anastra 1mg tablet - Anastrozole (1mg) medicine

Anastra 1mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Wockhardt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is anastra 1mg tablet used for?

Anastra 1mg Tablet contains Anastrozole, an aromatase inhibitor used primarily to treat breast cancer in postmenopausal women. It works by reducing estrogen production in the body, thereby slowing or stopping the growth of hormone-sensitive tumors. It is also used for early and advanced breast cancer.

  • Generic Name: Anastrozole
  • Manufacturer: Wockhardt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š anastra 1mg tablet Uses & Benefits

Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women; first-line treatment of advanced breast cancer in postmenopausal women.

Off-label uses: Male breast cancer, gynecomastia, ovulation induction (in combination with other agents).

๐Ÿ“‹ Drug Information

Generic Name(s)Anastrozole
Brand NameArimidex
ManufacturerWockhardt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAromatase inhibitor
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; absorption is rapid and complete.
DistributionWidely distributed; crosses blood-brain barrier.
Protein Binding40% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via N-dealkylation, hydroxylation, and glucuronidation; CYP3A4 is the major enzyme involved.
Half-LifeApproximately 50 hours.
Excretion85% in feces, 10% in urine (mainly as metabolites).
Bioavailability83-85%.
Onset of ActionWithin 24 hours; maximal suppression of estradiol occurs within 3-4 days.
Peak Plasma Time2 hours.
Duration of ActionEstradiol suppression persists for up to 6 days after last dose.

How It Works

Selective nonsteroidal aromatase inhibitor; inhibits conversion of androgens to estrogens.

Mechanism Steps

1Anastrozole binds reversibly to the heme group of aromatase (CYP19A1).
2Inhibits conversion of androstenedione and testosterone to estrone and estradiol.
3Reduces circulating and local estrogen levels in peripheral tissues and breast tumors.

๐Ÿ’ก How to Take anastra 1mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โŒ ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of anastra 1mg tablet

โœ… Common Side Effects

  • Hot flashes
  • Arthralgia
  • Joint stiffness
  • Fatigue
  • Nausea
  • Headache
  • Insomnia

๐Ÿšจ Serious Side Effects

  • Osteoporosis
  • Fractures
  • Cardiovascular events (e.g., myocardial infarction)
  • Severe skin reactions
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Thromboembolism
  • Endometrial cancer (unlikely due to estrogen suppression)
  • Allergic reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tamoxifen Moderate Reduced anastrozole efficacy
Estrogen-containing therapies Major Counteracts anastrozole effect
Warfarin Minor Possible increased INR

๐Ÿšจ Major Interactions

  • Tamoxifen
  • Estrogen-containing therapies

โšก Moderate Interactions

  • Warfarin
  • CYP3A4 inducers (e.g., rifampin)
  • CYP3A4 inhibitors (e.g., ketoconazole)

โ„น๏ธ Minor Interactions

  • None known

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Pregnancy, lactation, hypersensitivity to anastrozole, premenopausal women (unless ovarian suppression).

๐Ÿ“Š Monitoring Parameters

Estradiol levels, bone mineral density, lipid profile, liver function tests.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in milk in animal studies.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; induce emesis if recent ingestion.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for anastra 1mg tablet

View All

Alternative brands with exact same active ingredient (Anastrozole (1mg)):

Medical Note: Always consult your doctor before switching medications.

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