anaspas 25mg injection - Camylofin (25mg) + Diclofenac (25mg) medicine

Anaspas 25mg Injection: Complete Medicine Guide

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🏭 Abbott 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not classified by outdated letter categories. Diclofenac is generally avoided in the third trimester due to risk of premature closure of ductus arteriosus and maternal/fetal bleeding. Use in early pregnancy only if clearly needed and after consulting a doctor. Camylofin safety in pregnancy is not well established. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination; individual components well-established.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is anaspas 25mg injection used for?

This medicine is a prescription injection combining Camylofin (an antispasmodic) and Diclofenac (an NSAID) used for rapid relief of severe spasmodic pain such as renal colic, biliary colic, and severe menstrual cramps. It is given by a healthcare professional and is not for self-administration.

  • Generic Name: Camylofin + Diclofenac
  • Manufacturer: Abbott
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anaspas 25mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा कैमिलोफिन और डाइक्लोफेनाक का संयोजन है, जिसका उपयोग तीव्र ऐंठन वाले दर्द जैसे गुर्दे की पथरी का दर्द, पित्ताशय की ऐंठन, और गंभीर मासिक धर्म के दर्द में राहत के लिए किया जाता है। यह इंजेक्शन के रूप में डॉक्टर या नर्स द्वारा दिया जाता है और इसे घर पर स्वयं नहीं लगाया जाना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में असहजता, चक्कर आना, और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी, गुर्दे की समस्या, और हृदय संबंधी घटनाएं शामिल हो सकती हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह इंजेक्शन केवल योग्य डॉक्टर या नर्स द्वारा ही दिया जाना चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं, अन्य दर्द निवारक दवाएं, और ब्लड प्रेशर या गुर्दे की दवाएं। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। काली मल, गंभीर पेट दर्द, पेशाब कम आना, या चेहरे/गले में सूजन होने पर तुरंत डॉक्टर को बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 anaspas 25mg injection Uses & Benefits

[{"condition":"Renal colic","description":"Provides rapid relief of severe flank pain caused by kidney stones by relaxing ureteral smooth muscle and reducing inflammation.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Relieves intense upper abdominal pain from gallbladder spasms by reducing smooth muscle spasm and inflammation.","evidence":"Well-established"},{"condition":"Severe dysmenorrhea","description":"Alleviates severe menstrual cramps by reducing uterine spasms and prostaglandin-mediated pain.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Used for short-term management of severe musculoskeletal pain when oral therapy is not suitable.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Postoperative pain","description":"Sometimes used off-label for short-term management of postoperative spasmodic pain.","evidence":"Limited"},{"condition":"Acute gout","description":"May be used off-label for acute gout attacks when other treatments are contraindicated.","evidence":"Limited"}]

Primary treatment for: Acute spasmodic pain (renal colic, biliary colic, severe dysmenorrhea)

Also treats: Musculoskeletal pain, Postoperative pain

📋 Drug Information

Generic Name(s)Camylofin + Diclofenac
Brand NameAnaspas Tablet
ManufacturerAbbott
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + NSAID
Route of AdministrationParenteral (intramuscular or intravenous injection). Must be administered by a qualified healthcare professional
StorageStore in a cool, dry place, protected from light. Do not freeze. Keep out of reach of children. Store in the original packaging.
Shelf LifeTypically 24 months from the date of manufacture. Check the expiry date on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this injection only in a healthcare setting with resuscitation facilities available.
2
Assess renal and hepatic function before administration, especially in elderly or dehydrated patients.
3
Use the lowest effective dose for the shortest duration to minimize side effects.
4
Monitor for signs of gastrointestinal bleeding, especially in patients on anticoagulants or with a history of ulcers.
5
Avoid concurrent use with other NSAIDs to prevent additive toxicity.
6
Consider alternative analgesics in patients with cardiovascular risk factors.
7
Instruct patients to report any unusual bleeding, bruising, or decreased urine output immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Severe flank pain
This medicine is commonly prescribed for renal colic.
Likely Use
Severe menstrual cramps
This medicine can relieve severe dysmenorrhea.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Mild headache
This medicine is not intended for mild headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular administration, diclofenac is rapidly and completely absorbed, with peak plasma concentrations reached within 10 to 30 minutes. Camylofin is also absorbed systemically after injection, although specific pharmacokinetic data for the combination are not well established.
DistributionDiclofenac is highly bound to plasma proteins and distributes widely into tissues, including synovial fluid. Camylofin distribution is not well characterized but is expected to distribute to smooth muscle tissues.
Protein BindingDiclofenac is approximately 99% bound to plasma proteins, primarily albumin. Protein binding of camylofin is not established from the available information.
MetabolismDiclofenac is extensively metabolized in the liver, primarily by cytochrome P450 enzymes CYP2C9 and CYP3A4, through hydroxylation and conjugation. Camylofin metabolism is not well established from the available information.
Half-LifeThe elimination half-life of diclofenac is approximately 1 to 2 hours. The half-life of camylofin is not established from the available information.
ExcretionDiclofenac metabolites are excreted mainly in urine (about 65%) and bile/feces (about 35%). Camylofin excretion is not established from the available information.
BioavailabilityIntramuscular diclofenac has high bioavailability, approximately 90% or more. Bioavailability of camylofin from injection is not established from the available information.
Onset of ActionPain relief typically begins within 10 to 20 minutes after intramuscular injection.
Peak Plasma TimePeak plasma concentration of diclofenac occurs approximately 10 to 30 minutes after intramuscular injection. Peak for camylofin is not established.
Duration of ActionPain relief usually lasts 4 to 6 hours, depending on the individual and the severity of pain.

