anibutol 1000mg tablet

4.5 (17 reviews)

Ethambutol (1000mg)

🏭 Anikem Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is anibutol 1000mg tablet used for?

Actol 800mg Tablet (Ethambutol) is used to treat ANTI INFECTIVES. It contains Ethambutol (1000mg), which Inhibits arabinosyl transferase (emb) involved in cell wall synthesis of mycobac. Always consult your doctor before use. Take as prescribed.

Generic Name: Ethambutol
Manufacturer: Anikem Laboratories
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 anibutol 1000mg tablet Uses & Benefits

Treatment of tuberculosis (in combination with other antitubercular agents); atypical mycobacterial infections.

Off-label uses: Treatment of Mycobacterium avium complex (MAC) infection; prophylaxis in HIV patients.

📋 Drug Information

Generic Name(s)	Ethambutol
Brand Name	Actol 800mg Tablet
Manufacturer	Anikem Laboratories
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Mycobacterial cell wall inhibitors-Ethambutol
Route of Administration	Oral
Storage	Store at room temperature (20-25°C); protect from moisture and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract; peak plasma concentrations occur within 2-4 hours.

DistributionDistributed widely in body tissues and fluids; achieves high concentrations in erythrocytes and kidneys.

Protein Binding20-30%

MetabolismPartially metabolized in the liver to inactive metabolites (aldehyde and dicarboxylic acid derivatives).

Half-Life3-4 hours (can be prolonged in renal impairment)

ExcretionPrimarily excreted unchanged in urine (50-80%) via glomerular filtration and tubular secretion; also excreted in feces.

BioavailabilityApproximately 80%

Onset of ActionWithin 24 hours

Peak Plasma Time2-4 hours

Duration of ActionUp to 24 hours

How It Works

Inhibits arabinosyl transferase (emb) involved in cell wall synthesis of mycobacteria, leading to inhibition of cell wall formation.

Mechanism Steps

1Ethambutol enters mycobacterial cells via passive diffusion.

2It inhibits arabinosyl transferase (emb), an enzyme involved in polymerization of arabinogalactan.

3This disrupts cell wall synthesis by preventing formation of arabinogalactan-mycolic acid complex.

💡 How to Take anibutol 1000mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of anibutol 1000mg tablet

✅ Common Side Effects

Nausea
Vomiting
Abdominal pain
Headache
Dizziness
Rash

🚨 Serious Side Effects

Optic neuritis (decreased visual acuity, color blindness)
Peripheral neuropathy
Hepatotoxicity
Thrombocytopenia

⚠️ Rare Side Effects

Anaphylaxis
Stevens-Johnson syndrome
Lactic acidosis
Renal failure

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Aluminum hydroxide	Major	Decreased absorption of ethambutol
Isoniazid	Major	Increased risk of peripheral neuropathy
Rifampin	Major	Increased hepatotoxicity risk
Ethionamide	Moderate	Additive optic neuropathy risk
Pyrazinamide	Moderate	Increased hepatotoxicity risk
Probenecid	Minor	Decreased renal excretion of ethambutol

🚨 Major Interactions

Aluminum hydroxide
Isoniazid
Rifampin

⚡ Moderate Interactions

Ethionamide
Pyrazinamide

ℹ️ Minor Interactions

Probenecid

🍽️ Food Interactions

Food may decrease absorption; take on an empty stomach if possible.

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to ethambutol; optic neuritis; severe renal impairment (CrCl <10 mL/min).

📊 Monitoring Parameters

Visual acuity and color vision tests (baseline and monthly); renal function; liver function tests; serum uric acid.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Induce vomiting or gastric lavage; supportive care; monitor for optic toxicity and renal function.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

🔗 View Profile

🔄 Substitutes for anibutol 1000mg tablet

View All

Alternative brands with exact same active ingredient (Ethambutol (1000mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.