anglodom 1mg/ml drop - Uses, Price, Side Effects & Substitutes
What is anglodom 1mg/ml drop used for?
Actidom 5mg Oral Suspension (Domperidone) is used to treat GASTRO INTESTINAL. It contains Domperidone (1mg/ml), which Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chem. Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone
- Manufacturer: Anglo-French Drugs & Industries Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ anglodom 1mg/ml drop Uses & Benefits
๐ Drug Information
| Generic Name(s) | Domperidone |
| Brand Name | Actidom 5mg Oral Suspension |
| Manufacturer | Anglo-French Drugs & Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Dopamine (D2) receptor antagonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC). Protect from light and moisture. Keep bottle tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract. It blocks dopamine receptors, increasing lower esophageal sphincter pressure, enhancing gastric motility and peristalsis, and accelerating gastric emptying.
Mechanism Steps
๐ก How to Take anglodom 1mg/ml drop
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of anglodom 1mg/ml drop
โ Common Side Effects
- Dry mouth
- Headache
- Diarrhea
- Abdominal cramps
- Galactorrhea
- Gynecomastia
- Amenorrhea
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Cardiac arrest
- Extrapyramidal symptoms (dystonia, akathisia)
- Neuroleptic malignant syndrome (rare)
โ ๏ธ Rare Side Effects
- Allergic reactions (rash, urticaria)
- Seizures
- Hepatotoxicity
- Leukopenia
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation and cardiac arrhythmias |
| Erythromycin | Major | Increased risk of QT prolongation |
| Clarithromycin | Major | Increased risk of QT prolongation |
| Amiodarone | Major | Increased risk of QT prolongation |
| Quinidine | Major | Increased risk of QT prolongation |
| Fluconazole | Major | Increased risk of QT prolongation |
| Ritonavir | Major | Increased risk of QT prolongation |
| Saquinavir | Major | Increased risk of QT prolongation |
| Telaprevir | Major | Increased risk of QT prolongation |
| Voriconazole | Major | Increased risk of QT prolongation |
| Cimetidine | Moderate | Reduced absorption of domperidone |
| Ranitidine | Moderate | Reduced absorption of domperidone |
| Omeprazole | Moderate | Reduced absorption of domperidone |
| Phenothiazines | Moderate | Increased risk of extrapyramidal symptoms |
| Tricyclic antidepressants | Moderate | Increased risk of QT prolongation |
| SSRIs | Moderate | Increased risk of QT prolongation |
| MAOIs | Moderate | Increased risk of hypertensive crisis |
| Lithium | Moderate | Increased risk of extrapyramidal symptoms |
| Opioid analgesics | Moderate | Antagonism of gastrointestinal prokinetic effect |
| Anticholinergics | Moderate | Antagonism of gastrointestinal prokinetic effect |
| Aluminum-containing antacids | Minor | Reduced absorption of domperidone |
| Sucralfate | Minor | Reduced absorption of domperidone |
| Digoxin | Minor | Reduced absorption of digoxin |
| Paracetamol | Minor | No significant interaction |
| Diazepam | Minor | No significant interaction |
๐จ Major Interactions
- Ketoconazole
- Erythromycin
- Clarithromycin
- Amiodarone
- Quinidine
- Fluconazole
- Ritonavir
- Saquinavir
- Telaprevir
- Voriconazole
โก Moderate Interactions
- Cimetidine
- Ranitidine
- Omeprazole
- Phenothiazines
- Tricyclic antidepressants
- SSRIs
- MAOIs
- Lithium
- Opioid analgesics
- Anticholinergics
โน๏ธ Minor Interactions
- Aluminum-containing antacids
- Sucralfate
- Digoxin
- Paracetamol
- Diazepam
๐ฝ๏ธ Food Interactions
Food may reduce absorption; take 15-30 minutes before meals. Grapefruit juice may increase plasma levels.
๐ท Alcohol Interaction
Alcohol may enhance sedative effects and increase risk of extrapyramidal symptoms.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to domperidone; prolactinoma; gastrointestinal hemorrhage, obstruction, or perforation; moderate to severe hepatic impairment; known QT prolongation or concurrent use of QT-prolonging drugs.
๐ Monitoring Parameters
ECG for QT interval in patients at risk; renal function; signs of extrapyramidal symptoms; gastrointestinal symptoms.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution. May cause adverse effects in nursing infants.
๐ Overdose Management
Symptoms: drowsiness, disorientation, extrapyramidal reactions. Treatment: gastric lavage, activated charcoal, supportive care. Anticholinergic agents may be used for extrapyramidal symptoms.
โฐ Missed Dose
Take the missed dose as soon as remembered. If it is almost time for the next dose, skip the missed dose. Do not double the dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for anglodom 1mg/ml drop
View AllAlternative brands with exact same active ingredient (Domperidone (1mg/ml)):
-
eldostal 1mg/ml suspensionElder Pharmaceuticals Ltd โน9.38 25% CHEAPER
-
toyodom 1mg syrupBiochem Pharmaceutical Industries โน11.25 10% CHEAPER
-
domcon 1mg/ml syrupIcon Pharma & Surgicals Pvt Ltd โน11.72 6.2% CHEAPER
-
domkid dropPsychotropics India Ltd โน14.88 19% COSTLIER
-
Tridom 1mg/ml SuspensionZydus Cadila โน19.49 55.9% COSTLIER
-
domdon oral suspensionBactolac Formulations Pvt Ltd โน21.09 68.7% COSTLIER
-
domne 1mg/ml suspensionRaptakos Brett & Co Ltd โน21.09 68.7% COSTLIER
-
emitin 1mg/ml suspensionCachet Pharmaceuticals Pvt Ltd โน21.09 68.7% COSTLIER
-
dompewal 1mg oral dropsWallace Pharmaceuticals Pvt Ltd โน22.97 83.8% COSTLIER
-
nausidome 1mg/ml suspensionKnoll Pharmaceuticals Ltd โน22.97 83.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.