How It Works

Camylofin is an antispasmodic that acts directly on smooth muscle cells, likely by inhibiting calcium influx and interfering with the contractile process, leading to relaxation of spasms in the gastrointestinal, biliary, and genitourinary tracts. Diclofenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. The combination provides both antispasmodic and anti-inflammatory effects, offering rapid relief from spasmodic pain.

Mechanism Steps

1
Camylofin relaxes smooth muscle: Camylofin acts on smooth muscle cells to reduce calcium-mediated contraction, leading to relaxation of spasms in the affected organs.
2
Diclofenac inhibits COX enzymes: Diclofenac binds to and reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandins.
3
Reduced prostaglandin synthesis: Lower prostaglandin levels decrease pain signaling, inflammation, and uterine or smooth muscle contractions.
4
Combined antispasmodic and anti-inflammatory effect: The two ingredients work together to relieve both the spasm and the inflammatory component of pain, providing rapid symptomatic relief.

💡 How to Take anaspas 25mg injection

Strength: Injection containing Camylofin 25 mg and Diclofenac 25 mg per dose.

1This medicine is given by a healthcare professional as an intramuscular or intravenous injection.
2Do not attempt to self-administer.
3The injection site will be cleaned before administration.
4Report any pain, redness, or swelling at the injection site.
5After injection, remain under observation for a short period as advised by your doctor.

Dosage Information

Adult DosageThe usual adult dose is one injection (containing Camylofin 25 mg and Diclofenac 25 mg) given intramuscularly or intravenously, as needed for pain relief, typically every 8 to 12 hours. The maximum daily dose should not exceed 2 injections in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and severity of pain. This medicine is for short-term use only.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Avoid in severe kidney impairment (eGFR <30 mL/min). Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 2 injections (total Camylofin 50 mg and Diclofenac 50 mg) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals if oral form is used
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your healthcare provider for guidance.
💡 Do not self-administer an extra dose.
📌 More than half the dosing interval has passed
→ Skip the missed dose and continue with the regular schedule.
💡 Do not double dose to catch up.

⚠️ Side Effects of anaspas 25mg injection

✅ Common Side Effects

Nausea (Common (5-10%))
Usually resolves on its own. If persistent, inform your doctor.
Vomiting (Common (5-10%))
Stay hydrated with small sips of water. Consult doctor if severe.
Abdominal discomfort (Common (5-10%))
Usually transient. Report if it becomes severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.
Injection site pain (Common (5-10%))
Apply a cold compress if needed. Report if redness or swelling worsens.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stools, vomiting blood, or severe abdominal pain.
Anaphylaxis (Rare (<0.1%))
Call emergency services immediately if you experience swelling of face, lips, throat, difficulty breathing, or a severe rash.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor promptly.
Cardiovascular events (Rare (<0.1%))
Seek medical help if you experience chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain immediately.
Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
ACE inhibitors Major
Diuretics Major
Lithium Major
Corticosteroids Moderate
Methotrexate Moderate
SSRIs Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • ACE inhibitors / ARBs
  • Diuretics
  • Lithium

⚡ Moderate Interactions

  • Corticosteroids
  • Methotrexate
  • SSRIs

🍷 Alcohol Interaction

Alcohol should be strictly avoided while receiving this medicine. Concurrent use increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity. It may also enhance central nervous system side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment (eGFR

⚠️ Warnings & Precautions

["Use with caution in elderly patients due to increased risk of GI bleeding and kidney injury.","Avoid in patients with dehydration or hypovolemia.","Monitor for signs of bleeding, especially in patients on anticoagulants.","Do not use for prolonged periods without medical supervision.","May mask signs of infection.","Use with caution in patients with cardiovascular risk factors.","Not recommended for self-administration; must be given by a healthcare professional."]

🤱 Lactation Safety

Diclofenac is excreted in breast milk in small amounts. Camylofin excretion in breast milk is not established. Consult a doctor before use during breastfeeding; alternative treatments may be preferred.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and kidney failure. There is no specific antidote. Treatment is supportive and symptomatic, including activated charcoal if recent ingestion, gastric lavage, and monitoring of vital signs and renal function. Hemodialysis is not effective for diclofenac removal. Seek immediate medical attention.

⏰ Missed Dose

This medicine is typically given as a single dose or as directed by your doctor. If you miss a scheduled dose, contact your healthcare provider for guidance. Do not self-administer an extra dose.

