventional iron salts.

Mechanism Steps

1
Ingestion and dissolution: This medicine is swallowed as a syrup, and the iron hydroxide polymaltose complex dissolves in the gastrointestinal fluids.
2
Absorption in the small intestine: The iron complex is absorbed primarily in the duodenum and upper jejunum through active and passive transport mechanisms.
3
Release of iron: Inside the intestinal cells, iron is released from the polymaltose complex and enters the bloodstream via transferrin.
4
Transport to bone marrow: Transferrin carries iron to the bone marrow, where it is used for the synthesis of haemoglobin in developing red blood cells.
5
Storage and utilization: Excess iron is stored in the liver, spleen, and bone marrow as ferritin and hemosiderin, and is mobilized when needed.

💡 How to Take anifer syrup

Strength: Syrup containing 50 mg of iron hydroxide polymaltose per 5 mL (or as specified on the label).

1Shake the bottle well before each use.
2Use the measuring cup or dropper provided to measure the exact dose prescribed.
3Take this medicine orally, with or without food, but preferably with food to reduce stomach upset.
4Swallow the syrup directly; do not mix with other liquids unless instructed by your doctor.
5Follow your doctor's instructions regarding the timing and duration of therapy.
6Do not exceed the recommended dose.

Dosage Information

Adult DosageThe adult dosage of this medicine is individualized by a qualified clinician based on the severity of iron deficiency, the patient's age, weight, and renal and hepatic function. Typically, for the treatment of iron deficiency anemia, a common dose is 50-100 mg of elemental iron two to three times daily, but the exact dose and duration must be determined by your doctor. For prevention, a lower dose may be used. Always follow your doctor's prescription and do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may require dose adjustments based on renal and hepatic function and overall health status. Use with caution and under medical supervision.
Renal ImpairmentPatients with renal impairment may need dose adjustments and close monitoring. Consult a nephrologist or your doctor for guidance.
Hepatic ImpairmentPatients with hepatic impairment should use this medicine with caution and under medical supervision, as iron metabolism may be affected.
Maximum Daily DoseThe maximum daily dose should not exceed the amount prescribed by your doctor. Generally, for adults, the maximum elemental iron dose for treatment is around 200 mg per day, but this must be individualized.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Tea/coffee
Avoid taking together
Tannins reduce iron absorption.
Dairy
Separate by 2 hours
Calcium inhibits iron absorption.
Vitamin C-rich foods
Take together
Enhances iron absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anifer syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take this medicine with food to reduce nausea. If it persists, consult your doctor.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult your doctor if constipation is severe or persistent.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or lasts more than a few days, contact your doctor.
Stomach discomfort (Common (5-10%))
Take with meals. If discomfort continues, speak to your doctor.
Metallic taste (Common (5-10%))
This usually goes away with continued use. Chewing sugar-free gum may help.
Dark stools (Common (5-10%))
This is harmless and expected. No action needed.

🚨 Serious Side Effects

Allergic reaction (rash, itching, swelling) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, or throat, or difficulty breathing.
Severe abdominal pain (Rare (<0.1%))
Stop this medicine and consult a doctor immediately.
Vomiting blood or black, tarry stools (Rare (<0.1%))
This may indicate gastrointestinal bleeding. Seek emergency care.
Iron overload (hemochromatosis) (Rare (<0.1%))
Symptoms include joint pain, fatigue, and skin discoloration. Requires immediate medical evaluation.

⚠️ Rare Side Effects

Anaphylaxis
Call emergency services immediately if you experience difficulty breathing, severe dizziness, or loss of consciousness.
Seizures
Seek emergency medical help if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Quinolones Major
Levothyroxine Major
Methyldopa Major
Antacids Moderate
Calcium supplements Moderate
Proton pump inhibitors Moderate
Tea/coffee Minor
Vitamin C Minor
Alcohol Moderate

🚨 Major Interactions

  • Tetracycline antibiotics
  • Quinolone antibiotics
  • Levothyroxine
  • Methyldopa

⚡ Moderate Interactions

  • Antacids
  • Calcium supplements
  • Proton pump inhibitors

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal irritation and can worsen iron overload in susceptible individuals. It is advisable to avoid alcohol while taking this medicine, especially if you have liver disease or a history of alcohol abuse.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to iron hydroxide polymaltose or any component of this medicine","Iron overload conditions such as hemochromatosis or hemosiderosis","Hemolytic anemia not related to iron deficiency","Repeated blood transfusions without iron deficiency","Concurrent use with parenteral iron preparations"]

⚠️ Warnings & Precautions

["This medicine should be kept out of reach of children to prevent accidental overdose, which can be fatal.","Do not exceed the recommended dose without medical advice.","Use with caution in patients with gastrointestinal disorders such as peptic ulcer or inflammatory bowel disease.","Iron supplements can cause dark stools, which is harmless but may mask gastrointestinal bleeding.","Patients with diabetes should note that this syrup may contain sugar or sorbitol; check with your doctor.","Regular monitoring of iron status is recommended during prolonged therapy.","Avoid taking this medicine with antacids, calcium, or certain antibiotics as they can reduce absorption.","If you experience signs of allergic reaction, stop this medicine and seek medical help immediately."]

🤱 Lactation Safety

Iron is excreted in breast milk in small amounts and is generally considered safe during breastfeeding. However, consult your doctor before using this medicine while nursing to ensure it is appropriate for your situation.

