anastar 1mg tablet - Anastrozole (1mg) medicine

Anastar 1mg Tablet - Uses, Price, Side Effects

4.5 (16 reviews)

Anastrozole (1mg)

🏭 Ardez Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is anastar 1mg tablet used for?

Anastar 1mg Tablet contains Anastrozole, an aromatase inhibitor used primarily to treat hormone receptor-positive breast cancer in postmenopausal women. It works by reducing estrogen production in the body, thereby slowing or stopping the growth of cancer cells that require estrogen to grow.

Generic Name: Anastrozole
Manufacturer: Ardez Pharma
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 anastar 1mg tablet Uses & Benefits

Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women; first-line treatment of advanced breast cancer in postmenopausal women.

Off-label uses: Male breast cancer, gynecomastia, ovulation induction (in combination with other agents).

📋 Drug Information

Generic Name(s)	Anastrozole
Brand Name	Arimidex
Manufacturer	Ardez Pharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI NEOPLASTICS
Action Class	Aromatase inhibitor
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; absorption is rapid and complete.

DistributionWidely distributed; crosses blood-brain barrier.

Protein Binding40% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via N-dealkylation, hydroxylation, and glucuronidation; CYP3A4 is the major enzyme involved.

Half-LifeApproximately 50 hours.

Excretion85% in feces, 10% in urine (mainly as metabolites).

Bioavailability83-85%.

Onset of ActionWithin 24 hours; maximal suppression of estradiol occurs within 3-4 days.

Peak Plasma Time2 hours.

Duration of ActionEstradiol suppression persists for up to 6 days after last dose.

How It Works

Selective nonsteroidal aromatase inhibitor; inhibits conversion of androgens to estrogens.

Mechanism Steps

1Anastrozole binds reversibly to the heme group of aromatase (CYP19A1).

2Inhibits conversion of androstenedione and testosterone to estrone and estradiol.

3Reduces circulating and local estrogen levels in peripheral tissues and breast tumors.

💡 How to Take anastar 1mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of anastar 1mg tablet

✅ Common Side Effects

Hot flashes
Arthralgia
Joint stiffness
Fatigue
Nausea
Headache
Insomnia

🚨 Serious Side Effects

Osteoporosis
Fractures
Cardiovascular events (e.g., myocardial infarction)
Severe skin reactions
Hepatotoxicity

⚠️ Rare Side Effects

Thromboembolism
Endometrial cancer (unlikely due to estrogen suppression)
Allergic reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Tamoxifen	Major	Reduced anastrozole efficacy
Estrogen-containing therapies	Major	Counteracts anastrozole effect
Warfarin	Moderate	Increased INR and bleeding risk

🚨 Major Interactions

Tamoxifen
Estrogen-containing therapies

⚡ Moderate Interactions

Warfarin
CYP3A4 inducers (e.g., rifampin)
CYP3A4 inhibitors (e.g., ketoconazole)

ℹ️ Minor Interactions

None known

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Pregnancy, lactation, hypersensitivity to anastrozole, premenopausal women (unless ovarian suppression).

📊 Monitoring Parameters

Estradiol levels, bone mineral density, lipid profile, liver function tests.

🤱 Lactation Safety

Not recommended; excreted in milk in animal studies.

💊 Overdose Management

No specific antidote; supportive care; induce emesis if recent ingestion.

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for anastar 1mg tablet

View All

Alternative brands with exact same active ingredient (Anastrozole (1mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.