Anafebrin 100mg Tablet - Uses, Price, Side Effects
What is anafebrin 100mg tablet used for?
Anafebrin 100mg Tablet contains Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve acute pain and fever. It works by blocking the production of prostaglandins, chemicals that cause inflammation and pain. It is typically taken twice daily after meals. Not recommended for long-term use or in children under 12 years.
- Generic Name: Nimesulide
- Manufacturer: Themis Medicare Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ anafebrin 100mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Nimesulide |
| Brand Name | Aulin 100mg Tablet |
| Manufacturer | Themis Medicare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's-Non-Selective COX 1&2 Inhibitors (Others) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take anafebrin 100mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of anafebrin 100mg tablet
โ Common Side Effects
- Nausea
- Dyspepsia
- Diarrhea
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Gastrointestinal bleeding
- Stevens-Johnson syndrome
- Acute renal failure
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Moderate | Increased risk of gastrointestinal ulceration |
| Lithium | Moderate | Increased lithium levels and toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Diuretics | Moderate | Reduced diuretic effect |
๐จ Major Interactions
- Warfarin
- Aspirin
- Methotrexate
- Lithium
- Anticoagulants
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Corticosteroids
- Antiplatelet agents
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Food may delay absorption but does not significantly affect bioavailability.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to nimesulide or NSAIDs, active peptic ulcer, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), lactation, children <12 years.
๐ Monitoring Parameters
Liver function tests, renal function, blood pressure, signs of GI bleeding.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for anafebrin 100mg tablet
View AllAlternative brands with exact same active ingredient (Nimesulide (100mg)):
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nulide 100mg tabletNeon Laboratories Ltd โน2.15 87.4% CHEAPER
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nimley 100mg tabletMedley Pharmaceuticals โน2.23 86.9% CHEAPER
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nimucon 100mg tabletConcept Pharmaceuticals Ltd โน2.31 86.4% CHEAPER
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genlide 100mg tabletCadila Pharmaceuticals Ltd โน2.34 86.2% CHEAPER
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nimopen 100mg tabletMorepen Laboratories Ltd โน2.34 86.2% CHEAPER
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nes tabletPCI Pharmaceuticals โน2.93 82.8% CHEAPER
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arpinim 100mg tabletRPG Life Sciences Ltd โน3.20 81.2% CHEAPER
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enlide 100mg tabletTablets India Limited โน3.52 79.3% CHEAPER
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nimus 100mg tabletInd Swift Laboratories Ltd โน3.52 79.3% CHEAPER
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jumolid 100mg tabletPsychotropics India Ltd โน4.00 76.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.