amuscar 80mg tablet - Drotaverine (80mg) medicine

amuscar 80mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Befam Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is amuscar 80mg tablet used for?

Antispasmin DS 80mg Tablet (Drotaverine) is used to treat GASTRO INTESTINAL. It contains Drotaverine (80mg), which Inhibits phosphodiesterase-4 (PDE4), increasing cAMP, leading to smooth muscle r. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Drotaverine
  • Manufacturer: Befam Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š amuscar 80mg tablet Uses & Benefits

Smooth muscle spasms in GI disorders, biliary colic, renal colic, dysmenorrhea.

Off-label uses: Premature labor (not FDA approved).

๐Ÿ“‹ Drug Information

Generic Name(s)Drotaverine
Brand NameAntispasmin DS 80mg Tablet
ManufacturerBefam Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassPhosphodiesterase-IV inhibitors (Smooth Muscle Relaxant)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration.
DistributionWidely distributed in body tissues.
Protein Binding95-98%
MetabolismHepatic, primarily via CYP2D6 and CYP3A4.
Half-Life7-12 hours
ExcretionRenal (50% as metabolites, 10% unchanged) and fecal.
Bioavailability~50%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours

How It Works

Inhibits phosphodiesterase-4 (PDE4), increasing cAMP, leading to smooth muscle relaxation.

Mechanism Steps

1Inhibition of PDE4 enzyme
2Increased intracellular cAMP levels
3Activation of protein kinase A

๐Ÿ’ก How to Take amuscar 80mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amuscar 80mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • Hypotension
  • Arrhythmias
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Leukopenia
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Levodopa Major Reduced efficacy of levodopa
Tricyclic antidepressants Major Increased anticholinergic effects
Antihypertensives Moderate Additive hypotensive effect
Other anticholinergics Moderate Increased anticholinergic side effects
Cimetidine Minor Possible increased drotaverine levels
Ranitidine Minor Possible increased drotaverine levels

๐Ÿšจ Major Interactions

  • Levodopa
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Antihypertensives
  • Other anticholinergics

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ranitidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May increase risk of hypotension and dizziness.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to drotaverine, severe hepatic or renal impairment, porphyria.

๐Ÿ“Š Monitoring Parameters

Blood pressure, liver function tests in long-term use.

๐Ÿคฑ Lactation Safety

Caution advised; excreted in breast milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for amuscar 80mg tablet

View All

Alternative brands with exact same active ingredient (Drotaverine (80mg)):

Medical Note: Always consult your doctor before switching medications.

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