Additional Safety Advice

General Safety

This injection must be given by a qualified healthcare professional only. Do not attempt to self-administer. Inform your doctor about all medications you are taking, especially blood thinners, other NSAIDs, or drugs for blood pressure or kidney problems. Avoid alcohol during treatment as it can increase the risk of stomach bleeding. Report any unusual symptoms such as black stools, severe abdominal pain, decreased urine output, or swelling of the face or throat immediately. Use the lowest effective dose for the shortest duration necessary.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid concurrent use with other NSAIDs or anticoagulants unless absolutely necessary.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Diclofenac may affect ovulation and is generally avoided in the third trimester. Camylofin safety in pregnancy is not well established. Discuss alternative pain management options with your healthcare provider.

🏥 Post-Surgery Considerations

This medicine may be used for short-term postoperative pain management, but it should not be used in the perioperative period of coronary artery bypass graft (CABG) surgery due to increased cardiovascular risk. Consult your surgeon and anesthesiologist before use.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, as it may increase bleeding risk during dental procedures. Your dentist may recommend postponing elective procedures or taking precautions. Do not stop the medicine without consulting your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and organs.
🥗
Stay well hydrated to support kidney function.
😴
Avoid alcohol to reduce the risk of gastrointestinal bleeding.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids in your diet.
🧘
Get adequate rest and sleep to aid recovery.
🌞
Follow up regularly with your doctor for monitoring.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting immediately after receiving this injection, as it may cause dizziness or drowsiness. Gradually resume activities as tolerated. Consult your doctor before starting any exercise program if you have underlying heart, kidney, or liver conditions.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce processed and high-fat foods.
Stay well hydrated with water and clear fluids.
Avoid alcohol and grapefruit juice.
Eat small, frequent meals to reduce stomach upset.

💼 Impact on Daily Work & Life

This injection may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. It is usually given in a clinical setting, and you may need someone to drive you home. Discuss with your doctor about returning to work, especially if your job involves physical labor or operating machinery.

🛑 When to Stop This Medicine

This medicine is for short-term use only. Stop and consult your doctor if you experience severe side effects such as black stools, severe abdominal pain, decreased urine output, or allergic reactions. Do not stop prescribed treatment without consulting your doctor, especially if you have underlying conditions.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. If prolonged therapy is necessary, regular monitoring of kidney and liver function, blood counts, and blood pressure is required. Consult your doctor for alternative treatments if long-term pain management is needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral analgesics

Oral NSAIDs or antispasmodics may be used for milder pain.

Evidence: Well-established
Physical therapy

Can complement medicine for chronic pain management.

Evidence: Well-established
Heat therapy

Local heat application can help relax muscles and reduce pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about this medicine. It is generally safe to receive vaccines while on this medicine, but individual circumstances may vary.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

This medicine is given by a healthcare professional and is not typically self-administered during travel. If you are prescribed this injection while traveling, carry it in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight. Check customs regulations for carrying injectable medicines across borders. It is advisable to have a medical letter explaining the need for the injection.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute renal colic
He presented to the emergency department with severe flank pain. He received this injection intramuscularly and reported significant pain relief within 15 minutes. He was monitored for 2 hours and discharged with oral pain medication.
💡 Lesson: This injection provides rapid relief for severe spasmodic pain in a supervised setting.
👤 A 28-year-old woman with severe dysmenorrhea
She had incapacitating menstrual cramps that did not respond to oral painkillers. She was given this injection at a clinic and experienced relief within 20 minutes. She was advised to follow up with her gynecologist for long-term management.
💡 Lesson: This medicine can be effective for severe menstrual cramps when oral therapy fails, but it is not for routine self-use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 10 to 20 minutes after injection.

Q: How long does the effect last?

A: The effect usually lasts 4 to 6 hours.

Q: Can I take this medicine at home?

A: No, this injection must be given by a healthcare professional in a clinical setting.

Q: Is it safe during pregnancy?

A: It is generally avoided in the third trimester. Consult your doctor if you are pregnant or planning pregnancy.

Q: What are the common side effects?

A: Common side effects include nausea, vomiting, dizziness, and injection site pain.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anaspas 25mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This injection can be self-administered at home.
    Fact: This medicine must be given by a qualified healthcare professional only. Self-administration is dangerous.
  • Myth: It is safe to use for any type of pain.
    Fact: It is specifically for spasmodic pain and should not be used for all pain types without medical advice.
  • Myth: It can be used long-term for chronic pain.
    Fact: It is intended for short-term use only. Long-term use increases the risk of serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Camylofin + Diclofenac injection (generic)

Brand Alternatives

  • Anaspas 25mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Camylofin + Diclofenac","composition":"Camylofin 25 mg + Diclofenac 25 mg","route":"Parenteral","onset":"10-20 minutes","duration":"4-6 hours"},{"medicine":"Dicyclomine + Diclofenac","composition":"Dicyclomine 20 mg + Diclofenac 50 mg","route":"Parenteral","onset":"10-20 minutes","duration":"4-6 hours"},{"medicine":"Drotaverine + Diclofenac","composition":"Drotaverine 40 mg + Diclofenac 50 mg","route":"Parenteral","onset":"10-20 minutes","duration":"4-6 hours"}]

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