💊 Overdose Management

Overdose of iron-containing products can be serious, especially in children. Symptoms of overdose include severe abdominal pain, vomiting, bloody diarrhea, dehydration, and shock. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include gastric lavage, supportive care, and administration of chelating agents such as deferoxamine. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before starting this medicine, inform your doctor about all your medical conditions, especially if you have a history of iron overload disorders, liver disease, kidney disease, or any allergies. This medicine should be taken exactly as prescribed by your healthcare provider, and you should not exceed the recommended dose without medical advice. Take this medicine with food or immediately after a meal to minimize stomach upset, unless your doctor advises otherwise. Avoid taking this medicine at the same time as antacids, calcium supplements, or certain antibiotics such as tetracyclines and quinolones, as they can reduce iron absorption. Keep this medicine out of the reach of children to prevent accidental overdose, which can be dangerous. If you are pregnant or breastfeeding, consult your doctor before using this medicine to ensure it is safe for you and your baby. Regular blood tests may be needed to monitor your hemoglobin levels and iron stores while you are on this medicine. Do not use this medicine for longer than recommended without consulting your doctor, as prolonged use without monitoring can lead to iron overload. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to gastrointestinal side effects and should use this medicine with caution. Dose adjustments may be necessary based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, discuss your iron status with your doctor. Adequate iron levels are important for a healthy pregnancy. This medicine may be prescribed to prevent or treat iron deficiency.

🏥 Post-Surgery Considerations

After surgery, iron levels may be low due to blood loss. This medicine may be prescribed to help restore iron stores. Follow your surgeon's instructions regarding when to resume oral iron.

🦷 Dental Procedures

No specific precautions are needed for dental procedures while taking this medicine. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Include iron-rich foods like leafy greens, beans, and lean meats in your diet.
🥗
Pair iron-rich foods with vitamin C sources to enhance absorption.
😴
Avoid drinking tea or coffee with meals as they inhibit iron absorption.
💧
Maintain a healthy lifestyle with regular exercise and adequate sleep.
🧘
If you are pregnant, attend regular prenatal check-ups for monitoring.

🏋️ Exercise Considerations

No specific exercise restrictions are associated with this medicine. However, if you feel dizzy or weak due to anemia, avoid strenuous activities until your condition improves.

🥗 Diet Recommendations

Eat iron-rich foods such as spinach, lentils, and red meat.
Consume vitamin C-rich fruits like oranges and strawberries with meals.
Avoid tea, coffee, and calcium supplements close to the time of taking this medicine.
Stay hydrated to prevent constipation.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness or fatigue due to anemia, use caution when driving or operating machinery until you feel better.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Stopping prematurely may lead to recurrence of anemia. Your doctor will advise you on the appropriate duration based on your condition and blood test results.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when taken as prescribed and monitored. However, excessive iron intake can lead to iron overload, which may cause organ damage. Regular monitoring of iron levels and liver function is recommended for prolonged therapy. Do not continue this medicine beyond the recommended duration without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary iron supplementation

Increasing intake of iron-rich foods can help prevent and manage mild iron deficiency.

Evidence: Well-established
Intravenous iron therapy

For severe anemia or malabsorption, intravenous iron may be prescribed by a specialist.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If crossing time zones, continue taking it at your usual times; no adjustment is typically needed. Check customs regulations for carrying liquid medications. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with heavy menstrual bleeding and fatigue
She was diagnosed with iron deficiency anemia and prescribed this medicine. After taking it regularly with breakfast for three months, her hemoglobin levels improved significantly, and she felt more energetic. She noted that taking it with food helped prevent nausea.
💡 Lesson: Consistent use with food improves tolerability and effectiveness.
👤 A 45-year-old man with chronic kidney disease and anemia
He was prescribed this medicine as part of his anemia management. With regular monitoring and dose adjustment by his nephrologist, his iron levels stabilized, and he required fewer blood transfusions. He emphasized the importance of not missing doses.
💡 Lesson: Regular monitoring and adherence are key in managing anemia of chronic disease.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within a few weeks, but it can take several months to fully replenish iron stores and normalize hemoglobin levels.

Q: Can I take it with food?

A: Yes, taking it with food can reduce stomach upset. However, avoid taking it with tea, coffee, or dairy products as they can reduce absorption.

Q: Is it safe during pregnancy?

A: Iron supplements are often necessary during pregnancy. Consult your doctor for the appropriate dose.

Q: What are the side effects?

A: Common side effects include nausea, constipation, diarrhea, and dark stools. These are usually mild and temporary.

Q: Can I take it with other medicines?

A: Some medicines can interact with iron. Inform your doctor about all medications you are taking.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Iron supplements cause weight gain.
    Fact: Iron supplements do not cause weight gain. They may improve appetite in some individuals, but this is not a direct effect on weight.
  • Myth: You can stop taking iron supplements once you feel better.
    Fact: It is important to complete the full course as prescribed to replenish iron stores, even if symptoms improve.
  • Myth: All iron supplements are the same.
    Fact: Different iron formulations have varying absorption rates and tolerability profiles. This medicine contains iron hydroxide polymaltose, which is designed to be gentle on the stomach.

🔄 Alternative Options

Generic Alternatives

  • Iron hydroxide polymaltose complex syrup (generic versions)

Brand Alternatives

  • Anifer syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Iron hydroxide polymaltose)","active_ingredient":"Iron hydroxide polymaltose","strength":"50 mg","form":"Syrup","key_feature":"Gentle on stomach, gradual iron release"},{"medicine":"Ferrous sulfate","active_ingredient":"Ferrous sulfate","strength":"Varies","form":"Syrup/Tablet","key_feature":"High elemental iron, but more GI side effects"},{"medicine":"Ferrous fumarate","active_ingredient":"Ferrous fumarate","strength":"Varies","form":"Syrup/Tablet","key_feature":"Good absorption, moderate GI side effects"}]

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